Therapeutic Uses of Prostaglandins in Mares
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Questions and Answers

What is the primary purpose of prostaglandins in the context of mare reproductive health?

  • To induce parturition (correct)
  • To prevent late abortions
  • To increase milk production
  • To enhance fertility rates
  • Which method is primarily used for cervical ripening in mares before parturition?

  • Prostaglandin E2 gel (correct)
  • Progesterone supplementation
  • Estrogen therapy
  • Oxytocin injection
  • What is the role of oxytocin in mare reproductive processes?

  • To inhibit uterine contractions
  • To regulate genital tract pressures (correct)
  • To induce ovulation
  • To extend the gestation period
  • Elective termination of pregnancy in mares is primarily associated with which of the following?

    <p>Cervical ripening with prostaglandin E2</p> Signup and view all the answers

    Which agent is compared for its effectiveness in inducing parturition in mares?

    <p>Prostaglandin F2α</p> Signup and view all the answers

    The effect of PGE2 on mares primarily relates to what physiological response?

    <p>Enhances oviductal transport of embryos</p> Signup and view all the answers

    What is a documented effect of prostaglandin F2α in mares?

    <p>Termination of pregnancy</p> Signup and view all the answers

    Which aspect of mare reproductive health is primarily influenced by hormonal changes during abortion?

    <p>Preparation of the cervix for delivery</p> Signup and view all the answers

    What is the primary hormone discussed that affects cervical ripening during labor in mares?

    <p>Prostaglandin E2</p> Signup and view all the answers

    What is the effect of administering oxytocin during the periovulatory period in mares?

    <p>Increases luteal formation</p> Signup and view all the answers

    Which procedure is associated with the administration of prostaglandins in labor induction?

    <p>Cervical priming</p> Signup and view all the answers

    What is the primary indication for the use of prostaglandin F2α in mares?

    <p>Enhancing fertility rates</p> Signup and view all the answers

    What primary factor is influenced by cervical musculature sensitivity to prostaglandin E2?

    <p>The induction of labor</p> Signup and view all the answers

    Why might cloprostenol be administered in a reproductive context in mares?

    <p>To enhance cervical dilation</p> Signup and view all the answers

    Which outcome is associated with the use of prostaglandin E2 gel in pregnant heifers?

    <p>Promotion of early labor</p> Signup and view all the answers

    What common reproductive issue can arise from cervical failure to dilate?

    <p>Delayed labor</p> Signup and view all the answers

    What role does progesterone play in relation to uterine infections during pregnancy?

    <p>Constricts the cervix</p> Signup and view all the answers

    What effect does PGF2α have on mares in estrus?

    <p>Increases uterine contractions</p> Signup and view all the answers

    How long do contractions induced by oxytocin typically last?

    <p>30 to 50 minutes</p> Signup and view all the answers

    What is one potential benefit of administering PGE2 to ram semen?

    <p>Increased pregnancy rates after artificial insemination</p> Signup and view all the answers

    How does estradiol affect the uterus in comparison to progesterone?

    <p>Stimulates uterine contractions</p> Signup and view all the answers

    What is the effect of PGE2 administration on the oviduct in equines?

    <p>Induces relaxation of smooth muscle</p> Signup and view all the answers

    What is the primary action of PGF2α in relation to the cervix?

    <p>It allows estrus to occur</p> Signup and view all the answers

    What physiological role does PGE2 play in enhancing spermatozoal transport?

    <p>Stimulates oviductal smooth muscle contraction</p> Signup and view all the answers

    How does the effect of prostaglandins on uterine contractions differ from that of oxytocin?

    <p>Prostaglandins produce low-amplitude contractions that persist longer</p> Signup and view all the answers

    What is the effect of PGE2 when combined with estrogens for parturition protocols?

    <p>Dilates the cervix</p> Signup and view all the answers

    Study Notes

    Therapeutic Uses of Prostaglandins

    • Prostaglandin F2α (PGF2α) plays a critical role in uterine health and function by stimulating myometrial activity.
    • PGF2α is used clinically to induce estrus in mares by shortening the diestrus phase, thus increasing estrogen levels and cervical dilation.
    • In mares with endometritis, PGF2α helps clear uterine infections by increasing uterine contractions and assisting in the removal of inflammatory material.
    • PGF2α is used to induce labor in mares when necessary. It is effective for both pre-viable and premature periods of gestation.

    Prostaglandin E2 (PGE2) Roles

    • PGE2 plays a significant role in gamete and embryo transport through the oviduct by stimulating oviductal smooth muscle contractions.
    • Local application of PGE2 relaxes circular smooth muscle of the oviductal isthmus, facilitating embryo transport.
    • PGE2 can accelerate spermatozoal transport through the reproductive tract, potentially contributing to increased pregnancy rates after artificial insemination.
    • PGE2 can be used to ripen the cervix prior to inducing parturition. It can also be combined with estrogens to further facilitate cervical dilation.

    Prostaglandins for Reproductive Management

    • PGF2α is used to induce ovulation in mares and to synchronize estrus in a group of mares.
    • PGF2α can be used to treat luteal cysts and induce luteolysis in mares.
    • PGE2 has been shown to improve oviductal patency and fertility in infertile mares.
    • Both PGF2α and PGE2 are being investigated for their potential to improve pregnancy rates in mares.

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    Description

    This quiz explores the therapeutic uses of prostaglandins, particularly PGF2α and PGE2, in equine reproductive health. Learn how these compounds influence uterine function, aid in labor induction, and promote embryo transport. Whether you are studying veterinary medicine or equine biology, this quiz offers valuable insights into prostaglandin applications.

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