Tablet Manufacturing Processes Quiz

Tablet Manufacturing Processes

• Maximum limit of poorly compressible ingredient allowed in direct compression is 20-30%.

Choice of Granulation Process

• The main reason for choosing wet granulation over direct compression is to improve flow and compressibility of materials.

Purposes of Granulation

• The main purposes of granulation are to improve flow and compressibility of materials, and to reduce dust and segregation problems.

Suitable Processes for Moisture-Sensitive Materials

• Dry granulation is suitable for moisture-sensitive materials without the need for a drying step.

Tablet Shape and Dimension

• The shape and dimension of a tablet are determined by the die shape and punch configuration.

Slugging Process

• Slugging is a process where granules are formed by compacting powders without added moisture.

Suitable Processes for Poorly Compressible Materials

• Wet granulation is suitable for poorly compressible materials and those with poor flow properties.

Advantages of Wet Granulation

• The main advantage of wet granulation over dry granulation is that it provides better binding properties.

Dry Granulation Process

• Dry granulation creates granules by forming slugs and then milling them into smaller particles.

Disadvantages of Dry Granulation

• The main disadvantage of dry granulation is that it may not provide sufficient binding properties.

Tabletting Compaction Process

• The tabletting compaction process involves the reduction of bulk volume of powder in a die cavity under pressure.

Limitations of Wet Granulation

• The main limitation of wet granulation is that it requires a drying step, which can be time-consuming and affect the stability of some materials.

Ideal Process for Moisture-Sensitive Materials

• Dry granulation is ideal for moisture-sensitive and heat-sensitive materials without the need for a drying step.