Tablet Manufacturing Processes Quiz

What is the maximum limit of poorly compressible ingredient allowed in direct compression for tablet manufacturing?

What is the main reason for choosing wet granulation over direct compression for tablet manufacturing?

What are the main purposes of granulation?

Which process is suitable for moisture-sensitive materials without the need for a drying step?

What determines the shape and dimension of a tablet?

In which process are granules formed by compacting powders without added moisture?

Which process is suitable for poorly compressible materials and those with poor flow properties?

What is the main advantage of wet granulation over dry granulation?

Which process creates granules by forming slugs and then milling them into smaller particles?

What is the main disadvantage of dry granulation?

Which tabletting compaction process involves the reduction of bulk volume of powder in a die cavity under pressure?

What is the main limitation of wet granulation?

Which process is ideal for moisture-sensitive and heat-sensitive materials without the need for a drying step?

Tablet Manufacturing Processes

Maximum limit of poorly compressible ingredient allowed in direct compression is 20-30%.

Choice of Granulation Process

The main reason for choosing wet granulation over direct compression is to improve flow and compressibility of materials.

Purposes of Granulation

The main purposes of granulation are to improve flow and compressibility of materials, and to reduce dust and segregation problems.

Suitable Processes for Moisture-Sensitive Materials

Dry granulation is suitable for moisture-sensitive materials without the need for a drying step.

Tablet Shape and Dimension

The shape and dimension of a tablet are determined by the die shape and punch configuration.

Slugging Process

Slugging is a process where granules are formed by compacting powders without added moisture.

Suitable Processes for Poorly Compressible Materials

Wet granulation is suitable for poorly compressible materials and those with poor flow properties.

Advantages of Wet Granulation

The main advantage of wet granulation over dry granulation is that it provides better binding properties.

Dry Granulation Process

Dry granulation creates granules by forming slugs and then milling them into smaller particles.

Disadvantages of Dry Granulation

The main disadvantage of dry granulation is that it may not provide sufficient binding properties.

Tabletting Compaction Process

The tabletting compaction process involves the reduction of bulk volume of powder in a die cavity under pressure.

Limitations of Wet Granulation

The main limitation of wet granulation is that it requires a drying step, which can be time-consuming and affect the stability of some materials.

Ideal Process for Moisture-Sensitive Materials

Dry granulation is ideal for moisture-sensitive and heat-sensitive materials without the need for a drying step.

Test your knowledge of tablet manufacturing processes with this quiz. Explore the differences between direct compression and granulation (wet and dry) methods, and understand the key factors affecting the production of tablets, such as ingredient compressibility and flowability.