6 Questions
Which type of T cells are responsible for directly killing host cells?
CD8+ T cells
Which type of T cells produce cytokines, including IFN-γ, that may induce inflammation in some hypersensitivity diseases?
CD8+ T cells
In which type of autoimmune diseases are both CD4+ T cells and CD8+ T cells specific for self antigens present?
T cell–mediated autoimmune diseases
Which cells are responsible for the recruitment of leukocytes, including neutrophils, in T cell-mediated diseases?
Th17 cells
What is the principal macrophage-activating cytokine produced by Th1 cells?
Interferon-γ (IFN-γ)
What is the typical reaction mediated by T cell cytokines called?
Delayed-type hypersensitivity (DTH)
Test your knowledge on T cell-mediated diseases and the mechanisms of tissue injury caused by CD4+ T cells and CD8+ cytotoxic T lymphocytes. Explore how these mechanisms are similar to those used by T cells to eliminate cell-associated microbes.
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