10 Questions
What are the two main types of T-cell mediated immune responses?
CMI Transferred through cells not antibody
What are the functionally distinct subsets of CD4+ T-cells that produce different cytokines and eliminate different types of pathogens?
Helper T Cells
Which type of T-cell recognizes both intra and extracellular microbes?
CD4+ T-cell
What are the stages of antigen recognition by T-cells?
NC in lymphoid organs, EC in tissues
What are the two types of responses produced by functionally distinct subsets of CD4+ T-cells?
Mycobacteria (escape) and Helminths (eosinophils and IgGs)
What are the regions that are required for structural integrity and for effector functions in antigen receptor molecules?
Constant regions (C)
What do B-lymphocytes recognize in addition to shapes and conformations of native macromolecules?
Simple chemical groups
Where is the sequence variability concentrated within antigen receptor molecules?
Hyper variable regions or COMPLEMENTARY DETERMINING REGIONS (CDRs)
What do T-lymphocytes recognize when displayed on APCs bound to major histocompatibility complex molecules?
Peptides
What are the general features that are important for functions of antigen receptors in adaptive immunity?
Recognition of native macromolecules and simple chemical groups
Test your knowledge of T cell-mediated immune responses with this quiz. Explore the types of T-cell mediated responses, the development and function of CD4+ effector T-lymphocytes, and the differentiation and function of CD8+ cytotoxic T-lymphocytes. Dive into the resistance of pathogenic microbes to cell-mediated immunity and enhance your understanding of this critical aspect of the immune system.
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