The Cell-Mediated Immune Response Quiz

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What is the role of a T helper cell in cell-mediated specific immune response?

Activating other immune cells and coordinating the immune response

What is the main function of a T killer cell in the cell-mediated specific immune response?

Destroying infected cells by inducing apoptosis

What are the steps involved for a T killer cell to lyse an infected cell?

Recognition, activation, and killing

Match the following components with their roles in cell-mediated specific immune response:

T helper cell = Coordinates the immune response and activates T killer cells T killer cell = Destroys infected cells through lysis Infected cell = Target of T killer cell for destruction Antigen presenting cell = Presents antigens to T cells for activation

Match the following steps with the process of T killer cell lysis of infected cells:

Recognition of infected cell = T killer cell identifies the infected cell Formation of immunological synapse = T killer cell forms a connection with the infected cell Release of cytotoxic granules = T killer cell releases granules containing perforin and granzymes Induction of apoptosis = Infected cell undergoes programmed cell death

Match the following immune responses with their primary cellular involvement:

Cell-mediated specific immune response = Involves T helper and T killer cells Humoral immune response = Involves B cells and antibodies Innate immune response = Involves natural killer cells and macrophages Adaptive immune response = Involves T and B cells with memory

Study Notes

T Helper Cells in Cell-Mediated Immune Response

  • T helper cells play a crucial role in activating and coordinating the immune response by recognizing antigens presented by antigen-presenting cells (APCs) and stimulating the activation of other immune cells, such as T killer cells and B cells.
  • They release cytokines, which are signaling molecules that help to activate and coordinate the immune response.

T Killer Cells in Cell-Mediated Immune Response

  • T killer cells, also known as cytotoxic T cells, are responsible for direct killing of infected cells or tumor cells that display viral or tumor antigens on their surface.
  • The main function of T killer cells is to recognize and eliminate infected cells or tumor cells, thereby preventing the spread of infection and tumor growth.

Steps Involved in T Killer Cell Lysis of Infected Cells

  • Recognition of infected cells: T killer cells recognize infected cells through the interaction of their T-cell receptor with the antigen presented by the major histocompatibility complex (MHC) molecules on the surface of the infected cell.
  • Release of granules: Upon recognition, T killer cells release granules containing cytotoxins, such as perforin and granzymes, which form pores in the target cell membrane.
  • Formation of immunological synapse: The T killer cell forms a tight junction with the infected cell, known as an immunological synapse, which facilitates the delivery of cytotoxins to the target cell.
  • Lysis of infected cells: The cytotoxins released by the T killer cell cause the lysis of the infected cell, thereby eliminating the source of infection.

Matching Components with Roles in Cell-Mediated Immune Response

  • T helper cells: activate and coordinate the immune response
  • T killer cells: direct killing of infected cells or tumor cells
  • Antigen-presenting cells (APCs): present antigens to T helper cells
  • Cytokines: signaling molecules that help to activate and coordinate the immune response
  • Major histocompatibility complex (MHC) molecules: present antigens on the surface of infected cells

Matching Steps with T Killer Cell Lysis of Infected Cells

  • Recognition of infected cells: interaction of T-cell receptor with antigen presented by MHC molecules
  • Release of granules: release of cytotoxins, such as perforin and granzymes
  • Formation of immunological synapse: tight junction between T killer cell and infected cell
  • Lysis of infected cells: delivery of cytotoxins to the target cell

Matching Immune Responses with Primary Cellular Involvement

  • Cell-mediated immune response: T cells (T helper cells and T killer cells)
  • Humoral immune response: B cells

Test your knowledge of the cell-mediated specific immune response with a quiz on the role of T helper cells and T killer cells. Explore the steps involved in T killer cells lysing infected cells and solidify your understanding of this crucial aspect of the immune system.

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