Systemic Lupus Erythematosus (SLE) Pathophysiology
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the underlying mechanism of Systemic Lupus Erythematosus (SLE)?

  • Infectious disease caused by virus
  • Autoimmune reaction with T-cell activation
  • Type III hypersensitivity reaction (correct)
  • Type I hypersensitivity reaction

What is the hallmark of discoid lupus in Systemic Lupus Erythematosus (SLE)?

  • Red infiltrated plaques on the hands and feet
  • Painful joints in the morning
  • Swollen lymph nodes in the armpits
  • Red infiltrated plaques on the face, neck, and scalp (correct)

What is the diagnostic criterion for Systemic Lupus Erythematosus (SLE)?

  • 3+ of clinical or antibody manifestations
  • 4+ of clinical or antibody manifestations (correct)
  • 5+ of clinical or antibody manifestations
  • 6+ of clinical or antibody manifestations

What is the primary treatment for Systemic Lupus Erythematosus (SLE)?

<p>Hydroxychloroquine and glucocorticoids (B)</p> Signup and view all the answers

What is a characteristic feature of Drug-induced Lupus?

<p>Positive ANA and anti-histone (B)</p> Signup and view all the answers

What is a common manifestation of Neonatal Lupus?

<p>Facial rash and anemia (C)</p> Signup and view all the answers

What is the primary role of Th1 cells in the context of autoimmune diseases?

<p>To stimulate macrophages with cytokine releases (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic feature of rheumatoid arthritis?

<p>Asymmetric polyarthritis (A)</p> Signup and view all the answers

What is the primary mechanism of action of TNF-a inhibitors in the treatment of rheumatoid arthritis?

<p>Blockade of TNF-a cytokine release (D)</p> Signup and view all the answers

Which of the following is a risk factor for the development of rheumatoid arthritis?

<p>Smoking (B)</p> Signup and view all the answers

What is the primary pathophysiologic mechanism underlying gout?

<p>Monosodium urate crystal deposition (A)</p> Signup and view all the answers

Which of the following medications is commonly used to treat gout?

<p>Colchicine (A)</p> Signup and view all the answers

Which autoimmune disease is characterized by the presence of anti-U1RNP antibody?

<p>Mixed Connective Tissue Disease (MCTD) (D)</p> Signup and view all the answers

What is the primary mechanism of action of TNF-a inhibitors in the treatment of Axial Spondylarthritis (SpA)?

<p>Inhibition of TNF-a release (C)</p> Signup and view all the answers

Which of the following is a characteristic radiological finding in Axial Spondylarthritis (SpA)?

<p>Syndesmophytes in the lumbar spine (A)</p> Signup and view all the answers

What is the strongest risk factor for developing Reactive Arthritis following a chlamydia infection?

<p>Male gender (A)</p> Signup and view all the answers

Which of the following is a common feature of Arthritis associated with Inflammatory Bowel Disease (IBD)?

<p>Enthesitis and dactylitis (D)</p> Signup and view all the answers

What is the primary goal of treating underlying Inflammatory Bowel Disease (IBD) in Arthritis associated with IBD?

<p>Managing gastrointestinal symptoms (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser