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LECTURE FOUR SYNTHESIS OF NON ESSENTIAL AMINO ACIDS

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12 Questions

What is the source of non-essential amino acids?

From intermediates of metabolism and essential amino acids

Which amino acid is synthesized from phenylalanine?

Tyrosine

What is the byproduct of glutamine synthesis reaction?

Ammonia

What is the donor in asparagine synthesis?

Glutamine

How is proline synthesized?

Via different alternative pathways

What is the source of cysteine?

Homocysteine and Serine

What is the condition for cysteine synthesis to continue?

Adequate dietary intake of Methionine

What is the coenzyme required for the reaction of Tyrosine formation from Phenylalanine?

BH4

What is the result of inborn errors of metabolism in amino acid metabolism?

All of the above

What is the most common inborn metabolic disease of amino acid metabolism?

Phenylketonuria (PKU)

What is characterized by high levels of Phenylalanine in tissues, plasma, and urine, and a deficiency of tyrosine?

Phenylketonuria (PKU)

What is the purpose of Newborn Screening for Phenylketonuria (PKU)?

To detect Phenylalanine hydroxylase deficiency

Learn about the synthesis of non-essential amino acids from intermediates of metabolism and essential amino acids. Understand how tyrosine and cysteine are synthesized from phenylalanine and methionine respectively. Test your knowledge on the synthesis of amino acids from ketoacids.

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