Study Designs in Comparative Effectiveness Research

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What is a major limitation of observational studies in comparative effectiveness research?

They reflect real-world practice accurately

They do not provide real-world data

They rely heavily on individual study quality (correct)

They are not prone to biases

Which aspect of evidence-based healthcare decisions does CER NOT influence?

Formulary management

Development of treatment guidelines (correct)

Resource allocation optimization

Health policy decisions

How do systematic reviews/meta-analyses summarize evidence in comparative effectiveness research?

By relying on biased data sources

By summarizing evidence from multiple studies (correct)

By excluding conflicting findings

By ignoring the quality of individual studies

What is a common ethical challenge faced in comparative effectiveness research?

Conflict of interest issues Signup and view all the answers

Which study design provides strong evidence but may not reflect real-world practice?

Randomized controlled trials Signup and view all the answers

How does CER contribute to enhancing the value of healthcare interventions?

By improving patient outcomes Signup and view all the answers

Which of the following is NOT a potential source of bias in research findings according to the passage?

Researcher's personal beliefs Signup and view all the answers

What does the concept of 'generalizability' refer to in the context of the passage?

The applicability of study results to broader populations and real-world settings Signup and view all the answers

What is the primary purpose of New User Design (NUD) according to the learning objectives?

All of the above Signup and view all the answers

Which of the following study designs is NOT mentioned in the learning objectives as being used in NUD?

Randomized controlled trials Signup and view all the answers

What is the main challenge in implementing NUD according to the learning objectives?

Data access, privacy protection, and integration of electronic health records Signup and view all the answers

How does NUD complement pre-market clinical trials according to the learning objectives?

By generating real-world evidence and post-marketing surveillance Signup and view all the answers

Which of the following is NOT a key element of comparative effectiveness research (CER)?

Clinical terminologies like CTV3 and Read Codes Signup and view all the answers

Which of the following is NOT a potential data source for comparative effectiveness research?

SNOMED CT terminology Signup and view all the answers

Which of the following is NOT a primary role of comparative effectiveness research?

Conducting basic research on disease mechanisms Signup and view all the answers

Which of the following is a potential challenge or ethical consideration associated with comparative effectiveness research?

All of the above Signup and view all the answers

Which of the following is NOT a potential outcome measure in comparative effectiveness research?

Basic research findings on disease mechanisms Signup and view all the answers

Which of the following statements about comparative effectiveness research is INCORRECT?

It is focused on assessing interventions under ideal conditions, like efficacy trials. Signup and view all the answers