Study Designs in Comparative Effectiveness Research
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Questions and Answers

What is a major limitation of observational studies in comparative effectiveness research?

  • They reflect real-world practice accurately
  • They do not provide real-world data
  • They rely heavily on individual study quality (correct)
  • They are not prone to biases

    • Which aspect of evidence-based healthcare decisions does CER NOT influence?

  • Formulary management
  • Development of treatment guidelines (correct)
  • Resource allocation optimization
  • Health policy decisions

    • How do systematic reviews/meta-analyses summarize evidence in comparative effectiveness research?

  • By relying on biased data sources
  • By summarizing evidence from multiple studies (correct)
  • By excluding conflicting findings
  • By ignoring the quality of individual studies

    • What is a common ethical challenge faced in comparative effectiveness research?

    <p>Conflict of interest issues</p> Signup and view all the answers

    Which study design provides strong evidence but may not reflect real-world practice?

    <p>Randomized controlled trials</p> Signup and view all the answers

    How does CER contribute to enhancing the value of healthcare interventions?

    <p>By improving patient outcomes</p> Signup and view all the answers

    Which of the following is NOT a potential source of bias in research findings according to the passage?

    <p>Researcher's personal beliefs</p> Signup and view all the answers

    What does the concept of 'generalizability' refer to in the context of the passage?

    <p>The applicability of study results to broader populations and real-world settings</p> Signup and view all the answers

    What is the primary purpose of New User Design (NUD) according to the learning objectives?

    <p>All of the above</p> Signup and view all the answers

    Which of the following study designs is NOT mentioned in the learning objectives as being used in NUD?

    <p>Randomized controlled trials</p> Signup and view all the answers

    What is the main challenge in implementing NUD according to the learning objectives?

    <p>Data access, privacy protection, and integration of electronic health records</p> Signup and view all the answers

    How does NUD complement pre-market clinical trials according to the learning objectives?

    <p>By generating real-world evidence and post-marketing surveillance</p> Signup and view all the answers

    Which of the following is NOT a key element of comparative effectiveness research (CER)?

    <p>Clinical terminologies like CTV3 and Read Codes</p> Signup and view all the answers

    Which of the following is NOT a potential data source for comparative effectiveness research?

    <p>SNOMED CT terminology</p> Signup and view all the answers

    Which of the following is NOT a primary role of comparative effectiveness research?

    <p>Conducting basic research on disease mechanisms</p> Signup and view all the answers

    Which of the following is a potential challenge or ethical consideration associated with comparative effectiveness research?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is NOT a potential outcome measure in comparative effectiveness research?

    <p>Basic research findings on disease mechanisms</p> Signup and view all the answers

    Which of the following statements about comparative effectiveness research is INCORRECT?

    <p>It is focused on assessing interventions under ideal conditions, like efficacy trials.</p> Signup and view all the answers

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