Stenotrophomonas Genomics and Characteristics

Questions and Answers

Through the reduction of oxygen

Through the fermentation of glucose

Through the activation of microbial secretion systems and regulatory proteins (correct)

Through the production of lactose

Through the reagent water supply (correct)

Direct person-to-person contact

Through airborne transmission

Contamination of medical equipment

Soil and water (correct)

Human gut

Human skin

Human respiratory tract

6.1% to 90% Signup and view all the answers

It identifies the genetic mechanisms of Stenotrophomonas virulence factors Signup and view all the answers

Its antimicrobial resistance profile Signup and view all the answers

Study Notes

The whole genome shotgun sequence of S.maltophilia strain K279a, the first Stenotrophomonas species isolated from a cystic fibrosis patient, has been determined.
64 validated genes support molecular mechanisms involved in pathogenesis and virulence of Stenotrophomonas spp.
Identified genes encode for microbial secretion systems and regulatory proteins involved in bacterial adhesion, colonization, and intracellular growth.

Stenotrophomonas is an aerobic, nonfermentative, lactose-negative, oxidase-negative, catalase-positive, non-glucose-fermenting Gram-negative bacillus.
It belongs to the family Xanthomonadaceae.

Stenotrophomonas has a worldwide distribution and is present in soil and water, suggesting low pathogenic potential in humans.
It is a colonizer of the oropharynx, skin, and feces, with an isolation rate ranging from 6.1% to over 90% of patients with cystic fibrosis.
Contamination of reagent water supply or increase in source transmission and/or outbreaks in healthcare facilities has been reported.
Nosocomial spread is not common due to Stenotrophomonas' antimicrobial resistance profile.