Skin Cancer Epidemiology

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What type of epithelium is the epidermis composed of?

Pseudostratified columnar epithelium

Stratified columnar epithelium

Simple cuboidal epithelium

Specialised stratified squamous epithelium (correct)

What is the main function of the keratinocytes in the epidermis?

To produce sebum

To produce melanin

To regulate body temperature

To provide a barrier against trauma and infection (correct)

What is the name of the protein produced by keratinocytes in the granular layer?

Loricrin

Keratin

Melanin

Filaggrin (correct)

What is the purpose of hemidesmosomes in the epidermis?

To connect the epidermis to the basement membrane Signup and view all the answers

What is the name of the layer where stem cells are found in the epidermis?

Basal layer Signup and view all the answers

What is the name of the protein produced by melanocytes?

Melanin Signup and view all the answers

What is the function of Langerhans cells in the epidermis?

To regulate immune responses Signup and view all the answers

What is the name of the protein that anchors the epidermis to the basement membrane?

Integrin-α6 Signup and view all the answers

Why is registration of NMSC not mandatory in some countries?

Because only the first case in a patient is registered Signup and view all the answers

What is associated with the highest risk of UV radiation in England?

South west Signup and view all the answers

Which of the following is a characteristic of SCC?

More common in females on the legs Signup and view all the answers

What is important to observe when examining a skin lesion?

The 5 S's Signup and view all the answers

Why is early referral important for patients with skin conditions?

For identification and quick treatment Signup and view all the answers

What is important for dental practitioners to understand when managing patients with skin conditions?

The impact of skin conditions on oral health Signup and view all the answers

What should you be able to do by the end of this session?

Describe normal human skin and its role in homeostasis Signup and view all the answers

What is the skin structure that plays a role in homeostasis?

Epidermis Signup and view all the answers

What type of receptors are found in the skin for different modalities?

Specialized Signup and view all the answers

Where are the primary cutaneous nerve branches located?

Hypodermis Signup and view all the answers

What triggers the activation of cutaneous receptors?

Changes in body temperature Signup and view all the answers

What happens to the epidermis as a person ages?

It becomes thinner Signup and view all the answers

What happens to the number of melanocytes as a person ages?

It decreases Signup and view all the answers

Why does the skin of an older person have a reduced tolerance to sun exposure?

Due to decreased melanin production Signup and view all the answers

What happens to the subcutaneous fat as a person ages?

It decreases Signup and view all the answers

Why does an older person tend to overheat?

Due to decreased sweat gland activity Signup and view all the answers

What is the primary target of UVB radiation in the skin?

Epidermis Signup and view all the answers

What type of skin cancer originates most frequently in sun-exposed areas of the skin?

Non-melanoma skin cancer (NMSC) Signup and view all the answers

What is the wavelength range of UVA radiation?

320-400 nm Signup and view all the answers

What is the name of the type of skin cancer that is also known as in situ?

Bowen's disease Signup and view all the answers

What is the estimated percentage of malignancies in white populations caused by non-melanoma skin cancers?

20% Signup and view all the answers

Why are incidence rates of non-melanoma skin cancers often underestimated?

Policies for recording NMSC vary between countries Signup and view all the answers

What is the layer of skin that is primarily affected by UVA radiation?

Dermis Signup and view all the answers

What is the type of skin cancer that is the most common form of cancer in humans?

Non-melanoma skin cancer (NMSC) Signup and view all the answers

What is the main function of the hypodermis?

To insulate the body and serve as an energy supply Signup and view all the answers

What is the function of erector pili muscles?

To contract and cause 'goosebumps' Signup and view all the answers

What type of secretion does the sebaceous gland produce?

Oily and protein-rich Signup and view all the answers

What is the difference between apocrine and eccrine sweat glands?

Apocrine glands are associated with hair follicles, while eccrine glands are not Signup and view all the answers

What is the characteristic of sebaceous gland secretion?

It is stimulated by androgens and inhibited by estrogen Signup and view all the answers

What is unique about apocrine glands in women?

Their secretions undergo cyclical changes under the influence of the menstrual cycle hormones Signup and view all the answers

What is the function of apocrine glands?

To produce oily and protein-rich secretions Signup and view all the answers

When do apocrine glands become functional?

During puberty Signup and view all the answers