Skin as a Barrier and Tumor Promotion Quiz
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Questions and Answers

What is required for chemical haptens to induce sensitization?

  • Presence in the bloodstream
  • Activation of type 1 T-helper cells
  • Interaction with Langerhans cells
  • Attachment to carrier proteins (correct)

Which cells process complete antigens and present them to type 1 T-helper cells in regional lymph nodes?

  • Platelets
  • Macrophages
  • B-cells
  • Langerhans cells (correct)

What characterizes the immune response upon subsequent exposure to the same antigen after sensitization?

  • Dermal infiltration and spongiosis (correct)
  • Reduced inflammation
  • Enhanced oxygen absorption
  • Increased blood clotting

Which of the following is NOT a common contact allergen listed in the text?

<p>Penicillin (B)</p> Signup and view all the answers

Which substance found in some mouthwashes is listed as a common contact allergen?

<p>Chlorhexidine (C)</p> Signup and view all the answers

What adverse skin reaction can be caused by Thimerosal (Merthiolate) according to the text?

<p>Contact dermatitis (D)</p> Signup and view all the answers

What is the primary factor that determines the severity of a chemical burn?

<p>The reactivity and corrosiveness of the chemical (C)</p> Signup and view all the answers

Which type of burn can occur when necrotic tissue acts as a chemical reservoir, leading to continued cutaneous damage or systemic injury?

<p>Third-degree burn (A)</p> Signup and view all the answers

What is the recommended action for an acid spill on the skin?

<p>Flush with water to remove any remaining remnants (C)</p> Signup and view all the answers

Which type of dermatitis is a delayed (T-cell mediated) hypersensitive reaction?

<p>Allergic contact dermatitis (B)</p> Signup and view all the answers

Which anatomic site is considered the most sensitive to irritants?

<p>The eyelids (D)</p> Signup and view all the answers

Which individuals are considered the most sensitive to irritant dermatitis?

<p>Atopic individuals (D)</p> Signup and view all the answers

What type of hypersensitivity reaction is photoallergy?

<p>Type IV (D)</p> Signup and view all the answers

What is required for photoallergy to occur?

<p>Prior sensitization to the chemical (C)</p> Signup and view all the answers

What is the mechanism behind photoallergy and allergic contact dermatitis?

<p>UV light converts a potential photosensitizing chemical into a hapten that elicits an allergic response (D)</p> Signup and view all the answers

What type of hypersensitivity reaction causes urticaria?

<p>Type I (D)</p> Signup and view all the answers

What is the cause of seasonal urticaria?

<p>Unknown (C)</p> Signup and view all the answers

What can cause exogenous hyperpigmentation?

<p>Deposition of metals and drugs in dermal tissue (C)</p> Signup and view all the answers

What is the most evident acute feature of UV radiation exposure?

<p>Erythema (redness or sunburn) (D)</p> Signup and view all the answers

Which of the following environmental conditions does NOT affect UV-induced injury?

<p>Humidity levels (D)</p> Signup and view all the answers

Which of the following is NOT listed as a characteristic skin change induced by chronic exposure to radiation?

<p>Skin dryness (C)</p> Signup and view all the answers

What types of malignant skin lesions are mentioned as resulting from chronic exposure to radiation?

<p>Basal cell carcinomas, squamous cell carcinomas, and malignant melanoma (B)</p> Signup and view all the answers

What type of ultraviolet light is most commonly responsible for acute phototoxic reactions?

<p>UVA (320 to 400 nm) (D)</p> Signup and view all the answers

Which of the following statements about phototoxic reactions is NOT true?

<p>UVB is solely responsible for phototoxic reactions (D)</p> Signup and view all the answers

What is the primary function of the skin in relation to xenobiotics and pollutants?

<p>Serving as a barrier against external insults (D)</p> Signup and view all the answers

How does the skin help in temperature regulation?

<p>Via sweating to cool down the body (D)</p> Signup and view all the answers

Which of the following is NOT a function of the skin as explained in the text?

<p>Digestion of food particles (C)</p> Signup and view all the answers

How does the skin protect from microbes according to the text?

<p>By using defensive mechanisms to prevent microbial entry (D)</p> Signup and view all the answers

What happens when the skin reacts to noxious physical agents?

<p>Coagulation cascade to prevent further bleeding (C)</p> Signup and view all the answers

How does the skin respond to deep cuts like from knives according to the text?

<p>Resisting penetration unless with significant impact (D)</p> Signup and view all the answers

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