Skin Barrier Function and Lipid Layer
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Questions and Answers

What role do ceramides play in the skin?

  • They act as a barrier against UV radiation.
  • They hold the skin together and prevent water loss. (correct)
  • They promote skin elasticity.
  • They regulate the skin's pH.

Which of the following can damage the skin barrier?

  • Regular moisturizers
  • Mild soaps
  • Harsh chemicals and soaps (correct)
  • Hydrating lotions

What is one method by which substances can enter the skin more effectively?

  • Patting the skin dry immediately
  • Application through massage (correct)
  • Using cold water
  • Rubbing with a coarse towel

Which of the following is NOT a function of the integumentary system?

<p>Hormone production (B)</p> Signup and view all the answers

What effect does over-washing have on the skin?

<p>Alters skin pH (B)</p> Signup and view all the answers

Flashcards

Skin Barrier

A protective barrier made of interwoven proteins that prevents water loss and external substances from entering.

Ceramides

A waxy lipid molecule that helps hold the skin together, preventing water loss and keeping it hydrated.

Cholesterol in Skin

A fatty molecule that helps create an impermeable barrier to harmful substances while allowing essential compounds to pass through.

Free Fatty Acids in Skin

Long-chain molecules that help regulate pH, lubricate the skin, and maintain its smoothness.

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Integumentary System

A complex system that protects the body, regulates temperature, provides sensation, and produces vitamin D.

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Study Notes

Skin Barrier Function

  • Skin acts as a barrier, preventing essential fluids and nutrients from leaving
  • Controls passages into the skin
  • Comprised of a "crossed-linked layer of proteins" that protects the skin's barrier.
  • Contains a lipid layer crucial for skin integrity

Lipid Layer Components

  • Ceramides: Waxy lipid molecules that bind skin and prevent water loss
  • Cholesterol: Fatty molecule that is impermeable to harmful substances while allowing essential compounds to pass.
  • Free fatty acids: Long-chain molecules that regulate pH and maintain skin smoothness, providing lubrication.

Damaged Skin Barrier

  • A compromised lipid barrier can lead to alterations in skin pH
  • Harsh chemicals, excessive washing, and insufficient hydration/diet can damage the skin barrier
  • Conditions like skin disorders can directly impact the barrier's integrity

Substance Entry

  • Substances enter the skin through various methods:
    • Water (steam)
    • Soaps/detergents
    • Hairy areas
    • Shaved areas
    • Massage application
    • Charged compounds (require chemical penetrators)
    • Small molecules
    • Lipid compounds (enter faster than water-soluble compounds)

Factors Affecting Entry

  • Time
  • Dosage

Integumentary System Functions

  • Protection: Protects against external factors
  • Secretion: Releases substances, like sweat
  • Sensation: Detects touch, temperature, and pain
  • Heat Regulation: Maintains body temperature
  • Vitamin D Production: Aids in Vitamin D synthesis

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Description

Explore the critical role of the skin barrier in maintaining health and preventing moisture loss. Understand the components of the lipid layer, including ceramides, cholesterol, and free fatty acids, and how they contribute to skin integrity. This quiz also covers the effects of damage to the skin barrier and how substances enter the skin.

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