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Questions and Answers
What role do ceramides play in the skin?
What role do ceramides play in the skin?
Which of the following can damage the skin barrier?
Which of the following can damage the skin barrier?
What is one method by which substances can enter the skin more effectively?
What is one method by which substances can enter the skin more effectively?
Which of the following is NOT a function of the integumentary system?
Which of the following is NOT a function of the integumentary system?
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What effect does over-washing have on the skin?
What effect does over-washing have on the skin?
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Study Notes
Skin Barrier Function
- Skin acts as a barrier, preventing essential fluids and nutrients from leaving
- Controls passages into the skin
- Comprised of a "crossed-linked layer of proteins" that protects the skin's barrier.
- Contains a lipid layer crucial for skin integrity
Lipid Layer Components
- Ceramides: Waxy lipid molecules that bind skin and prevent water loss
- Cholesterol: Fatty molecule that is impermeable to harmful substances while allowing essential compounds to pass.
- Free fatty acids: Long-chain molecules that regulate pH and maintain skin smoothness, providing lubrication.
Damaged Skin Barrier
- A compromised lipid barrier can lead to alterations in skin pH
- Harsh chemicals, excessive washing, and insufficient hydration/diet can damage the skin barrier
- Conditions like skin disorders can directly impact the barrier's integrity
Substance Entry
- Substances enter the skin through various methods:
- Water (steam)
- Soaps/detergents
- Hairy areas
- Shaved areas
- Massage application
- Charged compounds (require chemical penetrators)
- Small molecules
- Lipid compounds (enter faster than water-soluble compounds)
Factors Affecting Entry
- Time
- Dosage
Integumentary System Functions
- Protection: Protects against external factors
- Secretion: Releases substances, like sweat
- Sensation: Detects touch, temperature, and pain
- Heat Regulation: Maintains body temperature
- Vitamin D Production: Aids in Vitamin D synthesis
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Description
Explore the critical role of the skin barrier in maintaining health and preventing moisture loss. Understand the components of the lipid layer, including ceramides, cholesterol, and free fatty acids, and how they contribute to skin integrity. This quiz also covers the effects of damage to the skin barrier and how substances enter the skin.
