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Questions and Answers
What is the primary function of the phosphagen system?
Which of the following correctly describes the duration of ATP production via the phosphagen system?
What type of exercise primarily utilizes the anaerobic glycolysis system?
Which substrate is converted into pyruvate during glycolysis?
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Which statement about oxygen usage in energy systems is true?
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What is the primary function of the actin filament in a sarcomere?
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What is the role of troponin in muscle contraction?
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During which phase is a muscle the strongest?
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Which statement correctly describes the mechanism of an eccentric contraction?
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What is the significance of the Z band in a sarcomere?
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How many actin filaments surround each myosin filament in a sarcomere?
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What role does titin play in the muscle fiber?
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What structural component is known as a fascicle in skeletal muscle?
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What state are the Na+ gates in during the resting membrane potential?
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What initiates an action potential after a stimulus is received?
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During the depolarization phase, what is the state of the K+ gates?
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What happens to the Na+ gates during the repolarization phase?
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What ion movement occurs during hyperpolarization?
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What principle outlines that an action potential can only occur at a certain amplitude?
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What is the function of the absolute refractory period during repolarization?
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What describes the structural nature of myelin?
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What phase of muscle contraction is represented when a weight is raised during a bench press?
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Where are the cell bodies of alpha motor neurons located in the body?
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Which neurotransmitter is primarily responsible for synaptic transmission at the neuromuscular junction?
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What is the term for the maximum amount of weight that can be raised in a concentric phase?
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What is the role of action potentials in muscle contraction?
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Which contraction phase occurs when a weight is being lowered during a bench press?
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What physiological process occurs when neurotransmitters bind to the muscle cell membrane?
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What does a 1-repetition maximum test primarily measure?
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Which of the following correctly describes the P-R interval in the cardiac cycle?
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In Wigger’s Diagram, what does the aortic valve closing signify?
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Which cardiac arrhythmia is characterized by an irregular, often rapid heart rate due to chaotic electrical signals in the atria?
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What is the electrical event represented by the QRS complex in an electrocardiogram?
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What is the term for a heart rate that is faster than normal, opposite to bradycardia?
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What is the total number of ATP produced from 10 NADH molecules during cellular respiration?
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How many NADH are produced from one complete turn of the Krebs cycle?
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What is the correct stoichiometry for the creation of water in the electron transport chain?
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From pyruvate to acetyl Co-A, how many NADH molecules are generated?
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How many turns of the Krebs cycle occur for each molecule of glucose metabolized?
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How much ATP is produced from one FADH2 during the electron transport chain?
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Which hormone is primarily responsible for regulating blood glucose levels?
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What is the actual total ATP production for one glucose molecule after glycolysis, the Krebs cycle, and the electron transport chain?
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During glycolysis, how many ATP are used initially to convert glucose to pyruvate?
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What is the primary function of catecholamines?
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Which pair of hormones is involved in the regulation of stress and metabolism?
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Which hormone primarily contributes to the development of male secondary sexual characteristics?
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Which hormone is secreted in response to low blood glucose levels?
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What is the primary role of growth hormone in the body?
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Which hormone is primarily involved in maintaining fluid balance in the body?
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Which of the following is a primary function of epinephrine?
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Which of these hormones plays a role in both metabolism and the stress response?
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Which pair of hormones is commonly associated with the body's response to stress?
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What hormone is primarily responsible for increased sodium reabsorption and water retention during exercise?
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Which physiological response occurs when blood volume decreases due to fluid loss from exercise?
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What is the effect of angiotensin II following blood volume loss?
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Under what condition is erythropoietin released from the kidneys?
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What is the primary effect of aldosterone on kidney function?
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How does exercise influence blood pressure via hormonal responses?
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Which of the following mechanisms contributes to increased heart rate during exercise?
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What immediate effect does prolonged exercise have on blood composition?
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What does increased ADH release primarily promote in response to exercise?
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Which of the following statements about the effects of exercise on the cardiovascular system is true?
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What causes air to leave the lungs during expiration?
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What is the relationship between lung pressure and lung volume during expiration?
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How does pressure in the pleural space relate to lung pressure during a typical breath cycle?
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What occurs at the end of expiration in terms of pressure and lung volume?
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What effect does diaphragm relaxation have on lung dynamics during expiration?
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Which structure is responsible for the delivery of deoxygenated blood from the body back to the heart?
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What is the correct pathway of blood flow starting from the lungs?
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What does an electrocardiogram (ECG) primarily measure?
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Which heart valve separates the left atrium from the left ventricle?
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Which component is NOT part of the cardiovascular pathway of blood?
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Which of the following structures includes the valves that prevent backflow of blood in the heart?
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What is the function of pulmonary arteries in the circulatory system?
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What does the QRS complex in an ECG represent?
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Which of the following best describes the role of the aortic valve?
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Where is the electrical activity recorded in an electrocardiogram generated?
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Study Notes
Skeletal Muscle Anatomy and Function
- Skeletal muscle consists of fascicles, also known as bundles of muscle fibers (cells).
- Key components of muscle fiber: myofibrils and sarcomeres, which are the basic contractile units.
- Sarcomeres contain actin and myosin filaments, responsible for muscle contraction.
- The Z band defines the boundaries of each sarcomere.
Sarcomere Function
- Actin filaments slide during muscle contraction, aided by the mechanism of muscle proteins.
- Eccentric contractions involve slow relaxation of myosin heads and stretching of connective tissue forces.
- Each myosin has several actin filaments surrounding it, which enhances the interaction during contraction.
Muscle Strength Dynamics
- Muscles exhibit maximum strength in mid-range positions during contractions.
- Muscles are weakest when at extreme positions with no overlap of actin and myosin.
Range of Motion in Muscle Contraction
- Different phases of contraction include concentric (muscle shortening), isometric (muscle length stays constant), and eccentric (muscle lengthening).
- A 1-repetition maximum is defined as the heaviest weight that can be lifted in a single effort through a full range of motion.
Alpha Motor Neurons
- Cell bodies of motor neurons are located in the spinal cord.
- Action potentials facilitate communication between the brain and muscles, traveling along axons.
Synaptic Transmission
- Acetylcholine (Ach) is the neurotransmitter at the neuromuscular junction (NMJ).
- Binding of Ach to muscle membrane triggers depolarization, beginning an action potential in the muscle cell.
Action Potential Phases
- Resting Membrane Potential: Sodium (Na+) gates are closed; potassium (K+) gates also remain closed.
- Depolarization: Na+ gates open, allowing Na+ to flow into cells.
- Repolarization: Na+ gates inactivate, K+ gates open, allowing K+ to exit cells.
- Hyperpolarization: Na+ gates remain inactive; K+ gates open; ion movement stops after initial outflow.
All or None Principle
- The action potential exhibits an all-or-none response, with amplitude remaining constant.
- Variation in stimulus strength is achieved through the frequency of action potentials.
Energy Transfer Systems
- Three main energy systems:
- ATP-CP System: Provides immediate ATP via creatine phosphate, lasting 3-15 seconds without oxygen.
- Glycolysis: Converts glucose to pyruvate, playing a crucial role in both anaerobic and aerobic energy production.
Cardiac Physiology
- Wigger’s Diagram depicts cardiac cycle events including atrial depolarization (P wave) and ventricular depolarization (QRS complex).
- Cardiac arrhythmias can manifest as bradycardia, atrial fibrillation, ventricular tachycardia, and ventricular fibrillation.
- Bradycardia refers to abnormally slow heart rate, while tachycardia denotes an excessively fast pulse.
Practical Example: Exercise Dynamics
- Bench press showcases concentric, isometric, and eccentric contractions in a full range of motion.
Cellular Respiration Overview
- NAD+ is reduced to NADH during metabolic processes.
- Water is formed at the end of the Electron Transport Chain (ETC) through the reaction 2H + ½ O + 2e- → H2O.
Glycolysis
- Converts glucose to pyruvate.
- ATP consumption: 2 ATP.
- ATP production: 4 ATP (net gain: 2 ATP).
- NADH produced: 2 NADH.
Pyruvate to Acetyl CoA
- Produces 2 NADH.
Krebs Cycle (Citric Acid Cycle)
- Each cycle produces:
- 3 NADH
- 1 FADH2
- 1 ATP
- Each glucose undergoes 2 turns of the Krebs Cycle.
Electron Transport Chain Efficiency
- Each NADH yields approximately 2.5 ATP.
- Each FADH2 yields approximately 1.5 ATP.
Total ATP Production Calculation
- From 10 NADH: 2.5 x 10 = 25 ATP.
- From glycolysis: 2 ATP.
- From Pyruvate to Acetyl CoA: 2 NADH = 2 ATP.
- From Krebs cycle: 6 NADH = 15 ATP; 2 FADH2 = 3 ATP; total from Krebs cycle = 20 ATP.
- Overall, total ATP = 32 ATP.
Metabolism of Fat and Protein
- Enhanced water absorption and blood pressure during metabolism alters renal function.
- Increases Na+ reabsorption, causing potassium excretion, elevated heart rate, sympathetic nervous system activity, and aldosterone levels.
Water Retention Mechanism
- Exercise-induced fluid loss concentrates blood, reducing blood volume.
- Response includes:
- Increased ADH and renin release, leading to angiotensin II production.
- Angiotensin II causes vasoconstriction and increases aldosterone and ADH release, aiding water retention.
Erythropoietin Function
- Released from kidneys in response to low red blood cell count or hypoxia.
- Stimulates the production of red blood cells.
Catecholamines Role
- Involve neurotransmitters like epinephrine and norepinephrine, affecting various physiological responses.
Heart Anatomy and Blood Flow Pathway
- Know the chambers and valves of the heart.
- Blood flow pathway: Lungs → left atrium → left ventricle → aorta → arteries → arterioles → capillaries → venules → veins → vena cava → right atrium → right ventricle → lungs.
Electrocardiograph (ECG or EKG)
- Measures electrical activity of the heart.
- Records changes reflecting heart rhythm and potential abnormalities.
Respiratory Mechanics
- During expiration, pleural pressure changes inducing air to leave the lungs.
- Pressure in the pleural space decreases while lung volume increases and intrapleural pressure rises.
Summary of Pressure Changes
- At rest, pleural pressure and lung volume are balanced at 760 mmHg.
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Description
Test your knowledge on the anatomy and function of skeletal muscle with this quiz. Explore concepts including muscle fiber structure, sarcomere dynamics, and muscle strength during contractions. Perfect for students studying human anatomy or physiology.