29 Questions
What protein blocks the myosin binding sites on actin when the muscle is at rest?
Tropomyosin
Which protein senses rises in calcium concentration and forces tropomyosin to change its shape?
Troponin
What type of contraction occurs when a muscle shortens to do work?
Concentric contraction
Where do motor neurons innervate skeletal muscle tissue?
Sarcolemma of the muscle fiber
Which neurotransmitter is stored in the terminal boutons?
Acetylcholine
What is the center part of the A band where no thin filaments occur?
H zone
Which filaments are located in the center of the sarcomere?
Thick (myosin) filaments
What is the full length of the thick filament in a sarcomere called?
A band
During muscle contraction, which filaments interact with each other?
Both thin and thick filaments
Which component holds the thick filaments together at the center of the H zone?
M line
In which region of a sarcomere do thin filaments extend from Z disc toward the center?
Z disc
What is a muscle twitch?
An uncontrollable contraction of a small portion of a muscle
Which protein is affected in Duchenne muscular dystrophy (DMD)?
Dystrophin
What is the most common form of muscular dystrophy?
Duchenne muscular dystrophy (DMD)
What happens when the protein dystrophin is mutated in DMD?
The sarcolemma weakens and tears
What is the characteristic symptom onset age for Duchenne muscular dystrophy (DMD)?
Between 2 and 7 years
What causes pain in Myofascial Pain Syndrome?
Tightened bands of muscle fibers with trigger points
What are four functional properties that distinguish muscle tissue from other tissues?
Ability to contract, extensibility, elasticity, excitability
Which layers of connective tissue occur in and around skeletal muscle?
Endomysium, perimysium, epimysium, fascicles
Which symptoms are associated with myofascial pain syndrome?
Sharp or aching pain in muscles, trigger points, restricted movement
What are some symptoms commonly associated with delayed-onset muscle soreness?
Pain and stiffness 12-24 hours after intense exercise
How do muscles attach at their origins and insertions?
Through tendons attaching muscle to bone or cartilage
What is the primary tissue in the walls of hollow organs?
Smooth muscle tissue
Which prefix means 'muscle'?
Myo-
Which type of muscle tissue is responsible for maintaining posture and stabilizing joints?
Skeletal muscle tissue
What is the term for the plasma membrane of muscle cells?
Sarcolemma
Which type of muscle tissue has a 'fusiform' appearance?
Smooth muscle tissue
What is responsible for shortening muscle cells?
Myofilaments comprising actin or myosin proteins
Which type of muscle tissue is involuntary in nature?
Cardiac muscle tissue
Test your knowledge on the microscopic structure of skeletal muscle tissue, focusing on sarcomere organization, Z disc, thin and thick filaments, and muscle contraction. Understand the components like A bands, I bands, and how actin and myosin interact during muscle contraction.
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