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Questions and Answers

The first step in a signaling pathway that responds to a molecule that stays in the extracellular space is

  • binding of the signal molecule to a receptor. (correct)
  • diffusion through the plasma membrane into the cell.
  • activation of gene expression.
  • phosphorylation and activation of the receptor protein.

What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute?

  • one that involves the release of secretory vesicles
  • one that involves a change in gene expression (correct)
  • one that involves the firing of an action potential along a neuron
  • one that uses a phosphorylation event to activate an enzyme

Which of the following is NOT an intracellular signaling protein activated by an RTK?

  • Ras
  • monomeric GTPase
  • G-protein (correct)
  • PI-3-kinase

Steroid hormones trigger transcription of target genes by

<p>binding to nuclear receptors that act as transcription factors for specific genes. (B)</p> Signup and view all the answers

Which of the following types of cell signaling is long range and uses hormones as signals?

<p>endocrine (D)</p> Signup and view all the answers

The active form of a monomeric GTP-binding protein is the

<p>GTP-bound form. (A)</p> Signup and view all the answers

Which of the following describes negative feedback regulation?

<p>A component late in the pathway inhibits an enzyme early in the pathway. (A)</p> Signup and view all the answers

Enzymes that add a phosphate group to a switch protein are called

<p>kinases. (B)</p> Signup and view all the answers

How does the binding of a signal molecule activate an RTK for downstream signaling?

<p>The RTK forms a dimer and cross-phosphorylates itself. (B)</p> Signup and view all the answers

Shown below is a diagram of how theoretical intracellular signaling pathways could integrate incoming signals to produce a coordinated cell response.

<p>signals A and D (A)</p> Signup and view all the answers

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