SGLT2 Inhibitors Overview
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Questions and Answers

What is the mechanism of action of SGLT2 inhibitors?

  • Increases glucose reabsorption in the proximal tubule
  • Inhibits glucose reabsorption in the distal tubule (correct)
  • Promotes glucose excretion in the systemic system
  • Stimulates glucose reabsorption in the nephron

Which side effect is commonly associated with SGLT2 inhibitors?

  • Genitourinary infections (correct)
  • Hyperkalemia
  • Hypoglycemia
  • Hypercholesterolemia

What is the primary mechanism of action of Incretin mimetics?

  • Decreasing satiety
  • Decreasing insulin secretion
  • Increasing glucagon secretion
  • Decreasing gastric emptying rate (correct)

Which medication is associated with a risk of Medullary Thyroid Cancer (MTR) and Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2)?

<p>GLP-1/GIP agonist (D)</p> Signup and view all the answers

What is a common side effect of GLP-1/GIP agonists?

<p>Cholelithiasis (gallstones) (D)</p> Signup and view all the answers

How do SGLT2 inhibitors contribute to weight loss?

<p>By preventing glucose reabsorption into the systemic system (B)</p> Signup and view all the answers

What is the mechanism of action of Bile Acid Sequestrants in the context of glucose management?

<p>Inhibits the PEPCK enzyme to decrease gluconeogenesis (D)</p> Signup and view all the answers

Which medication can lead to a 'medical emergency' due to the risk of lactic acidosis?

<p>Thiazolidinediones (B)</p> Signup and view all the answers

Which medication is specifically known for inducing ovulation?

<p>Thiazolidinediones (C)</p> Signup and view all the answers

Which class of medications is associated with an increased risk of bladder cancer?

<p>Thiazolidinediones (A)</p> Signup and view all the answers

Which medication has the primary effect of inhibiting the DPP-4 enzyme?

<p>DPP-4 inhibitors (B)</p> Signup and view all the answers

What is the key mechanism by which Sulfonylureas induce insulin release from pancreatic beta cells?

<p>Binds to SU co-receptor of K channels and activates Ca influx into cells (B)</p> Signup and view all the answers

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