SGLT2 Inhibitors Overview
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Questions and Answers

What is the mechanism of action of SGLT2 inhibitors?

  • Increases glucose reabsorption in the proximal tubule
  • Inhibits glucose reabsorption in the distal tubule (correct)
  • Promotes glucose excretion in the systemic system
  • Stimulates glucose reabsorption in the nephron

    • Which side effect is commonly associated with SGLT2 inhibitors?

  • Genitourinary infections (correct)
  • Hyperkalemia
  • Hypoglycemia
  • Hypercholesterolemia

    • What is the primary mechanism of action of Incretin mimetics?

  • Decreasing satiety
  • Decreasing insulin secretion
  • Increasing glucagon secretion
  • Decreasing gastric emptying rate (correct)

    • Which medication is associated with a risk of Medullary Thyroid Cancer (MTR) and Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2)?

    <p>GLP-1/GIP agonist</p> Signup and view all the answers

    What is a common side effect of GLP-1/GIP agonists?

    <p>Cholelithiasis (gallstones)</p> Signup and view all the answers

    How do SGLT2 inhibitors contribute to weight loss?

    <p>By preventing glucose reabsorption into the systemic system</p> Signup and view all the answers

    What is the mechanism of action of Bile Acid Sequestrants in the context of glucose management?

    <p>Inhibits the PEPCK enzyme to decrease gluconeogenesis</p> Signup and view all the answers

    Which medication can lead to a 'medical emergency' due to the risk of lactic acidosis?

    <p>Thiazolidinediones</p> Signup and view all the answers

    Which medication is specifically known for inducing ovulation?

    <p>Thiazolidinediones</p> Signup and view all the answers

    Which class of medications is associated with an increased risk of bladder cancer?

    <p>Thiazolidinediones</p> Signup and view all the answers

    Which medication has the primary effect of inhibiting the DPP-4 enzyme?

    <p>DPP-4 inhibitors</p> Signup and view all the answers

    What is the key mechanism by which Sulfonylureas induce insulin release from pancreatic beta cells?

    <p>Binds to SU co-receptor of K channels and activates Ca influx into cells</p> Signup and view all the answers

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