12 Questions
What is the mechanism of action of SGLT2 inhibitors?
Inhibits glucose reabsorption in the distal tubule
Which side effect is commonly associated with SGLT2 inhibitors?
Genitourinary infections
What is the primary mechanism of action of Incretin mimetics?
Decreasing gastric emptying rate
Which medication is associated with a risk of Medullary Thyroid Cancer (MTR) and Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2)?
GLP-1/GIP agonist
What is a common side effect of GLP-1/GIP agonists?
Cholelithiasis (gallstones)
How do SGLT2 inhibitors contribute to weight loss?
By preventing glucose reabsorption into the systemic system
What is the mechanism of action of Bile Acid Sequestrants in the context of glucose management?
Inhibits the PEPCK enzyme to decrease gluconeogenesis
Which medication can lead to a 'medical emergency' due to the risk of lactic acidosis?
Thiazolidinediones
Which medication is specifically known for inducing ovulation?
Thiazolidinediones
Which class of medications is associated with an increased risk of bladder cancer?
Thiazolidinediones
Which medication has the primary effect of inhibiting the DPP-4 enzyme?
DPP-4 inhibitors
What is the key mechanism by which Sulfonylureas induce insulin release from pancreatic beta cells?
Binds to SU co-receptor of K channels and activates Ca influx into cells
Learn about the mechanism of action, side effects, and benefits of SGLT2 inhibitors, a class of medications that prevent glucose reabsorption in the kidneys. Topics covered include weight loss, blood pressure reduction, genitourinary infections, and other associated risks.
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