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Questions and Answers
What is the role of hyperglycemia in insulin secretion from beta cells?
What is the role of hyperglycemia in insulin secretion from beta cells?
- Increases glucose uptake in beta-cells (correct)
- Promotes opening of K+-channels on beta-cells
- Inhibits the release of pre-stored insulin
- Decreases ATP levels in beta-cells
Which of the following is an endogenous inhibitor of insulin secretion?
Which of the following is an endogenous inhibitor of insulin secretion?
- High faNy acids levels
- Chronically elevated glucose levels (correct)
- Exogenous insulin administration
- Beta-adrenergic sympathetic activity
What is the mechanism of insulin release from beta-cells?
What is the mechanism of insulin release from beta-cells?
- Increase in K+ efflux from beta-cells
- Opening of voltage-gated Ca2+ channels (correct)
- Suppression of ATP production
- Activating ATP-dependent K+-channels
Which class of medications promotes insulin secretion from beta-cells by blocking K+ efflux, leading to depolarization and subsequent Ca2+ influx?
Which class of medications promotes insulin secretion from beta-cells by blocking K+ efflux, leading to depolarization and subsequent Ca2+ influx?
Which class of medications is known for its fast onset, low duration, and lower risk for hypoglycemia due to their mechanism of action?
Which class of medications is known for its fast onset, low duration, and lower risk for hypoglycemia due to their mechanism of action?
Which of the following is true regarding chronic treatment with sulfonylureas?
Which of the following is true regarding chronic treatment with sulfonylureas?
Which mechanism describes how SGLT2 inhibitors reduce blood glucose levels?
Which mechanism describes how SGLT2 inhibitors reduce blood glucose levels?
What is a common adverse effect associated with SGLT2 inhibitors according to the text?
What is a common adverse effect associated with SGLT2 inhibitors according to the text?
Which statement is true regarding amylin in diabetes mellitus?
Which statement is true regarding amylin in diabetes mellitus?
What is the role of glucagon in the body?
What is the role of glucagon in the body?
What is the main effect of glucagon on insulin secretion?
What is the main effect of glucagon on insulin secretion?
What is the primary function of α-glucosidase inhibitors as described in the text?
What is the primary function of α-glucosidase inhibitors as described in the text?
What stimulates the secretion of glucagon?
What stimulates the secretion of glucagon?
What is the effect of glucagon on cAMP?
What is the effect of glucagon on cAMP?
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