Questions and Answers
What is the primary cause of Severe Combined Immunodeficiency (SCID)?
Genetic disorder affecting the body's ability to fight infections
What are the symptoms typically associated with SCID in infants?
Recurrent infections, difficulty gaining weight, and thrush
Which enzyme plays a crucial role in purine metabolism and its deficiency can lead to SCID?
Adenosine deaminase (ADA)
How was SCID traditionally treated?
Signup and view all the answers
Which cells are lacking in individuals with SCID?
Signup and view all the answers
How can gene expression regulate enzymes involved in purine metabolism?
Signup and view all the answers
Which disease is associated with abnormalities in nucleotide metabolism, leading to the accumulation of uric acid?
Signup and view all the answers
What is the role of post-translational modifications in purine metabolism?
Signup and view all the answers
How is uric acid formed in the context of nucleotide metabolism?
Signup and view all the answers
What is the primary function of allosteric regulation in purine metabolism?
Signup and view all the answers
Which molecule pairs with guanine to form the rungs of the DNA ladder?
Signup and view all the answers
What is the specific role of purines and pyrimidines in addition to their involvement in DNA and RNA?
Signup and view all the answers
Which nitrogenous base is larger and has a two-ring structure?
Signup and view all the answers
Which condition is associated with abnormalities in nucleotide metabolism, leading to the accumulation of uric acid?
Signup and view all the answers
What is the primary cause of Lesch-Nyhan syndrome?
Signup and view all the answers
