Seminoma Testicular Germ Cell Neoplasm Overview
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Questions and Answers

What is the most common testicular germ cell neoplasm?

  • Yolk sac tumor
  • Choriocarcinoma
  • Seminoma (correct)
  • Embryonal carcinoma

At what age does seminoma peak in terms of incidence?

  • 50-55 years
  • 20-25 years
  • 34-45 years (correct)
  • 30-35 years

What is a characteristic feature of seminomas on gross examination?

  • Soft, well-demarcated, gray-white tumors (correct)
  • Invasion into surrounding structures
  • Hemorrhage within the tumor
  • Bilateral involvement of the testes

Microscopically, how are seminomas characterized?

<p>Small lobules with fibrous septa (C)</p> Signup and view all the answers

What is a typical presentation of patients with seminoma?

<p>Asymptomatic scrotal mass (B)</p> Signup and view all the answers

Which hormone can be positively stained in as many as 25% of seminoma cases?

<p>Human chorionic gonadotropin (hCG) (D)</p> Signup and view all the answers

What is the age range in which embryonal carcinoma most frequently occurs?

<p>25-35 years (C)</p> Signup and view all the answers

Which of the following is a common clinical presentation of embryonal carcinoma?

<p>Painful unilateral enlarging testicular mass (D)</p> Signup and view all the answers

What is a characteristic microscopic feature of embryonal carcinoma cells?

<p>Prominent nucleoli and basophilic cytoplasm (D)</p> Signup and view all the answers

Which germ cell tumor is the most common primary testicular neoplasm in children younger than 3 years of age?

<p>Yolk sac tumor (B)</p> Signup and view all the answers

What histological feature is characteristic of yolk sac tumors (endodermal sinus tumors)?

<p>Presence of primitive glomeruli (Schiller-Duvall bodies) (D)</p> Signup and view all the answers

Which immunohistochemical marker can be demonstrated within the neoplastic cells in yolk sac tumors?

<p>Alpha-fetoprotein (AFP) (D)</p> Signup and view all the answers

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