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Seminoma Testicular Germ Cell Neoplasm Overview

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Seminoma Testicular Germ Cell Neoplasm Overview

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Questions and Answers

What is the most common testicular germ cell neoplasm?

Yolk sac tumor

Choriocarcinoma

Seminoma (correct)

Embryonal carcinoma

At what age does seminoma peak in terms of incidence?

50-55 years

20-25 years

34-45 years (correct)

30-35 years

What is a characteristic feature of seminomas on gross examination?

Soft, well-demarcated, gray-white tumors (correct)

Invasion into surrounding structures

Hemorrhage within the tumor

Bilateral involvement of the testes

Microscopically, how are seminomas characterized?

Small lobules with fibrous septa Signup and view all the answers

What is a typical presentation of patients with seminoma?

Asymptomatic scrotal mass Signup and view all the answers

Which hormone can be positively stained in as many as 25% of seminoma cases?

Human chorionic gonadotropin (hCG) Signup and view all the answers

What is the age range in which embryonal carcinoma most frequently occurs?

25-35 years Signup and view all the answers

Which of the following is a common clinical presentation of embryonal carcinoma?

Painful unilateral enlarging testicular mass Signup and view all the answers

What is a characteristic microscopic feature of embryonal carcinoma cells?

Prominent nucleoli and basophilic cytoplasm Signup and view all the answers

Which germ cell tumor is the most common primary testicular neoplasm in children younger than 3 years of age?

Yolk sac tumor Signup and view all the answers

What histological feature is characteristic of yolk sac tumors (endodermal sinus tumors)?

Presence of primitive glomeruli (Schiller-Duvall bodies) Signup and view all the answers

Which immunohistochemical marker can be demonstrated within the neoplastic cells in yolk sac tumors?

Alpha-fetoprotein (AFP) Signup and view all the answers