12 Questions
What is the peak incidence age range for seminoma?
34-45 years
Which of the following is a common gross feature of seminomas?
Soft, well-demarcated, gray-white tumors
At what age range is seminoma extremely rare, especially in children younger than 5 years?
0-10 years
What is a characteristic microscopic feature of seminomas?
Large, uniform cells with clear cytoplasm and round nuclei
What is a possible diagnostic feature of seminomas in terms of staining?
Positive staining for human chorionic gonadotropin (hCG)
What is a common accompanying feature microscopically in seminomas?
Granulomatous inflammatory reaction
What is the most common age range for embryonal carcinoma?
25-35 years
Which of the following is a common presenting symptom of patients with embryonal carcinoma?
Painless unilateral enlarging testicular mass
What is a common feature of embryonal carcinoma when observed microscopically?
Large cells with basophilic cytoplasm and prominent nucleoli
Which tumor is the most common primary testicular neoplasm in children younger than 3 years of age?
Yolk sac tumor (endodermal sinus tumor)
What distinctive feature is present in yolk sac tumors microscopically?
Primitive glomeruli structures resembling Schiller-Duvall bodies
Which immunohistochemical marker can be detected within the neoplastic cells of yolk sac tumors?
α-fetoprotein (AFP)
Learn about the characteristics and incidence of seminoma, the most common testicular germ cell neoplasm. Understand its peak incidence age range, presentation, gross features, and rarity in children.
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