Seminoma: Testicular Germ Cell Neoplasm
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Questions and Answers

What is the peak incidence age range for seminoma?

  • 40-50 years
  • 34-45 years (correct)
  • 20-30 years
  • 25-35 years
  • Which of the following is a common gross feature of seminomas?

  • Tumors with diffuse invasion into surrounding tissues
  • Hard, ill-defined, and multicolored tumors
  • Soft, well-demarcated, gray-white tumors (correct)
  • Tumors with hemorrhage and no necrosis
  • At what age range is seminoma extremely rare, especially in children younger than 5 years?

  • 15-25 years
  • 10-20 years
  • 0-10 years (correct)
  • 5-15 years
  • What is a characteristic microscopic feature of seminomas?

    <p>Large, uniform cells with clear cytoplasm and round nuclei</p> Signup and view all the answers

    What is a possible diagnostic feature of seminomas in terms of staining?

    <p>Positive staining for human chorionic gonadotropin (hCG)</p> Signup and view all the answers

    What is a common accompanying feature microscopically in seminomas?

    <p>Granulomatous inflammatory reaction</p> Signup and view all the answers

    What is the most common age range for embryonal carcinoma?

    <p>25-35 years</p> Signup and view all the answers

    Which of the following is a common presenting symptom of patients with embryonal carcinoma?

    <p>Painless unilateral enlarging testicular mass</p> Signup and view all the answers

    What is a common feature of embryonal carcinoma when observed microscopically?

    <p>Large cells with basophilic cytoplasm and prominent nucleoli</p> Signup and view all the answers

    Which tumor is the most common primary testicular neoplasm in children younger than 3 years of age?

    <p>Yolk sac tumor (endodermal sinus tumor)</p> Signup and view all the answers

    What distinctive feature is present in yolk sac tumors microscopically?

    <p>Primitive glomeruli structures resembling Schiller-Duvall bodies</p> Signup and view all the answers

    Which immunohistochemical marker can be detected within the neoplastic cells of yolk sac tumors?

    <p>α-fetoprotein (AFP)</p> Signup and view all the answers

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