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Questions and Answers
What is the primary function of the kidneys in regulating fluid and electrolyte balance?
What is the primary function of the kidneys in regulating fluid and electrolyte balance?
What is the term used to describe the abrupt decrease in kidney function, resulting in the retention of urea and other nitrogenous waste products?
What is the term used to describe the abrupt decrease in kidney function, resulting in the retention of urea and other nitrogenous waste products?
What is the percentage of filtrate that is reabsorbed by the kidneys in an average adult?
What is the percentage of filtrate that is reabsorbed by the kidneys in an average adult?
What is the term used to describe the accumulation of nitrogen waste products in the blood?
What is the term used to describe the accumulation of nitrogen waste products in the blood?
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What is the term used to describe the classification system for AKI that uses serum creatinine, glomerular filtration rate (GFR), and urine output?
What is the term used to describe the classification system for AKI that uses serum creatinine, glomerular filtration rate (GFR), and urine output?
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What is the age-related change that increases the risk of developing AKI in older persons?
What is the age-related change that increases the risk of developing AKI in older persons?
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What is the term used to describe the type of AKI that is due to inadequate renal perfusion?
What is the term used to describe the type of AKI that is due to inadequate renal perfusion?
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What is the percentage of critical care unit (CCU) patients that develop severe AKI?
What is the percentage of critical care unit (CCU) patients that develop severe AKI?
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What is the term used to describe the process that aids in maintaining normal plasma osmolality, electrolyte balance, blood volume, and acid-base balance?
What is the term used to describe the process that aids in maintaining normal plasma osmolality, electrolyte balance, blood volume, and acid-base balance?
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What is the typical range of urine output per day during the oliguric phase of acute kidney injury?
What is the typical range of urine output per day during the oliguric phase of acute kidney injury?
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Which of the following is NOT a typical symptom of uremia in acute kidney injury?
Which of the following is NOT a typical symptom of uremia in acute kidney injury?
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Which of the following is a possible physical finding in a patient with uremic pericarditis?
Which of the following is a possible physical finding in a patient with uremic pericarditis?
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What is the primary cause of decreased renal blood flow within 3 to 4 hours after an obstruction of the urinary tract?
What is the primary cause of decreased renal blood flow within 3 to 4 hours after an obstruction of the urinary tract?
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What is the typical urine output in the prodromal phase of acute kidney injury?
What is the typical urine output in the prodromal phase of acute kidney injury?
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What is a characteristic of the postoliguric phase in acute kidney injury?
What is a characteristic of the postoliguric phase in acute kidney injury?
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Which of the following situations is likely to cause significant acute kidney injury?
Which of the following situations is likely to cause significant acute kidney injury?
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What is an important part of the diagnosis of acute kidney injury?
What is an important part of the diagnosis of acute kidney injury?
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What is the most common cause of sudden cessation of urinary output in men?
What is the most common cause of sudden cessation of urinary output in men?
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What may be a complication of acute kidney injury?
What may be a complication of acute kidney injury?
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Which of the following is a possible manifestation of fluid accumulation in the lungs due to acute kidney injury?
Which of the following is a possible manifestation of fluid accumulation in the lungs due to acute kidney injury?
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What is a priority when determining the cause of acute kidney injury?
What is a priority when determining the cause of acute kidney injury?
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What is a characteristic of prerenal acute kidney injury?
What is a characteristic of prerenal acute kidney injury?
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What is a treatment for prerenal acute kidney injury?
What is a treatment for prerenal acute kidney injury?
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What is a laboratory test used to diagnose acute kidney injury?
What is a laboratory test used to diagnose acute kidney injury?
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What is a physical finding that may be seen in acute kidney injury?
What is a physical finding that may be seen in acute kidney injury?
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A patient presents with anuria, peripheral edema, and a history of an enlarged prostate. Which of the following is the most likely cause of the patient's acute kidney injury?
A patient presents with anuria, peripheral edema, and a history of an enlarged prostate. Which of the following is the most likely cause of the patient's acute kidney injury?
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A patient with acute kidney injury (AKI) is in the oliguric phase. What is the typical range of urine output per day in this phase?
A patient with acute kidney injury (AKI) is in the oliguric phase. What is the typical range of urine output per day in this phase?
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Which of the following is a potential complication of AKI that can cause chest pain, pericardial friction rub, and findings of pericardial tamponade?
Which of the following is a potential complication of AKI that can cause chest pain, pericardial friction rub, and findings of pericardial tamponade?
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A patient with AKI presents with asterixis and hyperreflexia. These findings are most likely indicative of:
A patient with AKI presents with asterixis and hyperreflexia. These findings are most likely indicative of:
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A patient with AKI has a urine output of 200 mL/day. What phase of AKI is the patient most likely in?
A patient with AKI has a urine output of 200 mL/day. What phase of AKI is the patient most likely in?
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A patient with bilateral ureteral obstruction is at risk for which type of AKI?
A patient with bilateral ureteral obstruction is at risk for which type of AKI?
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Which of the following is a common symptom of uremia in AKI?
Which of the following is a common symptom of uremia in AKI?
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What is the typical duration of the oliguric phase of AKI?
What is the typical duration of the oliguric phase of AKI?
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How is the postoliguric phase characterized in patients with acute kidney injury?
How is the postoliguric phase characterized in patients with acute kidney injury?
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What is a common laboratory finding in acute kidney injury related to electrolytes?
What is a common laboratory finding in acute kidney injury related to electrolytes?
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Which of the following is a reversible cause of acute kidney injury that should be prioritized in diagnosis?
Which of the following is a reversible cause of acute kidney injury that should be prioritized in diagnosis?
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Which treatment approach is typically appropriate for prerenal acute kidney injury caused by hypovolemia?
Which treatment approach is typically appropriate for prerenal acute kidney injury caused by hypovolemia?
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What physical finding is commonly associated with acute kidney injury and may indicate fluid overload?
What physical finding is commonly associated with acute kidney injury and may indicate fluid overload?
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Which of the following electrolyte imbalances is typically seen with acute kidney injury due to renal dysfunction?
Which of the following electrolyte imbalances is typically seen with acute kidney injury due to renal dysfunction?
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Which assessment is crucial in diagnosing the cause of acute kidney injury?
Which assessment is crucial in diagnosing the cause of acute kidney injury?
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What laboratory test would be least helpful in diagnosing acute kidney injury?
What laboratory test would be least helpful in diagnosing acute kidney injury?
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Which of the following is a classification system used to determine the severity of acute kidney injury (AKI)?
Which of the following is a classification system used to determine the severity of acute kidney injury (AKI)?
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Which of the following is a common cause of prerenal acute kidney injury?
Which of the following is a common cause of prerenal acute kidney injury?
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Which of the following is a hallmark sign of acute kidney injury (AKI)?
Which of the following is a hallmark sign of acute kidney injury (AKI)?
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Which of the following is a possible complication of acute kidney injury (AKI)?
Which of the following is a possible complication of acute kidney injury (AKI)?
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Which of the following is a nursing intervention for a patient with acute kidney injury (AKI)?
Which of the following is a nursing intervention for a patient with acute kidney injury (AKI)?
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Which of the following is a nursing assessment finding that may indicate acute kidney injury (AKI)?
Which of the following is a nursing assessment finding that may indicate acute kidney injury (AKI)?
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Which of the following is a classification of burns based on depth of tissue involvement?
Which of the following is a classification of burns based on depth of tissue involvement?
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Which of the following is the most common type of burn?
Which of the following is the most common type of burn?
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Which of the following is a nursing intervention for a patient with a burn?
Which of the following is a nursing intervention for a patient with a burn?
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According to the rule of nines, what percentage of the body surface area is affected by a burn that covers the entire right arm?
According to the rule of nines, what percentage of the body surface area is affected by a burn that covers the entire right arm?
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Study Notes
Acute Kidney Injury (AKI)
- Defined as a rapid decline in kidney function leading to nitrogenous waste retention and electrolyte imbalance.
- Replaced the term acute renal failure (ARF) to emphasize smaller declines in function that increase morbidity and mortality.
- Essential kidneys functions include regulating fluid and electrolytes and maintaining water balance through urine volume adjustments.
Kidney Function
- Adult kidneys filter total plasma volume multiple times daily, reabsorbing approximately 99% of filtrate, resulting in about 1.5 liters of urine daily.
- Urine formation occurs in renal tubules involving selective reabsorption and secretion of water and electrolytes.
- Plays a critical role in maintaining plasma osmolality, electrolyte balance, blood volume, and acid-base homeostasis, influenced by ADH and aldosterone.
Diagnostic Criteria for AKI
- Diagnosis involves assessing acute reductions in urine output and elevations in serum creatinine, potentially leading to azotemia.
- Untreated AKI can result in fluid overload, electrolyte imbalances, metabolic acidosis, and increased mortality risk from infections.
Causes and Risk Factors
- Severe AKI may arise from prolonged hypotension, hypovolemia, or nephrotoxic agents, developing over hours or days.
- Critically ill patients exhibit severe AKI in over 60% of cases with mortality rates reaching 70-80%.
- Classification of AKI includes prerenal, renal, and postrenal causes.
Age and Susceptibility
- Older adults are more vulnerable to AKI due to a natural decline in functional nephrons and concurrent organ system impairments.
- Aging kidneys are less capable of handling changes in fluid volume and cardiac output.
Classification of AKI Causes
- Prerenal AKI leads to inadequate renal perfusion; patients often experience lower morbidity and mortality.
- Nonoliguric patients may develop a postoliguric phase, gradually returning urine output to normal while serum creatinine levels may remain elevated temporarily.
Diagnostic Approaches
- Diagnostic evaluations include clinical assessments, medication reviews, and laboratory tests such as CBC, BUN, serum creatinine, and urinalysis.
- Imaging studies like renal ultrasound may be used for suspected postrenal causes.
Laboratory Results in AKI
- Common findings include acidosis, hyperkalemia, hyponatremia, anemia, hyperphosphatemia, and hypocalcemia.
Management and Treatment
- Immediate focus involves identifying and reversing treatable causes like volume depletion or obstruction.
- Prerenal AKI management may include volume infusion in cases of hypovolemia, while obstructive causes require resolution of the underlying obstruction.
- Initial observations may indicate weight gain and edemas, with symptoms of uremia such as anorexia, nausea, weakness, and confusion developing later.
Phases of Urine Output in AKI
- The prodromal phase usually has normal urine output of variable duration based on underlying factors.
- The oliguric phase is characterized by urine output between 50-500 mL/day; its duration is highly variable, contingent on the AKI's cause and treatment timeline.
Acute Kidney Injury (AKI)
- Defined as a rapid decline in kidney function leading to nitrogenous waste retention and electrolyte imbalance.
- Replaced the term acute renal failure (ARF) to emphasize smaller declines in function that increase morbidity and mortality.
- Essential kidneys functions include regulating fluid and electrolytes and maintaining water balance through urine volume adjustments.
Kidney Function
- Adult kidneys filter total plasma volume multiple times daily, reabsorbing approximately 99% of filtrate, resulting in about 1.5 liters of urine daily.
- Urine formation occurs in renal tubules involving selective reabsorption and secretion of water and electrolytes.
- Plays a critical role in maintaining plasma osmolality, electrolyte balance, blood volume, and acid-base homeostasis, influenced by ADH and aldosterone.
Diagnostic Criteria for AKI
- Diagnosis involves assessing acute reductions in urine output and elevations in serum creatinine, potentially leading to azotemia.
- Untreated AKI can result in fluid overload, electrolyte imbalances, metabolic acidosis, and increased mortality risk from infections.
Causes and Risk Factors
- Severe AKI may arise from prolonged hypotension, hypovolemia, or nephrotoxic agents, developing over hours or days.
- Critically ill patients exhibit severe AKI in over 60% of cases with mortality rates reaching 70-80%.
- Classification of AKI includes prerenal, renal, and postrenal causes.
Age and Susceptibility
- Older adults are more vulnerable to AKI due to a natural decline in functional nephrons and concurrent organ system impairments.
- Aging kidneys are less capable of handling changes in fluid volume and cardiac output.
Classification of AKI Causes
- Prerenal AKI leads to inadequate renal perfusion; patients often experience lower morbidity and mortality.
- Nonoliguric patients may develop a postoliguric phase, gradually returning urine output to normal while serum creatinine levels may remain elevated temporarily.
Diagnostic Approaches
- Diagnostic evaluations include clinical assessments, medication reviews, and laboratory tests such as CBC, BUN, serum creatinine, and urinalysis.
- Imaging studies like renal ultrasound may be used for suspected postrenal causes.
Laboratory Results in AKI
- Common findings include acidosis, hyperkalemia, hyponatremia, anemia, hyperphosphatemia, and hypocalcemia.
Management and Treatment
- Immediate focus involves identifying and reversing treatable causes like volume depletion or obstruction.
- Prerenal AKI management may include volume infusion in cases of hypovolemia, while obstructive causes require resolution of the underlying obstruction.
- Initial observations may indicate weight gain and edemas, with symptoms of uremia such as anorexia, nausea, weakness, and confusion developing later.
Phases of Urine Output in AKI
- The prodromal phase usually has normal urine output of variable duration based on underlying factors.
- The oliguric phase is characterized by urine output between 50-500 mL/day; its duration is highly variable, contingent on the AKI's cause and treatment timeline.
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Description
Test your knowledge of kidney function, fluid and electrolyte balance, and kidney diseases. This quiz covers key concepts in renal physiology and pathology.