Anatomy LE 3: CVS Histology

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What is the main function of endothelium in blood vessels?

To provide mechanical support to the vascular wall

To regulate blood pressure

To act as a semipermeable membrane between blood plasma and interstitial tissue fluid (correct)

To synthesize collagen and proteoglycans for basement membrane maintenance

What type of fibers are found in the subendothelial layer?

Muscle fibers

Elastic fibers

Nerve fibers

Collagen fibers (correct)

What is the function of ground substance in the vascular wall?

To provide mechanical support to the vascular wall

To regulate blood pressure

To affect permeability and diffusion of substances (correct)

To synthesize collagen and proteoglycans

What is the role of endothelial cells in inflammation?

To induce trans-endothelial migration of white blood cells Signup and view all the answers

What are the three main classifications of blood vessels?

Arteries, veins, and capillaries Signup and view all the answers

What is the function of Weibel-Palade bodies in endothelial cells?

To induce trans-endothelial migration of white blood cells Signup and view all the answers

What is the primary function of arteries?

To bring blood away from the heart Signup and view all the answers

What is the main component of ground substance in arterial tissues?

Glycosaminoglycans Signup and view all the answers

What is a characteristic of veins?

They have thinner walls than arteries Signup and view all the answers

What is the function of elastic material in the vascular wall?

To provide resiliency to the vascular wall Signup and view all the answers

What is the characteristic of the endothelial cell surface?

Non-thrombogenic Signup and view all the answers

What is a characteristic of arterial walls?

They are thicker and less flexible Signup and view all the answers

What is the function of internal elastic lamina in arteries?

To provide elasticity to the artery wall Signup and view all the answers

What is a function of endothelial cells in arteries?

To minimize pathological thrombus formation Signup and view all the answers

What is a characteristic of histological sections of arteries?

They are usually round and contain no blood in the lumen Signup and view all the answers

What is a function of endothelial cells in veins?

To synthesize and secrete molecules that promote thrombus formation Signup and view all the answers

What is the location of Purkinje fibers in the heart?

In the sub-endocardium Signup and view all the answers

What is the main difference between Purkinje fibers and cardiac muscles?

Purkinje fibers have fewer myofibrils Signup and view all the answers

What is the function of the fibrous rings in the heart?

To attach to the valves Signup and view all the answers

What is the composition of the central core of the heart valves?

Dense fibrous connective tissue Signup and view all the answers

What is the purpose of the endothelium in the heart valves?

To line the valves Signup and view all the answers

What is the function of the heart valves?

To prevent backflow of blood Signup and view all the answers

What is the relationship between the collagenous layer of the valve and the endocardium?

They are continuous Signup and view all the answers

What is the significance of the ECM in the heart?

It provides a structural framework for cell movement Signup and view all the answers

What type of fibers are found in the tunica adventitia?

Type I collagen Signup and view all the answers

What is the main function of vasa vasorum?

To supply nutrients to the tunica media and tunica adventitia Signup and view all the answers

What is the composition of the external elastic lamina (EEL)?

Perforated elastic lamina Signup and view all the answers

What is the arrangement of smooth muscle cells in the tunica media?

Helically arranged Signup and view all the answers

What is the outermost layer of the artery wall?

Tunica adventitia Signup and view all the answers

What is the purpose of vasa vasorum in large vessels?

To supply nutrients and oxygen to the tunica media and tunica adventitia Signup and view all the answers

What is the characteristic of the tunica media in larger arteries?

Thicker layer Signup and view all the answers

What is the importance of cell proximity to blood vessels?

To facilitate oxygen diffusion into cells Signup and view all the answers

What allows for easy entry of interstitial fluid into lymphatic capillaries?

Intercellular clefts Signup and view all the answers

What is the location where the lymphatic capillary empties its content?

Junction of the left internal jugular and left subclavian veins Signup and view all the answers