PSIO441 Unit 2 Study Guide: Chapters 13-14
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Questions and Answers

What does Functional Residual Capacity (FRC) refer to in lung mechanics?

  • The difference between inspiratory capacity and tidal volume
  • The total volume of air that can be inhaled after a normal expiration
  • The amount of air remaining in the lungs after a full expiration (correct)
  • The volume of air in the lungs at the end of inspiration

In terms of lung compliance and elasticity, which statement accurately describes their roles?

  • High elasticity correlates with high compliance, allowing for easier lung expansion
  • Compliance increases with a decrease in elastic recoil, facilitating easier breathing (correct)
  • Lung elasticity hinders compliance, making it harder to draw in air
  • Elasticity is responsible for lung expansion, while compliance aids in recoil

What does the transpulmonary pressure gradient indicate in the respiratory system?

  • The total pressure exerted by the lungs on the thoracic wall
  • The pressure difference between the alveoli and pleural space (correct)
  • The pressure required for forced expiration
  • The difference in pressure between atmospheric and intrapulmonary pressure

How do dynamic and static lung mechanics differ in measurement?

<p>Dynamic mechanics measure airflow during breathing, while static focuses on lung volume at rest (B)</p> Signup and view all the answers

Which physiological changes occur during forced expiration?

<p>Engagement of abdominal muscles and internal intercostals for pressure increase (C)</p> Signup and view all the answers

What does Functional Residual Capacity (FRC) primarily represent in the respiratory system?

<p>The volume of air that remains in the lungs after passive expiration (C)</p> Signup and view all the answers

Which statement accurately distinguishes Inspiratory Capacity (IC) from other lung volumes?

<p>It includes both the tidal volume and inspiratory reserve volume. (B)</p> Signup and view all the answers

In terms of lung mechanics, how does compliance differ from elasticity?

<p>Compliance refers to the ability to expand, while elasticity relates to the lungs' ability to recoil. (C)</p> Signup and view all the answers

What is the transpulmonary pressure gradient essential for in the lungs?

<p>Allowing for passive lung expansion and contraction (D)</p> Signup and view all the answers

Dynamic lung mechanics can best be characterized by which of the following?

<p>The interaction between airflow patterns and alveolar pressures (D)</p> Signup and view all the answers

Which factor primarily influences the Functional Residual Capacity (FRC) in healthy lungs?

<p>The elasticity of lung tissue and thoracic wall compliance (B)</p> Signup and view all the answers

What role does the intrapleural pressure (IPP) play in the respiratory mechanics?

<p>It ensures optimal expansion of the lungs during inspiration. (B)</p> Signup and view all the answers

During which condition would lung compliance be most likely to decrease?

<p>Age-related degeneration of elastic fibers (C)</p> Signup and view all the answers

What force do the muscles of the chest wall primarily overcome during inspiration?

<p>Elastic recoil of the pulmonary system (C)</p> Signup and view all the answers

What occurs when there is a deficiency in pulmonary surfactant?

<p>Increased surface tension in the alveoli (B)</p> Signup and view all the answers

In patients with Adult Respiratory Distress Syndrome (ARDS), which underlying issue is commonly present?

<p>Airway gastric aspirations (A)</p> Signup and view all the answers

What happens to the lungs at functional residual capacity (FRC)?

<p>Muscles are relaxed with a tendency to collapse (A)</p> Signup and view all the answers

Which of the following correctly describes lung compliance?

<p>It indicates the ability of lungs to expand with pressure changes (D)</p> Signup and view all the answers

Which forces must be overcome during the active process of inspiration?

<p>Inertia associated with flowing air and moving tissues, tissue, and flow resistance (D)</p> Signup and view all the answers

How does pulmonary surfactant affect alveoli during respiration?

<p>It prevents collapse of alveoli by reducing surface tension (A)</p> Signup and view all the answers

What is the relationship between transpulmonary pressure and lung volume during inspiration?

<p>Transpulmonary pressure increases, leading to lung volume expansion (B)</p> Signup and view all the answers

What defines the difference between dynamic and static lung mechanics?

<p>Static mechanics evaluate lung function at rest or non-airflow conditions (B)</p> Signup and view all the answers

Which statement accurately describes Functional Residual Capacity (FRC)?

<p>FRC is the amount of air remaining in the lungs after a forced exhalation. (A), FRC can be diminished by conditions that restrict lung expansion. (B)</p> Signup and view all the answers

How does Inspiratory Capacity (IC) relate to lung volumes?

<p>IC is the maximum volume of air that can be inspired after a normal expiration. (C)</p> Signup and view all the answers

What is the primary difference between lung compliance and lung elasticity?

<p>Compliance refers to lung expansion while elasticity refers to lung recoil. (D)</p> Signup and view all the answers

What does the transpulmonary pressure gradient indicate?

<p>The pressure difference between the alveolar space and the pleural pressure. (B)</p> Signup and view all the answers

In the context of dynamic lung mechanics, which factor most significantly affects airflow?

<p>Resistance in the airways and the compliance of lung tissues. (D)</p> Signup and view all the answers

Which condition is most likely to reduce lung compliance?

<p>Pulmonary fibrosis due to thickening of lung tissue. (A)</p> Signup and view all the answers

How do dynamic lung mechanics vary from static lung mechanics?

<p>Static measurements reflect how the lungs operate under normal resting conditions. (C), Static mechanics are important for understanding compliance only, while dynamic includes airflow rates. (D)</p> Signup and view all the answers

Which of the following is a primary function of the mucociliary escalator?

<p>To transport mucus and trapped particles out of the respiratory system. (D)</p> Signup and view all the answers

What is the importance of the high surface area in alveoli?

<p>It facilitates increased gas exchange between alveoli and pulmonary capillaries. (B)</p> Signup and view all the answers

In patients with reduced lung elasticity, which of the following is most likely to occur?

<p>Reduced efficiency of gas exchange in the alveoli. (B)</p> Signup and view all the answers

What occurs at the Functional Residual Capacity (FRC)?

<p>The outward recoil of the chest wall is counterbalanced by the inward recoil of the lungs. (A)</p> Signup and view all the answers

What is indicated when the transpulmonary pressure gradient is negative?

<p>The lungs are in a state of collapse. (B)</p> Signup and view all the answers

How is lung compliance defined?

<p>The effort required to stretch or distend the lungs during inspiration. (C)</p> Signup and view all the answers

What is the primary function of surfactant in the context of lung mechanics?

<p>To reduce the surface tension in alveoli, preventing collapse. (B)</p> Signup and view all the answers

When does air leave the lungs in relation to atmospheric pressure?

<p>When the intra-alveolar pressure is greater than atmospheric pressure. (C)</p> Signup and view all the answers

What relationship does high compliance have with lung function?

<p>It reflects a low effort required for lung inflation. (A)</p> Signup and view all the answers

What occurs when the lung tissue exhibits low elasticity?

<p>The lungs are difficult to deflate after inflation. (D)</p> Signup and view all the answers

Which factor primarily influences the development of a negative intrapleural pressure (IPP)?

<p>The outward recoil of the chest wall. (A)</p> Signup and view all the answers

In static lung mechanics, what is the primary consideration?

<p>The volumes and pressures measured without airflow. (A)</p> Signup and view all the answers

What role does the elastic recoil of the lung tissue play in breathing?

<p>It drives the movement of air out during expiration. (C)</p> Signup and view all the answers

Flashcards

Visceral Pleura

The membrane that directly covers the lungs.

Parietal Pleura

The membrane that lines the inner surface of the chest wall.

Intrapleural Pressure

Pressure inside the pleural sac, usually less than atmospheric pressure.

Tidal Volume

The volume of air inhaled or exhaled in a single breath.

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Functional Residual Capacity (FRC)

Amount of gas remaining in the lungs after a passive exhalation.

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Inspiratory Capacity (IC)

Maximal volume of air that can be inhaled from the end of a passive exhalation.

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Static Respiratory Mechanics

The forces involved in maintaining lung volume at equilibrium.

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Isolated Recoil Forces

Elastic forces of lungs and chest wall that oppose and interact to determine lung volume at rest.

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Elastic Recoil of Lungs

The tendency of the lungs to return to their resting volume after being stretched.

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Surfactant

A substance that reduces surface tension in the alveoli, preventing lung collapse.

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Infant Respiratory Distress Syndrome (IRDS)

A condition of premature babies caused by insufficient surfactant production, leading to breathing difficulties.

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Adult Respiratory Distress Syndrome (ARDS)

A condition causing breathing problems due to impaired surfactant production, often from causes like infection or aspiration

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Functional Residual Capacity (FRC)

The lung volume at the end of a normal passive exhalation where the tendency of the lung to collapse is balanced by the tendency of the chest wall to expand.

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Inspiration

The active process of breathing air into the lungs.

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Elastic Recoil Forces Inspiration

The force exerted by the lungs and chest wall opposing expansion.

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Tissue Resistance (Inspiration)

Friction between lung tissues when they slide against each other during chest wall movement.

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Flow Resistance (Inspiration)

Friction between air and airway surfaces during ventilation.

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Inertia (Inspiration)

The resistance to change in the motion of lung tissue.

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Lung Recoil

Inward force of the lungs, trying to collapse them; driven by elastic properties of lung tissue and alveoli

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Chest Wall Recoil

Outward force of the chest wall; wants to expand

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FRC (Functional Residual Capacity)

Lung volume where outward chest wall recoil balances inward lung recoil

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Intrapleural Pressure (IPP)

Pressure in the fluid-filled space between lungs and chest wall; usually sub-atmospheric (negative)

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Transpulmonary Pressure Gradient

Difference in pressure between inside and outside of the lung; keeps lungs inflated

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Positive Transpulmonary Pressure (PTM)

PTM > 0 Lungs are inflated

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Compliance

Ability of the lungs to stretch and expand during inspiration (breathing in)

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Elasticity

Ability of the lungs to return to their normal shape during expiration (breathing out)

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Elastic Recoil Components

Two parts: Lung tissue elasticity and Chest wall elasticity. The lung tissue contributes more.

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Surfactant's Role in Recoil

Reduces surface tension in the alveoli, preventing lung collapse, essential for good elasticity.

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Conducting Zone

Part of the lungs that carries air but doesn't exchange gases.

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Respiratory Zone

Part of the lungs where gas exchange occurs.

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Alveoli

Tiny air sacs in the lungs where gas exchange happens.

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Mucociliary Escalator

Mechanism that moves mucus out of the lungs.

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Type 1 Alveolar Cells

Flattened cells in alveoli walls that facilitate gas exchange.

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Type 2 Alveolar Cells

Produce surfactant, preventing alveolar collapse.

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Bronchioles

Small air passages in the lungs, regulate airflow.

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Pulmonary Surfactant

Chemical that reduces surface tension in alveoli.

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Lung Lobes

Sections of the lungs.

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Thoracic Wall

The skeletal structure surrounding the lungs.

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Inspiration Mechanism

The active process of drawing air into the lungs.

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Expiration Mechanism

The passive or active process of expelling air out of the lungs.

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Forced Expiration

Active expulsion of air from the lungs beyond normal expiration.

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Parasympathetic Stimulation(Airways)

Causes bronchoconstriction or increased airway resistance, and mucus production.

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Sympathetic Stimulation(Airways)

Causes bronchodilation; Widening airways

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Study Notes

PSIO441 - Unit 2 Study Guide

  • Exam covers chapters 13 and 14.
  • Use PowerPoint slides, notes, textbook, and online resources for study.
  • Study guide is a comprehensive review, but not all topics will be on the exam.
  • Exam: 50 multiple choice, true/false, and sequential order questions.
  • 23 questions about respiratory, 27 questions about renal.
  • Review sessions are available on Sunday night, 5-6 PM, in lecture hall.

Chapter 13 - Respiratory

  • Respiration: Sum of processes accomplishing passive O2 movement from atmosphere to tissues and passive CO2 movement from tissues to atmosphere. This supports cell metabolism.

  • Cellular Respiration: Intracellular processes in mitochondria using O2 and producing CO2 to release energy from nutrients.

  • External Respiration: Complete sequence of O2 and CO2 exchange between environment and cells.

  • Relationship between PO2 and Hb Saturation: Direct proportional relationship

    • As PO2 increases, Hb saturation increases.
  • Four steps of external respiration:

  • 1. Ventilation: Movement of air into and out of lungs.

  • 2. Diffusion: O2 and CO2 exchange between air in alveoli and blood in pulmonary capillaries.

  • 3. Blood Transport: O2 and CO2 movement between lungs and tissues.

  • 4. Diffusion: O2 and CO2 exchange between tissues and blood in systemic capillaries.

  • Lung vs. Airways: Understand the difference between lung tissues and the airways.

    • Lungs: Occupy the thoracic cavity, have lobes and segmented structures, composed of airways, alveoli, blood vessels, elastic connective tissue, outer chest wall (ribs, muscles).
  • Lung Anatomy: Conducting Zone vs. Respiratory Zone

  • Conducting Zone: End of the airways, no gas exchange, composed of trachea, bronchi, and bronchioles.

  • Respiratory Zone: Gas exchange occurs, includes respiratory bronchioles and alveolar sacs.

  • Alveoli: Air sacs for gas exchange. Surrounded by capillaries. Type 1 cells form walls, and Type 2 cells secrete surfactant.

Additional Notes

  • High surface area for capillary exchange: Increased diffusion capacity.
  • Mucociliary Escalator: Mucus movement in conductive zone to push out foreign material.
  • Alveoli and Capillaries: Capillaries surrounding alveoli facilitate gas exchange; close proximity is crucial.
  • Pleural Space: Between visceral pleura (lining lungs) and parietal pleura (lining chest wall). Contains pleural fluid.
  • Ventilation Pressures: Atmospheric, intra-alveolar, and intrapleural pressures influence ventilation.
  • Spirometry: Tracing and lung volumes/capacities (TV, IRV, ERV, RV, VC, TLC, FRC, IC).
  • Static Respiratory Mechanics: Forces influencing lung inflation/deflation (lung recoil, chest wall recoil, and surface tension).
  • Dynamic Respiratory Mechanics: Forces in inspiration and expiration (elastic recoil, friction, inertia).
  • Compliance: Effort needed to stretch or distend the lungs.
  • Elasticity: Tendency of the lungs to return to their initial volume after stretching.
  • Surfactant: Decrease surface tension to prevent alveolar collapse.
  • Abnormal Breathing Patterns: Hyperventilation (increased CO2 removal) vs. Hypoventilation (decreased CO2 removal).
  • Alveolar Ventilation: Process of exchanging O2 and CO2 between alveoli and environment (involves gradients).
  • Oxygen-Hemoglobin Dissociation Curve: Relationship between Po2 and Hb saturation changes with pH, temperature, pCO2, and 2,3 BPG. A rightward shift indicates reduced Hb affinity for O2; left shift indicates enhanced affinity.

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Prepare for the PSIO441 exam with this comprehensive study guide covering chapters 13 and 14. Focused on respiratory and renal topics, this guide includes key concepts such as respiration and cellular respiration. Utilize your PowerPoint slides, notes, and textbook for a well-rounded review.

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