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Questions and Answers
What age group is most commonly affected by central giant cell tumors?
What age group is most commonly affected by central giant cell tumors?
Which of the following locations is most commonly associated with central giant cell tumors?
Which of the following locations is most commonly associated with central giant cell tumors?
What is a notable radiographic feature of central giant cell tumors?
What is a notable radiographic feature of central giant cell tumors?
What histological feature is commonly seen in central giant cell tumors?
What histological feature is commonly seen in central giant cell tumors?
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In what population is the lingual mandibular salivary gland depression most prevalent?
In what population is the lingual mandibular salivary gland depression most prevalent?
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Which characteristic distinguishes a pseudo-cyst from a true cyst?
Which characteristic distinguishes a pseudo-cyst from a true cyst?
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At what age is a pseudo-cyst most commonly discovered?
At what age is a pseudo-cyst most commonly discovered?
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Which of the following is a common radiographic feature of a pseudo-cyst?
Which of the following is a common radiographic feature of a pseudo-cyst?
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What is the primary etiology proposed for the formation of a pseudo-cyst?
What is the primary etiology proposed for the formation of a pseudo-cyst?
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Which histopathological feature might occasionally be found in the wall of a pseudo-cyst?
Which histopathological feature might occasionally be found in the wall of a pseudo-cyst?
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Which location is most commonly associated with pseudo-cysts?
Which location is most commonly associated with pseudo-cysts?
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How do pseudo-cysts usually manifest in patients?
How do pseudo-cysts usually manifest in patients?
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What type of tissue primarily constitutes the wall of a pseudo-cyst?
What type of tissue primarily constitutes the wall of a pseudo-cyst?
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Study Notes
Pseudo Cyst Overview
- Pseudo cysts are pathologic spaces, not lined by epithelium.
- They are filled with fluid or semi-solid material.
- They are unlike true cysts, which have a clearly defined epithelial cell layer.
Pseudo Cyst Types
- Classification: Pseudo cysts can be further classified as Traumatic or Developmental.
- Traumatic Pseudo Cysts: Can be Aneurysmal, or Traumatic in nature.
- Developmental Pseudo Cysts: Are associated with static bone cyst and bone marrow defects
- Etiology and Pathogenesis (Traumatic): Result from injury and hemorrhage within the bone. Failure of clot organization and repair leads to pseudo cyst formation.
Pseudo Cyst Clinial Characteristics
- Age: Typically between 10 and 20 years old.
- Location: Primarily in the mandible, often in the premolar-molar region.
- Sex: More frequent in females.
- Manifestations: Usually asymptomatic, discovered accidentally. Often associated with vital teeth. May appear as an empty cavity upon surgical inspection.
Radiographic Features
- Appearance: Well-defined radiolucent area without noticeable sclerotic rim. Projections have a scalloped upward appearance between the roots of teeth.
- Root Resorption: No root resorption of related teeth is expected.
Histopathological Features
- Structure: Empty spaces of varying sizes. Rough, bony walls. Can sometimes contain small amounts of fluid.
- Surrounding Tissue: Surrounded by thin bands of vascular, fibrous connective tissue. Occasionally, multinucleated giant cells may be present.
Aneurysmal Bone Cyst
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Etiology and Pathogenesis: Most likely a reactive lesion to vascular malformation (arteriovenous shunt) rather than a cystic process.
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Secondary Development: Can develop secondary to disrupted blood flow in a pre-existing bone lesion, such as a central giant cell tumor.
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Clinical Features: Observed in patients between 10-20 years. Commonly found in the shafts of long bones and less often near the jaw, especially the posterior mandibular area. The condition appears as rapidly growing swelling. Frequently is accompanied by pain or paresthesia.
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Imaging (radiographically): Multilocular radiolucencies exhibiting cortical thinning and bone expansion. A "soap bubble" appearance.
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Microscopically: Spaces of varying sizes filled with unclotted blood. Surrounded by cellular fibroblastic tissue. The wall contains multinucleated giant cells and osteoid tissue.
Static Bone Cyst (Stafne's Defect)
- Definition: Developmental focal concavity in the lingual cortex of the mandible (usually around the third molar area), typically below the inferior alveolar canal.
- Etiology and Pathogenesis: Entrapment of submandibular salivary gland tissue during jaw development.
- Clinical Features: Primarily found in adults (80-90% of cases are in adults). Posterior defects are located where submandibular glands are attached. Lesion size remains stable over time
- Radiographic: Well-defined, unilocular radiolucent area in the mandible. Often unilateral
- No biopsy required. CT and sialogram scans can aid diagnosis.
Mucous Extravasation Cyst
- Etiology: Result of trauma to the minor salivary gland duct.
- Mechanism: Duct rupture causing saliva to spill into the tissue instead of the oral cavity.
- Microscopic Appearance: Rounded pool of mucus. Found within fibrous connective tissue. Inflammatory cells (macrophages) are also present; they contain phagocytized mucus.
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Description
This quiz covers the essential aspects of pseudo cysts, including their definitions, classifications, and clinical characteristics. Explore the differences between traumatic and developmental pseudo cysts, along with their etiology and typical demographic presentations. Ideal for medical students and practitioners interested in pathology.
