Pancreatic Lesions and Pseudocysts
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Questions and Answers

What is the most common complication of a pancreatic pseudocyst?

  • Spontaneous rupture (correct)
  • Development of cancer
  • Infection of the cyst
  • Formation of new cysts

    • Which pancreatic condition is characterized by the breakdown of tissue forming a sterile abscess?

  • Hemorrhagic pancreatitis
  • Phlegmonous pancreatitis
  • Pancreatic pseudocyst (correct)
  • Chronic pancreatitis

    • What risk factor is NOT associated with adenocarcinoma of the pancreas?

  • High fat diet
  • Increased alcohol consumption (correct)
  • Smoking
  • Chronic pancreatitis

    • Which of the following is NOT a characteristic of endocrine pancreatic neoplasms?

    <p>Most are benign</p> Signup and view all the answers

    The Whipple procedure involves the removal of which structures?

    <p>Head of the pancreas, duodenum, and gallbladder</p> Signup and view all the answers

    Which condition is characterized by the presence of necrotic pancreatic tissue and associated liquid collections?

    <p>Pancreatic abscess</p> Signup and view all the answers

    What is the primary characteristic of hemorrhagic pancreatitis?

    <p>Blood leakage into the peritoneal cavity</p> Signup and view all the answers

    Chronic pancreatitis is most often associated with which of the following factors?

    <p>Excessive alcohol consumption</p> Signup and view all the answers

    What is a common complication developed from chronic pancreatitis?

    <p>Pancreatic neoplasms</p> Signup and view all the answers

    What distinguishes a pancreatic pseudocyst from a pancreatic abscess?

    <p>Formed by the inflammatory response</p> Signup and view all the answers

    What characterizes hemorrhagic pancreatitis?

    <p>Progression of acute pancreatitis with vessel rupture</p> Signup and view all the answers

    Which statement best describes phlegmonous pancreatitis?

    <p>Inflammation causing necrosis along fascial pathways</p> Signup and view all the answers

    What is one of the significant features of chronic pancreatitis?

    <p>Recurrent acute pancreatitis causing ongoing damage</p> Signup and view all the answers

    How does a pancreatic abscess typically present sonographically?

    <p>Poorly defined hypoechoic mass</p> Signup and view all the answers

    Which of the following is NOT a typical cause of chronic pancreatitis?

    <p>Routine pancreatic duct obstruction</p> Signup and view all the answers

    Chronic pancreatitis is associated with all of the following changes EXCEPT:

    <p>Enlargement of the pancreas</p> Signup and view all the answers

    What is the primary concern with phlegmonous pancreatitis?

    <p>Localized areas of necrosis from inflammation</p> Signup and view all the answers

    Which of the following describe pancreatic neoplasms?

    <p>They often present with abdominal pain and weight loss</p> Signup and view all the answers

    Study Notes

    Pancreatic Pseudocysts

    • Acquired condition where pancreatic enzymes leak and break down tissue, forming a sterile abscess in the abdomen.
    • Walls are not true cyst walls, giving rise to the name "pseudocyst."
    • Not always spherical as they take the shape of the surrounding space.
    • May contain internal echoes and loculations.
    • Most common complication is spontaneous rupture (5% of cases).
    • Half of ruptures drain into the peritoneal cavity, causing sudden shock and peritonitis.
    • 50% mortality rate.

    Cystic Lesions of the Pancreas (Congenital)

    • Autosomal Dominant Polycystic Kidney Disease
    • Von Hippel-Lindau Disease
    • Cystic Fibrosis
    • True Pancreatic Cysts

    Exocrine Pancreatic Lesions

    • Solid: Adenocarcinoma
    • Cystic: Cystadenoma, Cystadenocarcinoma

    Adenocarcinoma

    • Most common primary neoplasm of the pancreas.
    • Accounts for over 90% of malignant pancreatic tumors.
    • 60-70% occur in the head of the pancreas.
    • Appear hypoechoic with irregular borders sonographically.
    • Metastasizes to liver, lung, lymph nodes, and bone.
    • Can cause obstructive jaundice.

    Risk Factors for Adenocarcinoma

    • Smoking
    • High-fat diet
    • Diabetes
    • Chronic pancreatitis

    The Whipple Procedure

    • Surgical procedure that removes the C-loop of the duodenum, head of the pancreas, gallbladder, and common bile duct (CBD).
    • Seldom has a good outcome, but complete cure is possible.

    Endocrine Pancreatic Neoplasms

    • Arise from islet cells.
    • Slow growth rate.
    • Most are malignant.
    • Difficult to detect due to small size and location in the tail and body of the pancreas.
    • Appear hypoechoic and solitary.
    • Types include:
      • Insulinoma (60%)
      • Gastrinoma (18%)

    Metastatic Disease to the Pancreas

    • Rare

    Pancreatic Transplants

    • Usually performed for diabetes.
    • Sometimes done in conjunction with renal transplants.
    • Located in the right lower quadrant (RLQ) of the abdomen.
    • Rejection manifests as higher resistance flow and heterogeneous echo patterns.

    Lab Values

    • Serum Amylase: Elevated levels (2x normal) indicative of acute pancreatitis, but can be affected by other diseases.
    • Urine Amylase: May be elevated in pancreatitis.
    • Lipase: Evaluates damage to the pancreas.
    • Glucose: Useful for detecting glucose metabolism disorders.

    Scanning Techniques

    • Challenging due to surrounding stomach and bowel.
    • Appears iso- or hyperechoic compared to the liver.
    • Use 5 MHz transducer.
    • Begin in the transverse plane, rotated slightly counterclockwise.
    • Identify the splenic vein.
    • Be cautious with the long axis view, differentiating between patient position and organ orientation.

    Anatomical Landmarks

    • Superior Mesenteric Vein (SMV)
    • Gastroduodenal Artery (GDA)
    • Superior Mesenteric Artery (SMA)
    • Splenic Vein (SV)
    • Inferior Vena Cava (IVC)

    Sagittal Views

    • Pancreas (PANC)
    • Gastroduodenal Artery (GDA)
    • Hepatic Artery (HEPATIC A)
    • Portal Vein (PV)
    • Inferior Vena Cava (IVC)
    • Gallbladder (GB)

    Pancreatic Duct

    • Identify pancreatic tissue on both sides of the duct.
    • Use color Doppler to ensure it is not a blood vessel.
    • Appears transversely.
    • Normal size is 2mm or less.

    Pancreatitis

    • Pancreas is digested by its own enzymes.
    • Most common cause is biliary tract obstruction.
    • Alcohol abuse is the second most common cause.
    • Sonographically, acute pancreatitis presents as a hypoechoic, enlarged pancreas.

    Hemorrhagic Pancreatitis

    • Rapid progression of acute pancreatitis with rupture of pancreatic vessels and subsequent hemorrhage.

    Phlegmonous Pancreatitis

    • An inflammatory process that spreads along fascial pathways causing localized areas of diffuse inflammatory edema that may progress to necrosis.

    Pancreatic Abscess

    • Serious complication.
    • Secondary to pancreatitis, post-operative procedures, or neighboring infections.
    • Appears sonographically as a poorly defined hypoechoic mass.

    Chronic Pancreatitis

    • Recurrent attacks of acute pancreatitis.
    • Causes continuous destruction of pancreatic parenchyma.
    • Characterized by fibrous scarring, loss of acinar cells, and a plugged pancreatic duct.
    • Sonographically:
      • Increased echogenicity.
      • Decreased size.
      • Calcifications

    The Pancreas

    • Divided into four sections:
      • Head (includes the uncinate process)
      • Neck
      • Body
      • Tail

    Normal Location

    • Anterior to the inferior vena cava (IVC) and aorta.
    • Retroperitoneal.
    • Posterior to the gastroduodenal artery.
    • Inferior to the liver.
    • Posterior to the stomach.
    • Anterior to the splenic vein.
    • Celiac trunk typically marks the superior border.
    • Tail is surrounded by the left kidney (Lk), spleen, stomach, and splenic flexure.
    • Tail is inferomedial to the spleen.

    The Pancreas

    • Lies in a transverse plane.
    • Rotated, with the head slightly inferior to the tail.
    • Size:
      • Length (head to tail) - approximately 15 cm.
      • Head is the thickest part, measuring 2-3 cm anteroposteriorly (AP).
    • Normal pancreatic duct size: 2mm or less

    Pancreatic Ducts

    • Two ducts:
      • Duct of Wirsung: Primary duct that extends the length of the pancreas.
      • Duct of Santorini: Secondary duct that drains the upper anterior head.
    • Pancreatic divisum - occurs when these ducts fail to fuse.

    The Pancreas - Exocrine & Endocrine Functions

    • Exocrine function:
      • Acini cells release digestive enzymes:
        • Lipase: digests fats
        • Amylase: digests carbohydrates
      • Pancreatic juice contains a high concentration of sodium bicarbonate to neutralize gastric acid.
    • Endocrine function:
      • Islets of Langerhans produce hormones that are released into the bloodstream.
      • Cell types:
        • Alpha: produce glucagon (increases blood glucose levels)
        • Beta: produce insulin (lowers blood glucose levels)
        • Delta: produce somatostatin (inhibits insulin and glucagon release)

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    Description

    This quiz covers the various pancreatic lesions, focusing on pancreatic pseudocysts, congenital cystic lesions, and exocrine pancreatic lesions. Test your understanding of the characteristics, complications, and classifications of these conditions, including adenocarcinoma. Gain insights into the implications of these pancreatic abnormalities.

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