Protein Synthesis and Aminoglycosides Quiz
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Questions and Answers

What is the minimum bactericidal concentration (MBC)?

  • The amount of drug that inhibits the immune system
  • The least amount of drug to inhibit growth of bacteria
  • The least amount of drug to kill 99.99% of an organism (correct)
  • The amount of drug that is always precise

What is the main reason for antibiotic resistance in animal feed?

  • Antibiotics in animal feed (correct)
  • Lack of regulation for antibiotic use in animals
  • Natural immunity in animals
  • Overuse of oral antibiotics

What are probiotics mainly used for?

  • To increase antibiotic resistance
  • To treat bacterial infections
  • To improve microbial balance (correct)
  • To treat viral infections

Which bacteria are included in the 80-90% of eyes?

<p>Coagulase negative staphylococci, Propionibacterium acnes, Corynebacterium species (A)</p> Signup and view all the answers

What does bacteriostatic mean?

<p>Inhibits bacterial growth and works with immune system (D)</p> Signup and view all the answers

Which infectious conditions are oral antibiotics indicated for?

<p>Meibomianitis, internal hordeolum, chlamydial conjunctivitis (D)</p> Signup and view all the answers

What is the function of minimum inhibitory concentration (MIC)?

<p>To inhibit bacterial growth (D)</p> Signup and view all the answers

How are probiotics regulated?

<p>'As dietary supplements and food' (D)</p> Signup and view all the answers

Which mechanism of action is associated with sauerkraut, yogurt, pickles, kefir, and kimchi?

<p>Decreasing colonization by pathogenic organisms (B)</p> Signup and view all the answers

Which antibiotic is NOT inactivated by penicillinase and is therefore pregnancy safe?

<p>Dicloxacillin (D)</p> Signup and view all the answers

What is the main effect of penicillins on bacterial cells?

<p>Blocking the PEP side chain cross-linking in peptidoglycan synthesis (B)</p> Signup and view all the answers

Which type of infection is topical antibiotics indicated for?

<p>Corneal ulcer (C)</p> Signup and view all the answers

What is the function of oral contraceptives while a person is on oral antibiotics?

<p>Reduced activity due to increased liver p450 enzyme induction (C)</p> Signup and view all the answers

Which antibiotic class has bactericidal activity against both Gram-positive and Gram-negative bacteria?

<p>Penicillins (C)</p> Signup and view all the answers

What is the effect of fermented foods like sauerkraut on gut epithelial cells?

<p>Enhancing mucin production from gut epithelial cells (D)</p> Signup and view all the answers

Which antibiotic is resistant to penicillinase and good against Gram-negative bacteria?

<p>Amoxicillin and clavulanate (Augmentin) (C)</p> Signup and view all the answers

Which class of antibiotics interferes with protein synthesis by binding to the 30S subunit, allowing misreading of mRNA, causing mutation, and premature chain termination?

<p>Aminoglycosides (D)</p> Signup and view all the answers

Which antibiotic is useful against Pseudomonas and is similar to gentamicin but more sensitive to some resistant pseudomonas strains and Pseudomonas aeruginosa?

<p>Tobramycin (C)</p> Signup and view all the answers

Which antibiotic is used in combination with dexamethasone as TobraDex and has less adverse drug reactions?

<p>Tobramycin (D)</p> Signup and view all the answers

Which antibiotic is reported to have corneal and conjunctival toxicity, as well as allergic reactions as adverse drug reactions?

<p>Gentamicin (A)</p> Signup and view all the answers

Which class of antibiotics is effective against both gram-positive and gram-negative bacteria, as well as chlamydia, and is related to anti-collagenolytic activity?

<p>Tetracyclines (D)</p> Signup and view all the answers

Which antibiotic is not used ophthalmically, administered through injection, and used in traumatic endophthalmitis and bacterial keratitis?

<p>Amikacin (C)</p> Signup and view all the answers

Which antibiotic is ineffective against Pseudomonas aeruginosa, used in combination, and reported to cause drug sensitization such as contact dermatitis?

<p>Neomycin (B)</p> Signup and view all the answers

Which antibiotic is useful against streptococcus, ineffective against pseudomonas, and has adverse drug reactions related to corneal and conjunctival toxicity?

<p>Gentamicin (A)</p> Signup and view all the answers

Which antibiotic is indicated for acne rosacea, chlamydia, meibomianitis, and ocular surface inflammatory disease?

<p>Doxycycline (C)</p> Signup and view all the answers

Which antibiotic is replaced by erythromycin for neonatal prophylaxis?

<p>Tetracycline (D)</p> Signup and view all the answers

Which antibiotic may take with food and is used for chlamydia, acne rosacea, meibomianitis, and ocular surface inflammatory disease?

<p>Doxycycline (A)</p> Signup and view all the answers

Which antibiotic is NOT indicated for neonatal prophylaxis and contains 30mg immediate release and 10mg delayed release?

<p>ORACEA (A)</p> Signup and view all the answers

Which antibiotic may cause vestibular toxicity and decreased cerebrospinal fluid absorption?

<p>Minocycline (C)</p> Signup and view all the answers

Which antibiotic is used in traumatic endophthalmitis and bacterial keratitis?

<p>Chloramphenicol (D)</p> Signup and view all the answers

Which antibiotic class includes erythromycin, azithromycin, and clarithromycin?

<p>Macrolides (D)</p> Signup and view all the answers

Which antibiotic has adverse drug reactions related to changes in tooth development, blood dyscrasias, and vestibular toxicity?

<p>Doxycycline (C)</p> Signup and view all the answers

Which statement about ORACEA is correct?

Signup and view all the answers

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