Podcast
Questions and Answers
Which antibiotic is legislated for use by midwives in the situation of GBS?
Which antibiotic is legislated for use by midwives in the situation of GBS?
- Ciprofloxacin
- Penicillin G (correct)
- Tetracycline
- Vancomycin
What is the significant cause of neonatal morbidity and mortality in North America?
What is the significant cause of neonatal morbidity and mortality in North America?
- Staphylococcus aureus
- Klebsiella pneumoniae
- E. coli
- Group B Streptococcus (GBS) (correct)
Which type of bacteria is GBS?
Which type of bacteria is GBS?
- Gram+ (correct)
- Fungal
- Gram-
- Anaerobic
Which antibiotic is not mentioned as a permissible treatment for GBS by midwives?
Which antibiotic is not mentioned as a permissible treatment for GBS by midwives?
Which guideline has replaced the CDC Guideline & algorithm of 2010 regarding Group B Strep Prevention?
Which guideline has replaced the CDC Guideline & algorithm of 2010 regarding Group B Strep Prevention?
Which type of infections does the text mention antibiotic treatment for?
Which type of infections does the text mention antibiotic treatment for?
What is the mechanism of action of Metronidazole (FLAGYL)?
What is the mechanism of action of Metronidazole (FLAGYL)?
What is a common side-effect of Metronidazole (FLAGYL)?
What is a common side-effect of Metronidazole (FLAGYL)?
What adverse effect can Metronidazole (FLAGYL) have on alcohol consumption?
What adverse effect can Metronidazole (FLAGYL) have on alcohol consumption?
How does Metronidazole (FLAGYL) affect free radicals in cells?
How does Metronidazole (FLAGYL) affect free radicals in cells?
What is the most correct statement about the drug interactions of Metronidazole (FLAGYL)?
What is the most correct statement about the drug interactions of Metronidazole (FLAGYL)?
How does Metronidazole (FLAGYL) affect urine color?
How does Metronidazole (FLAGYL) affect urine color?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
What is the first-line treatment for Gram+ streptococcus according to clinical guidelines?
What is the first-line treatment for Gram+ streptococcus according to clinical guidelines?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, what antibiotic is indicated for GBS IAP?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, what antibiotic is indicated for GBS IAP?
What is the primary route of excretion for penicillins?
What is the primary route of excretion for penicillins?
What is the preferred regimen for intravenous antibiotics for women positive by GBS culture screening?
What is the preferred regimen for intravenous antibiotics for women positive by GBS culture screening?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
Why is erythromycin not recommended for GBS prophylaxis?
Why is erythromycin not recommended for GBS prophylaxis?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
What is the main reason for the increased risk of UTIs in pregnant women?
What is the main reason for the increased risk of UTIs in pregnant women?
Which drug used for UTI treatment is a pro-drug that is reduced by microbial metabolism?
Which drug used for UTI treatment is a pro-drug that is reduced by microbial metabolism?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
Which antibiotic is a DNA synthesis inhibitor and useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor and useful for penicillin-allergic clients?
Which antibiotic should be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which antibiotic should be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which condition is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
Which condition is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which condition is characterized by overgrowth of genital tract organisms and is associated with various pregnancy complications?
Which condition is characterized by overgrowth of genital tract organisms and is associated with various pregnancy complications?
Which antibiotic is recommended for the treatment of BV, but has high recurrence rates?
Which antibiotic is recommended for the treatment of BV, but has high recurrence rates?
Which antibiotic is legislated for use by midwives in the situation of GBS?
Which antibiotic is legislated for use by midwives in the situation of GBS?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
What is the mechanism of action of Metronidazole (FLAGYL)?
What is the mechanism of action of Metronidazole (FLAGYL)?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
Which antibiotic is recommended for GBS prophylaxis in case of β-lactam hypersensitivities?
Which antibiotic is recommended for GBS prophylaxis in case of β-lactam hypersensitivities?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
Why is erythromycin not recommended for GBS prophylaxis?
Why is erythromycin not recommended for GBS prophylaxis?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
Why should UTIs in pregnancy be treated promptly?
Why should UTIs in pregnancy be treated promptly?
What is the primary reason for favoring Penicillin G over Ampicillin for the first-line treatment of Gram+ streptococcus?
What is the primary reason for favoring Penicillin G over Ampicillin for the first-line treatment of Gram+ streptococcus?
In which situation is Cefazolin recommended for the treatment of Gram+ streptococcus?
In which situation is Cefazolin recommended for the treatment of Gram+ streptococcus?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
When is Vancomycin indicated for GBS IAP?
When is Vancomycin indicated for GBS IAP?
What is the primary excretory route for penicillins?
What is the primary excretory route for penicillins?
Which antibiotic is a folate synthesis inhibitor to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which antibiotic is a folate synthesis inhibitor to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which condition is usually caused by overgrowth of genital tract organisms and is associated with various pregnancy complications?
Which condition is usually caused by overgrowth of genital tract organisms and is associated with various pregnancy complications?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions?
Which antibiotic is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions?
Which antibiotic is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
Which antibiotic is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
What is the primary mechanism of action of Metronidazole (FLAGYL)?
What is the primary mechanism of action of Metronidazole (FLAGYL)?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the main route of excretion for Metronidazole (FLAGYL)?
What is the main route of excretion for Metronidazole (FLAGYL)?
What is the mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the primary causative agent of neonatal morbidity and mortality in North America?
What is the primary causative agent of neonatal morbidity and mortality in North America?
Which antibiotic is legislated for use by midwives in the situation of GBS?
Which antibiotic is legislated for use by midwives in the situation of GBS?
What is the main route of excretion for Metronidazole (FLAGYL)?
What is the main route of excretion for Metronidazole (FLAGYL)?
What is the recommended antibiotic for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
What is the recommended antibiotic for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
What is the primary route of excretion for cefazolin?
What is the primary route of excretion for cefazolin?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
What is the common causative agent of UTIs in pregnancy?
What is the common causative agent of UTIs in pregnancy?
What is the primary adverse effect of clindamycin?
What is the primary adverse effect of clindamycin?
What is the preferred first-line treatment for Gram+ streptococcus according to clinical guidelines?
What is the preferred first-line treatment for Gram+ streptococcus according to clinical guidelines?
In case of penicillin allergy or intolerance, which antibiotic can be used for GBS prophylaxis?
In case of penicillin allergy or intolerance, which antibiotic can be used for GBS prophylaxis?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, which antibiotic is indicated for GBS IAP?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, which antibiotic is indicated for GBS IAP?
What is the primary route of excretion for penicillins?
What is the primary route of excretion for penicillins?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is a well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is a well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is a common side-effect of Metronidazole (FLAGYL)?
What is a common side-effect of Metronidazole (FLAGYL)?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the most correct statement about the drug interactions of Metronidazole (FLAGYL)?
What is the most correct statement about the drug interactions of Metronidazole (FLAGYL)?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a folate synthesis inhibitor to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which antibiotic is a folate synthesis inhibitor to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which condition is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
Which condition is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which antibiotic is effective for UTIs and bacterial vaginosis, with few drug interactions?
Which antibiotic is effective for UTIs and bacterial vaginosis, with few drug interactions?
Which antibiotic is legislated for use by midwives in the situation of GBS?
Which antibiotic is legislated for use by midwives in the situation of GBS?
What is the primary adverse effect of clindamycin?
What is the primary adverse effect of clindamycin?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is a common adverse effect of Metronidazole (FLAGYL)?
What is a common adverse effect of Metronidazole (FLAGYL)?
What is the primary route of excretion for Metronidazole (FLAGYL)?
What is the primary route of excretion for Metronidazole (FLAGYL)?
What is the main documented effect of Metronidazole (FLAGYL) on urine color?
What is the main documented effect of Metronidazole (FLAGYL) on urine color?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the primary adverse effect of Metronidazole (FLAGYL) experienced by 12% of individuals?
What is the primary route of excretion for cefazolin?
What is the primary route of excretion for cefazolin?
Which antibiotic is a pro-drug that is reduced by microbial metabolism into reactive intermediates that damage bacterial components?
Which antibiotic is a pro-drug that is reduced by microbial metabolism into reactive intermediates that damage bacterial components?
What is the most significant adverse effect of clindamycin?
What is the most significant adverse effect of clindamycin?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
Which antibiotic is a first-generation cephalosporin used for GBS prophylaxis in case of mild hypersensitivity to penicillins?
Which antibiotic is a first-generation cephalosporin used for GBS prophylaxis in case of mild hypersensitivity to penicillins?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
Which antibiotic is recommended for individuals with immediate, serious betalactam sensitivities?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
At what gestational age is screening for group B streptococcus disease recommended?
At what gestational age is screening for group B streptococcus disease recommended?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, which antibiotic is indicated for GBS IAP?
In the rare event of an anaphylactic penicillin allergy and GBS strain resistance, which antibiotic is indicated for GBS IAP?
Which antibiotic is primarily excreted through the renal route, with dependency on renal excretion keeping concentration relatively high in newborns?
Which antibiotic is primarily excreted through the renal route, with dependency on renal excretion keeping concentration relatively high in newborns?
What is the most significant adverse effect of Penicillin G or Ampicillin?
What is the most significant adverse effect of Penicillin G or Ampicillin?
What is the primary adverse effect of sulfamethoxazole-trimethoprim?
What is the primary adverse effect of sulfamethoxazole-trimethoprim?
Which antibiotic is to be avoided in the first trimester and after 32 weeks of pregnancy due to its adverse effects and folate synthesis inhibition?
Which antibiotic is to be avoided in the first trimester and after 32 weeks of pregnancy due to its adverse effects and folate synthesis inhibition?
What is the recommended treatment for vulvovaginal candidiasis in pregnancy?
What is the recommended treatment for vulvovaginal candidiasis in pregnancy?
Which antibiotic is effective for treating bacterial vaginosis, but has high recurrence rates?
Which antibiotic is effective for treating bacterial vaginosis, but has high recurrence rates?
What is the primary treatment for trichomoniasis, a sexually transmitted infection?
What is the primary treatment for trichomoniasis, a sexually transmitted infection?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, and is useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, and is useful for penicillin-allergic clients?
What is the primary route of excretion for cefazolin?
What is the primary route of excretion for cefazolin?
What is the main route of excretion for penicillins?
What is the main route of excretion for penicillins?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of Penicillin G or Ampicillin?
What is the most significant adverse effect of Penicillin G or Ampicillin?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the main documented effect of Metronidazole (FLAGYL) on urine color?
What is the main documented effect of Metronidazole (FLAGYL) on urine color?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the primary excretory route for clindamycin?
What is the primary excretory route for clindamycin?
What is the primary adverse effect of clindamycin?
What is the primary adverse effect of clindamycin?
What is the main reason for the increased risk of UTIs in pregnant women?
What is the main reason for the increased risk of UTIs in pregnant women?
Which antibiotic is recommended for GBS prophylaxis in case of β-lactam hypersensitivities?
Which antibiotic is recommended for GBS prophylaxis in case of β-lactam hypersensitivities?
What is the primary excretory route for penicillins?
What is the primary excretory route for penicillins?
In case of penicillin allergy or intolerance, which antibiotic can be used for GBS prophylaxis?
In case of penicillin allergy or intolerance, which antibiotic can be used for GBS prophylaxis?
What is the primary adverse effect of penicillin G or ampicillin?
What is the primary adverse effect of penicillin G or ampicillin?
Why is penicillin G favored over ampicillin according to ACOG and SOGC guidelines?
Why is penicillin G favored over ampicillin according to ACOG and SOGC guidelines?
What is the primary causative agent of neonatal sepsis and morbidity due to infection in newborns?
What is the primary causative agent of neonatal sepsis and morbidity due to infection in newborns?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
What is the mechanism of action of Metronidazole (FLAGYL)?
What is the mechanism of action of Metronidazole (FLAGYL)?
What is the most significant adverse effect of clindamycin?
What is the most significant adverse effect of clindamycin?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
What is the well-documented effect of Metronidazole (FLAGYL) when consumed concurrently with alcohol?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
What is the primary route of excretion for penicillins?
What is the primary route of excretion for penicillins?
What is the most significant adverse effect of cefazolin?
What is the most significant adverse effect of cefazolin?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
Which antibiotic is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients?
What is the main reason for the increased risk of UTIs in pregnant women?
What is the main reason for the increased risk of UTIs in pregnant women?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
Which antibiotic is recommended for the treatment of bacterial vaginosis (BV), but has high recurrence rates?
What is the primary adverse effect of sulfamethoxazole-trimethoprim?
What is the primary adverse effect of sulfamethoxazole-trimethoprim?
What is the first-line treatment for Gram+ streptococcus according to clinical guidelines?
What is the first-line treatment for Gram+ streptococcus according to clinical guidelines?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
What is the potential effect of Metronidazole (FLAGYL) on urine color?
Which antibiotic is legislated for use by midwives in the situation of GBS?
Which antibiotic is legislated for use by midwives in the situation of GBS?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
What is the recommended antibiotic for individuals with immediate, serious betalactam sensitivities?
What is the leading cause of neonatal sepsis and the leading cause of morbidity and mortality due to infection in newborns?
What is the leading cause of neonatal sepsis and the leading cause of morbidity and mortality due to infection in newborns?
What is the first-line treatment for Group B streptococcus (GBS) according to clinical guidelines?
What is the first-line treatment for Group B streptococcus (GBS) according to clinical guidelines?
What is the primary excretory route for penicillins?
What is the primary excretory route for penicillins?
Why does the current American Congress of Obstetricians and Gynecologists (ACOG) and Society of Obstetricians and Gynecologists of Canada (SOGC) clinical guidelines favor penicillin G over ampicillin?
Why does the current American Congress of Obstetricians and Gynecologists (ACOG) and Society of Obstetricians and Gynecologists of Canada (SOGC) clinical guidelines favor penicillin G over ampicillin?
What is the main route of excretion for cefazolin?
What is the main route of excretion for cefazolin?
What is the primary mechanism of action of penicillin G or ampicillin in the prevention of neonatal GBS infection?
What is the primary mechanism of action of penicillin G or ampicillin in the prevention of neonatal GBS infection?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the significant cause of neonatal morbidity and mortality in North America?
What is the primary adverse effect of penicillin G or ampicillin?
What is the primary adverse effect of penicillin G or ampicillin?
What is the primary causative agent of UTIs in pregnancy?
What is the primary causative agent of UTIs in pregnancy?
What is the main reason for favoring Penicillin G over Ampicillin for the first-line treatment of Gram-positive streptococcus?
What is the main reason for favoring Penicillin G over Ampicillin for the first-line treatment of Gram-positive streptococcus?
What is the primary causative agent of neonatal morbidity and mortality in North America?
What is the primary causative agent of neonatal morbidity and mortality in North America?
What percentage of Trimethoprim is excreted unchanged into the urine?
What percentage of Trimethoprim is excreted unchanged into the urine?
Which enzyme partially metabolizes Trimethoprim in the liver?
Which enzyme partially metabolizes Trimethoprim in the liver?
What is the primary excretory route for Ciprofloxacin?
What is the primary excretory route for Ciprofloxacin?
Which antibiotic is considered optimal for UTI treatment except when a known allergy to sulfa drugs is present?
Which antibiotic is considered optimal for UTI treatment except when a known allergy to sulfa drugs is present?
What percentage of Ciprofloxacin is excreted into the urine unchanged?
What percentage of Ciprofloxacin is excreted into the urine unchanged?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the primary mode of action of Ciprofloxacin?
What is the primary mode of action of Ciprofloxacin?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary excretory route for Trimethoprim?
What is the primary excretory route for Trimethoprim?
What is the primary cause of multidrug resistance in UTI-causing bacteria?
What is the primary cause of multidrug resistance in UTI-causing bacteria?
What is the primary metabolizing organ for Trimethoprim?
What is the primary metabolizing organ for Trimethoprim?
What is the primary metabolizing organ for Ciprofloxacin?
What is the primary metabolizing organ for Ciprofloxacin?
What is the primary route of excretion for Nitrofurantoin?
What is the primary route of excretion for Nitrofurantoin?
How does Nitrofurantoin affect bacterial DNA?
How does Nitrofurantoin affect bacterial DNA?
What is the primary mechanism of action for Sulfamethoxazole-Trimethoprim?
What is the primary mechanism of action for Sulfamethoxazole-Trimethoprim?
What is the primary excretory route for Sulfamethoxazole?
What is the primary excretory route for Sulfamethoxazole?
What is the plasma half-life of Nitrofurantoin?
What is the plasma half-life of Nitrofurantoin?
Why is Trimethoprim monotherapy discouraged in some clinical guidelines?
Why is Trimethoprim monotherapy discouraged in some clinical guidelines?
What is the goal of therapy for Nitrofurantoin?
What is the goal of therapy for Nitrofurantoin?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the potential effect of Sulfamethoxazole-Trimethoprim on tetrahydrofolic acid formation?
What is the potential effect of Sulfamethoxazole-Trimethoprim on tetrahydrofolic acid formation?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
What is the primary reason for the susceptibility of bacteria to Nitrofurantoin?
What is the primary reason for the susceptibility of bacteria to Nitrofurantoin?
What is the primary reason for the use of Nitrofurantoin up to four times per day?
What is the primary reason for the use of Nitrofurantoin up to four times per day?
What is the primary excretory route for Nitrofurantoin?
What is the primary excretory route for Nitrofurantoin?
Why does Nitrofurantoin have to be taken up to four times per day?
Why does Nitrofurantoin have to be taken up to four times per day?
What is the primary mode of action of Sulfamethoxazole-Trimethoprim?
What is the primary mode of action of Sulfamethoxazole-Trimethoprim?
What is the primary excretory route for Sulfamethoxazole?
What is the primary excretory route for Sulfamethoxazole?
Why is Trimethoprim monotherapy discouraged in some clinical guidelines?
Why is Trimethoprim monotherapy discouraged in some clinical guidelines?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary mode of action of Nitrofurantoin?
What is the primary mode of action of Nitrofurantoin?
What is the primary adverse effect of Sulfamethoxazole-Trimethoprim?
What is the primary adverse effect of Sulfamethoxazole-Trimethoprim?
What is the primary excretory route for Trimethoprim?
What is the primary excretory route for Trimethoprim?
What is the primary excretory route for Metronidazole?
What is the primary excretory route for Metronidazole?
What is the primary mode of action of Metronidazole?
What is the primary mode of action of Metronidazole?
What percentage of Trimethoprim is excreted unchanged into the urine?
What percentage of Trimethoprim is excreted unchanged into the urine?
What is the primary mode of action of Ciprofloxacin?
What is the primary mode of action of Ciprofloxacin?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the future focus for treating ESBL-producing bacteria in UTIs?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary cause of antibiotic resistance in UTI-causing bacteria?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
What is the primary metabolite of Nitrofurantoin that damages bacterial DNA?
Which enzyme partially metabolizes Trimethoprim in the liver?
Which enzyme partially metabolizes Trimethoprim in the liver?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
What is the primary mechanism through which Metronidazole (FLAGYL) affects microbes?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
Which antibiotic is not recommended for GBS prophylaxis due to widespread bacterial resistance?
What is the primary excretory route for cefazolin?
What is the primary excretory route for cefazolin?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
Which antibiotic can treat 80-90% of uncomplicated UTIs and should be avoided in the first trimester?
What is the recommended first-line treatment for Gram+ streptococcus according to clinical guidelines?
What is the recommended first-line treatment for Gram+ streptococcus according to clinical guidelines?
Which antibiotic is primarily excreted through the renal route, with dependency on renal excretion keeping concentration relatively high in newborns?
Which antibiotic is primarily excreted through the renal route, with dependency on renal excretion keeping concentration relatively high in newborns?
What is the primary causative agent of bacterial vaginosis (BV)?
What is the primary causative agent of bacterial vaginosis (BV)?
Which microbe is often present in bacterial vaginosis (BV) along with Gardnerella vaginalis?
Which microbe is often present in bacterial vaginosis (BV) along with Gardnerella vaginalis?
What is the characteristic odor of the vaginal discharge in bacterial vaginosis (BV)?
What is the characteristic odor of the vaginal discharge in bacterial vaginosis (BV)?
What is typically seen in a smear of the vaginal exudate when bacterial vaginosis (BV) is present?
What is typically seen in a smear of the vaginal exudate when bacterial vaginosis (BV) is present?
Which drug is the first-line treatment for bacterial vaginosis (BV)?
Which drug is the first-line treatment for bacterial vaginosis (BV)?
Which drug is activated by the disease organism itself and is used for the treatment of bacterial vaginosis (BV)?
Which drug is activated by the disease organism itself and is used for the treatment of bacterial vaginosis (BV)?
Which antibiotic is typically used for the treatment of bacterial vaginosis (BV) and has a lower rate of side effects compared to metronidazole?
Which antibiotic is typically used for the treatment of bacterial vaginosis (BV) and has a lower rate of side effects compared to metronidazole?
Which condition is typically caused by Trichomonas vaginalis and can be mistaken for bacterial vaginosis (BV)?
Which condition is typically caused by Trichomonas vaginalis and can be mistaken for bacterial vaginosis (BV)?
Which two microbes are typically associated with vaginitis?
Which two microbes are typically associated with vaginitis?
Which antibiotic is typically used for the treatment of vaginitis caused by Trichomonas vaginalis?
Which antibiotic is typically used for the treatment of vaginitis caused by Trichomonas vaginalis?
Which antibiotic is not recommended for the treatment of bacterial vaginosis (BV) due to a high recurrence rate?
Which antibiotic is not recommended for the treatment of bacterial vaginosis (BV) due to a high recurrence rate?
What is the primary effect of metronidazole and tinidazole on certain anaerobic bacteria and protozoans?
What is the primary effect of metronidazole and tinidazole on certain anaerobic bacteria and protozoans?
Study Notes
Antibiotics and Abnormal Vaginal Secretions in Pregnancy
- Ciprofloxacin is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients.
- Sulfamethoxazole-trimethoprim is a folate synthesis inhibitor, to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria.
- Sulfamethoxazole-trimethoprim can cause allergic reactions, Stevens-Johnson syndrome, and toxic epidermal necrolysis, and interacts with other drugs.
- Trimethoprim, which can treat 80-90% of uncomplicated UTIs, is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions.
- Abnormal vaginal secretions can be caused by bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis.
- BV, characterized by overgrowth of genital tract organisms, is associated with various pregnancy complications.
- Vulvovaginal candidiasis is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy.
- Trichomoniasis is a sexually transmitted infection treated with metronidazole, but not within the midwifery scope to treat.
- Metronidazole and clindamycin are recommended treatments for BV, but recurrence rates are high.
- Bacterial vaginosis treatment can be extended to 10-14 days for effective management of repeated recurrences.
- Pregnant women should avoid ciprofloxacin and sulfamethoxazole-trimethoprim in the first trimester and after 32 weeks.
- Trimethoprim and metronidazole are effective treatments for UTIs and bacterial vaginosis, respectively, with few drug interactions.
Antibiotics and Abnormal Vaginal Secretions in Pregnancy
- Ciprofloxacin is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients.
- Sulfamethoxazole-trimethoprim is a folate synthesis inhibitor, to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria.
- Sulfamethoxazole-trimethoprim can cause allergic reactions, Stevens-Johnson syndrome, and toxic epidermal necrolysis, and interacts with other drugs.
- Trimethoprim, which can treat 80-90% of uncomplicated UTIs, is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions.
- Abnormal vaginal secretions can be caused by bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis.
- BV, characterized by overgrowth of genital tract organisms, is associated with various pregnancy complications.
- Vulvovaginal candidiasis is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy.
- Trichomoniasis is a sexually transmitted infection treated with metronidazole, but not within the midwifery scope to treat.
- Metronidazole and clindamycin are recommended treatments for BV, but recurrence rates are high.
- Bacterial vaginosis treatment can be extended to 10-14 days for effective management of repeated recurrences.
- Pregnant women should avoid ciprofloxacin and sulfamethoxazole-trimethoprim in the first trimester and after 32 weeks.
- Trimethoprim and metronidazole are effective treatments for UTIs and bacterial vaginosis, respectively, with few drug interactions.
Antibiotics and Abnormal Vaginal Secretions in Pregnancy
- Ciprofloxacin is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients.
- Sulfamethoxazole-trimethoprim is a folate synthesis inhibitor, to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria.
- Sulfamethoxazole-trimethoprim can cause allergic reactions, Stevens-Johnson syndrome, and toxic epidermal necrolysis, and interacts with other drugs.
- Trimethoprim, which can treat 80-90% of uncomplicated UTIs, is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions.
- Abnormal vaginal secretions can be caused by bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis.
- BV, characterized by overgrowth of genital tract organisms, is associated with various pregnancy complications.
- Vulvovaginal candidiasis is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy.
- Trichomoniasis is a sexually transmitted infection treated with metronidazole, but not within the midwifery scope to treat.
- Metronidazole and clindamycin are recommended treatments for BV, but recurrence rates are high.
- Bacterial vaginosis treatment can be extended to 10-14 days for effective management of repeated recurrences.
- Pregnant women should avoid ciprofloxacin and sulfamethoxazole-trimethoprim in the first trimester and after 32 weeks.
- Trimethoprim and metronidazole are effective treatments for UTIs and bacterial vaginosis, respectively, with few drug interactions.
Antibiotics and Abnormal Vaginal Secretions in Pregnancy
- Ciprofloxacin is a DNA synthesis inhibitor, excreted in urine and feces, with a half-life of 3-5 hours, useful for penicillin-allergic clients.
- Sulfamethoxazole-trimethoprim is a folate synthesis inhibitor, to be avoided in the first trimester and after 32 weeks, and has adverse effects like hemolytic anemia and crystalluria.
- Sulfamethoxazole-trimethoprim can cause allergic reactions, Stevens-Johnson syndrome, and toxic epidermal necrolysis, and interacts with other drugs.
- Trimethoprim, which can treat 80-90% of uncomplicated UTIs, is a folate synthesis inhibitor to avoid in the first trimester, and has few drug interactions.
- Abnormal vaginal secretions can be caused by bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis.
- BV, characterized by overgrowth of genital tract organisms, is associated with various pregnancy complications.
- Vulvovaginal candidiasis is usually caused by Candida albicans and can be treated with OTC treatments in pregnancy.
- Trichomoniasis is a sexually transmitted infection treated with metronidazole, but not within the midwifery scope to treat.
- Metronidazole and clindamycin are recommended treatments for BV, but recurrence rates are high.
- Bacterial vaginosis treatment can be extended to 10-14 days for effective management of repeated recurrences.
- Pregnant women should avoid ciprofloxacin and sulfamethoxazole-trimethoprim in the first trimester and after 32 weeks.
- Trimethoprim and metronidazole are effective treatments for UTIs and bacterial vaginosis, respectively, with few drug interactions.
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Test your knowledge of antibiotics and abnormal vaginal secretions in pregnancy with this quiz. Explore the use of antibiotics like ciprofloxacin, sulfamethoxazole-trimethoprim, and trimethoprim in pregnancy, and learn about their potential effects and interactions. Delve into the causes and treatments of abnormal vaginal secretions, including bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis.