Antibiotics: focused on contraindicated in pregnancy/alternatives for pcn allergies/MOA
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Questions and Answers

Which division of antibiotics directly kills bacteria?

  • Both bactericidals and bacteriostatics
  • Antibiotics do not directly kill bacteria
  • Bacteriostatics
  • Bactericidals (correct)

    • What is the effect of antibiotics on the health of people?

  • No effect
  • Profound effect (correct)
  • Moderate effect
  • Minimal effect

    • Which antibiotics cover methicillin-resistant Staphylococcus aureus (MRSA)?

  • Vancomycin
  • Ceftobiprole
  • Doxycycline
  • All of the above (correct)

    • Which class of antibiotics is usually effective against vancomycin-resistant Enterococcus (VRE)?

    <p>Tetracyclines</p> Signup and view all the answers

    Which of the following antibiotics is NOT effective against vancomycin-resistant Enterococcus (VRE)?

    <p>Ciprofloxacin</p> Signup and view all the answers

    Which generation of cephalosporins is Ceftobiprole?

    <p>5th generation</p> Signup and view all the answers

    True or false: Ceftazidime is a 4th generation cephalosporin?

    <p>False</p> Signup and view all the answers

    True or false: Vancomycin is effective against vancomycin-resistant Enterococcus (VRE)?

    <p>False</p> Signup and view all the answers

    True or false: Daptomycin is an advanced generation tetracycline?

    <p>False</p> Signup and view all the answers

    True or false: Bactericidal antibiotics prevent bacteria from dividing.

    <p>False</p> Signup and view all the answers

    True or false: Both people and animals have used antibiotics to treat infections and diseases.

    <p>True</p> Signup and view all the answers

    True or false: Tigecycline is an antibiotic that covers Pseudomonas aeruginosa.

    <p>True</p> Signup and view all the answers

    Which class of antibiotics is contraindicated for pregnancy?

    <p>Tetracyclines</p> Signup and view all the answers

    Which of the following drugs is contraindicated for pregnancy and used for the treatment of fungal infections?

    <p>Griseofulvin</p> Signup and view all the answers

    True or false: Gentamicin is contraindicated for pregnancy?

    <p>True</p> Signup and view all the answers

    True or false: Trimethoprim-sulfamethoxazole is safe to use during pregnancy?

    <p>False</p> Signup and view all the answers

    True or false: Fluconazole is contraindicated for pregnancy?

    <p>True</p> Signup and view all the answers

    Which of the following drugs is contraindicated for pregnancy and inhibits cell protein synthesis?

    <p>Doxycycline</p> Signup and view all the answers

    Which of the following drugs is NOT contraindicated for pregnancy and can be used in a patient with a history of severe penicillin allergy?

    <p>Vancomycin</p> Signup and view all the answers

    Which of the following drugs is contraindicated for pregnancy and does NOT inhibit cell protein synthesis?

    <p>Fluconazole</p> Signup and view all the answers

    True or false: Isotretinoin is contraindicated for pregnancy?

    <p>True</p> Signup and view all the answers

    True or false: Tetracyclines inhibit cell protein synthesis?

    <p>True</p> Signup and view all the answers

    True or false: Aztreonam can be used in a patient with a history of severe penicillin allergy?

    <p>True</p> Signup and view all the answers

    The following drugs are ______ for pregnancy: Category D or X Gentamicin, Neomycin, Amikacin, Streptomycin, Kanamycin Trimethoprim-sulfamethoxazole Doxycycline, Minocycline, Tetracycline, Tigecycline Fluconazole, Voriconazole, Griseofulvin, Isotretinoin

    <p>contraindicated</p> Signup and view all the answers

    The following drugs ______ cell protein synthesis: Macrolides Aminoglycocides Lincosamides Tetracyclines

    <p>inhibit</p> Signup and view all the answers

    Match the following drugs with their contraindication status for pregnancy:

    <p>Gentamicin = Contraindicated Neomycin = Contraindicated Trimethoprim-sulfamethoxazole = Contraindicated Isotretinoin = Contraindicated</p> Signup and view all the answers

    Match the following drug classes with their action on cell protein synthesis:

    <p>Macrolides = Inhibit protein synthesis Aminoglycocides = Inhibit protein synthesis Lincosamides = Inhibit protein synthesis Tetracyclines = Inhibit protein synthesis</p> Signup and view all the answers

    Match the following drugs with their suitability for a patient with a history of severe penicillin allergy:

    <p>Monobactam (aztreonam) = Suitable Vancomycin = Suitable Doxycycline = Suitable Ciprofloxacin = Suitable</p> Signup and view all the answers

    Study Notes

    Antibiotics and Bacterial Action

    • Bactericidal antibiotics directly kill bacteria instead of merely inhibiting their growth.
    • Antibiotics can disrupt the normal flora, potentially leading to antibiotic resistance and secondary infections.

    MRSA and VRE Coverage

    • Effective antibiotics for methicillin-resistant Staphylococcus aureus (MRSA) include vancomycin, linezolid, and daptomycin.
    • Linezolid is usually effective against vancomycin-resistant Enterococcus (VRE).

    Cephalosporins and Generations

    • Ceftobiprole belongs to the 5th generation of cephalosporins.
    • Ceftazidime is classified as a 3rd generation cephalosporin.

    Effectiveness Against VRE

    • Vancomycin is not effective against vancomycin-resistant Enterococcus (VRE).
    • Daptomycin is not a tetracycline; it's a lipopeptide antibiotic used for resistant infections.

    Antibiotic Characteristics

    • Bactericidal antibiotics kill bacteria, while bacteriostatic antibiotics impede their division.
    • Both humans and animals have historically used antibiotics to treat infections.

    Pregnancy Considerations

    • Tetracyclines are contraindicated during pregnancy due to potential harm to fetal development.
    • Fluconazole is also contraindicated during pregnancy.

    Contraindicated Drugs in Pregnancy

    • Gentamicin and the aminoglycosides are not recommended for pregnant individuals.
    • Trimethoprim-sulfamethoxazole is not safe for use during pregnancy.
    • Aztreonam is generally considered safe for patients with a history of severe penicillin allergy.

    Drug Categories and Protein Synthesis

    • Certain antibiotics that inhibit cell protein synthesis include macrolides, aminoglycosides, lincosamides, and tetracyclines.
    • Isotretinoin is contraindicated during pregnancy due to teratogenic effects.

    Summary of Drug Classes

    • Drugs categorized as Category D or X include aminoglycosides (Gentamicin, Neomycin), Trimethoprim-sulfamethoxazole, and Tetracyclines (Doxycycline, Minocycline).
    • Fluconazole, voriconazole, and isotretinoin are also included in the contraindicated list for pregnancy.

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    Description

    Test your knowledge on antibiotics and their classifications! Learn about the differences between bactericidal and bacteriostatic antibiotics and how they impact bacteria. Discover the profound impact antibiotics have on human and animal health.

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