Polysomnography and Sleep Stages
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Questions and Answers

What defines Process C in the two process model of sleep?

  • It creates the urge to sleep during periods of sleep deprivation.
  • It regulates sleep pressure based on adenosine levels.
  • It is responsible for circadian biological rhythms and melatonin secretion. (correct)
  • It enhances memory retention during sleep.
  • What unique characteristic is observed in avian NREM sleep in certain species?

  • Only one hemisphere of the brain sleeps while the other remains alert. (correct)
  • Prolonged periods of REM sleep compared to NREM.
  • Continuous alternation between NREM and REM without cycles.
  • Complete muscle paralysis during sleep.
  • How does sleep typically change from childhood into old age?

  • Increased overall sleep duration and stable REM sleep.
  • Decreased REM sleep, decreased SWS, and increased night awakenings. (correct)
  • Stable patterns of sleep spindle density across all ages.
  • The need for sleep diminishes significantly as one ages.
  • What finding did Barrett Klein's research reveal about sleep in bees?

    <p>Bees have a circadian rhythm influencing their sleep patterns with reduced muscle tone.</p> Signup and view all the answers

    What is the stable ratio of NREM to REM sleep in adults?

    <p>4(NREM):1(REM)</p> Signup and view all the answers

    What physiological signal is primarily measured in polysomnography (PSG) to assess sleep stages?

    <p>Electromyography</p> Signup and view all the answers

    Which stage of sleep is characterized by the presence of K-complexes and sleep spindles?

    <p>NREM Stage 2</p> Signup and view all the answers

    Which of the following neurotransmitters is at its highest level during REM sleep?

    <p>Acetylcholine</p> Signup and view all the answers

    What does the term 'zeitgeber' refer to in the context of circadian rhythms?

    <p>An external cue that influences the circadian clock</p> Signup and view all the answers

    During which state are the primary neuromodulators regulating sleep/wake most imbalanced?

    <p>Wakefulness</p> Signup and view all the answers

    What aspect of circadian rhythms makes them considered 'endogenous'?

    <p>They persist even in the absence of external cues.</p> Signup and view all the answers

    Which state of sleep is characterized by low muscle tone, absence of eye movements, and fast EEG activity?

    <p>REM sleep</p> Signup and view all the answers

    What is jet-lag, and what is a consequence of it?

    <p>A disruption of the biological clock causing misaligned circadian rhythms.</p> Signup and view all the answers

    Study Notes

    Polysomnography (PSG)

    • PSG is a method of measuring sleep
    • It uses three main signals: EEG, EOG, EMG
    • EEG measures brain electrical activity
    • EOG measures eye movements
    • EMG measures muscle activity

    Sleep Stages and Patterns

    • NREM 3 & 4 are considered 'slow wave sleep'
    • REM sleep involves no muscle tone, eye movements, and desynchronized brain waves
    • NREM Stage 2 includes K-complexes and sleep spindles
    • NREM-REM cycle in humans is ~90 minutes long

    Neurochemicals and Sleep/Wake Regulation

    • Wakefulness is associated with high frequency, low amplitude brainwaves
    • During wakefulness, 3 primary neuromodulators are in equilibrium
    • Neuromodulators are: Acetylcholine (ACh), norepinephrine (NE), and serotonin (5HT)
    • NREM: Acetylcholine is decreased, as are NE and 5HT
    • REM: NE and 5HT are at the lowest levels, while ACh is highest
    • Brainstem, thalamus, and cortex are involved in regulating sleep/wake states
    • The lateral prefrontal cortex is inactive during REM sleep
    • PGO waves are associated with rapid eye movements and scene changes in dreams

    Circadian Rhythms and Sleep

    • Circadian rhythms are "endogenous"
    • They persist without external cues, seen in the Mammoth Cave study
    • Melatonin is released in response to darkness and helps regulate sleep onset
    • Zeitgebers are external cues that reset the circadian clock
    • Examples of zeitgebers: Light, activity, food, temperature, social cues
    • Jet lag is a mismatch between biological clock and day/night cycle
    • This can cause disorganized and misaligned circadian rhythms
    • Two-process model of sleep:
      • Process C: the circadian process that regulates biological rhythms
      • Process S: sleep homeostasis regulated by sleep pressure

    Animal Sleep

    • All animals sleep
    • Bees have a state of reduced activity with reduced muscle tone
    • This state follows a circadian rhythm
    • Birds exhibit unihemispheric slow wave sleep (SWS)
    • This involves one hemisphere being in NREM while the other is awake
    • Unihemispheric SWS is also seen in humans in new sleeping settings

    Sleep Across the Lifespan

    • Infant sleep is polyphasic, with more REM and more sleep than adults
    • Sleep changes with age:
      • Decreased REM sleep
      • Decreased SWS
      • More night awakenings
    • Stable NREM:REM ratio in adults is 4:1
    • Increased sleep spindle density during naps improves memory retention and reduces forgetting in children
    • While older adults receive less sleep than younger adults, they still need the same amount of sleep

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    Description

    This quiz covers the fundamentals of polysomnography (PSG) and the cycles of sleep stages, including NREM and REM periods. Learn about the neurochemicals involved in wake and sleep regulation, and the physiological signals measured during sleep studies. Test your understanding of the complex interactions that dictate our sleep patterns.

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