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Platelet Membrane System and Function Quiz
10 Questions
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Platelet Membrane System and Function Quiz

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Questions and Answers

What key part of primary hemostasis involves platelet to platelet interaction?

  • Flipping phosphatidylserine to the outer layer
  • Losing shape and extending pseudopods
  • Releasing ADP and TXA2
  • Promoting platelet aggregation (correct)

    • What is the role of P-selectin in platelet aggregation?

  • Promoting platelet aggregation (correct)
  • Promoting release of granular contents
  • Enhancing the assembly of all BB3
  • Causing platelets to lose shape and extend pseudopods

    • What happens to phosphatidylserine during platelet aggregation?

  • It extends pseudopods and loses its shape
  • It is flipped to the outer layer (correct)
  • It is released and promotes assembly of all BB3
  • It triggers actin microfilament contraction

    • Which receptor is associated with substrate Fibrinogen in platelet aggregation?

    <p>GPllb- llla</p> Signup and view all the answers

    What triggers the 'outside-in activation' and release of granular contents in activated platelets?

    <p>Binding of integrins</p> Signup and view all the answers

    Which pathway promotes the release of ionic calcium from phospholipase A2 in platelet activation?

    <p>Inositol Triphosphate Activation Pathway</p> Signup and view all the answers

    What role does Inositol triphosphate (IP3) play in platelet activation?

    <p>Promotes release of ionic calcium from phospholipase A2</p> Signup and view all the answers

    Which receptor activates the extrinsic pathway of coagulation leading to thrombin activation and subsequent platelet activation?

    <p>Factor III - Tissue factor</p> Signup and view all the answers

    What is the main role of G-proteins in platelet activation?

    <p>Controlling cellular activation through heterotrimers</p> Signup and view all the answers

    What is the function of eicosanoid pathway in platelet activation?

    <p>Releasing vasoconstrictors from dense granules</p> Signup and view all the answers

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