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Platelet Membrane System and Function Quiz

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Platelet Membrane System and Function Quiz

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Questions and Answers

What key part of primary hemostasis involves platelet to platelet interaction?

Flipping phosphatidylserine to the outer layer

Losing shape and extending pseudopods

Releasing ADP and TXA2

Promoting platelet aggregation (correct)

What is the role of P-selectin in platelet aggregation?

Promoting platelet aggregation (correct)

Promoting release of granular contents

Enhancing the assembly of all BB3

Causing platelets to lose shape and extend pseudopods

What happens to phosphatidylserine during platelet aggregation?

It extends pseudopods and loses its shape

It is flipped to the outer layer (correct)

It is released and promotes assembly of all BB3

It triggers actin microfilament contraction

Which receptor is associated with substrate Fibrinogen in platelet aggregation?

GPllb- llla Signup and view all the answers

What triggers the 'outside-in activation' and release of granular contents in activated platelets?

Binding of integrins Signup and view all the answers

Which pathway promotes the release of ionic calcium from phospholipase A2 in platelet activation?

Inositol Triphosphate Activation Pathway Signup and view all the answers

What role does Inositol triphosphate (IP3) play in platelet activation?

Promotes release of ionic calcium from phospholipase A2 Signup and view all the answers

Which receptor activates the extrinsic pathway of coagulation leading to thrombin activation and subsequent platelet activation?

Factor III - Tissue factor Signup and view all the answers

What is the main role of G-proteins in platelet activation?

Controlling cellular activation through heterotrimers Signup and view all the answers

What is the function of eicosanoid pathway in platelet activation?

Releasing vasoconstrictors from dense granules Signup and view all the answers