Plasma Cells and Bone Marrow Quiz

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Questions and Answers

What is the primary origin of plasma cells?

  • Bone marrow
  • Lymph nodes (correct)
  • Thymus
  • Spleen

Where do plasma cells primarily home shortly after their formation?

  • Thymus
  • Spleen
  • Bone marrow (correct)
  • Lymph nodes

What percentage of all nucleated marrow cells do plasma cells comprise?

  • 3%
  • 2%
  • 1%
  • 4% (correct)

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Study Notes

Plasma Cell Origin and Distribution

  • Primary origin of plasma cells is from B cells in the lymphoid organs, particularly in the germinal centers of secondary lymphoid organs.
  • Shortly after their formation, plasma cells primarily home to the bone marrow, where they mature and produce large amounts of antibodies.
  • Plasma cells comprise approximately 5% of all nucleated marrow cells in a healthy adult.

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