Picornavirus: Coxsackie Viruses and Associated Diseases
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Questions and Answers

How is Hepatitis A virus transmitted?

  • Through blood transfusion
  • Through fecal-oral route (correct)
  • Through vector borne transmission
  • Through respiratory droplets
  • What is the primary mode of transmission of Poliovirus?

  • Through fecal-oral route (correct)
  • Through insect bite
  • Through respiratory droplets
  • Through contaminated water
  • What is the result of the death of motor neurons in Poliovirus infection?

  • Myocarditis
  • Aseptic meningitis
  • Hepatitis
  • Paralysis (correct)
  • What type of immune response is induced by the Sabin vaccine?

    <p>Mucosal immunity</p> Signup and view all the answers

    What is the primary target of immune attack in Hepatitis A virus infection?

    <p>Hepatocytes</p> Signup and view all the answers

    What is the characteristic of viremia in Hepatitis A virus infection?

    <p>Brief and low titer</p> Signup and view all the answers

    What is the primary route of transmission for Coxsackie viruses?

    <p>Fecal-oral route</p> Signup and view all the answers

    What is the main site of infection for Coxsackie viruses?

    <p>Gastrointestinal tract</p> Signup and view all the answers

    What is a common disease caused by Rhinoviruses?

    <p>The common cold</p> Signup and view all the answers

    What is a possible complication of Coxsackie virus B4 infection?

    <p>Juvenile diabetes</p> Signup and view all the answers

    Why are Rhinoviruses destroyed in the stomach?

    <p>Due to stomach acid</p> Signup and view all the answers

    What is the primary mechanism of immune response to Picornavirus infection?

    <p>Humoral immunity</p> Signup and view all the answers

    What is the goal of using alpha interferon and lamivudine in treating chronic hepatitis B?

    <p>To reduce inflammation associated with chronic hepatitis B</p> Signup and view all the answers

    What is the component used as an immunogen in the hepatitis B vaccine?

    <p>HBsAg</p> Signup and view all the answers

    Which of the following viruses is NOT an RNA virus with a linear, non-segmented, positive polarity genome?

    <p>Influenza virus</p> Signup and view all the answers

    What is the range of responses to poliovirus infection?

    <p>Inapparent, asymptomatic infection, abortive poliomyelitis, nonparalytic poliomyelitis, and paralytic poliomyelitis</p> Signup and view all the answers

    What is the classification of the virus that causes the common cold?

    <p>Rhinovirus</p> Signup and view all the answers

    What is unique about the genome of Retroviruses?

    <p>It has two identical strands of RNA (diploid)</p> Signup and view all the answers

    Study Notes

    Hepatitis A Virus Transmission

    • The Hepatitis A virus is primarily transmitted through the fecal-oral route. This means the virus is spread through contact with contaminated food or water, or through direct contact with an infected person.

    Poliovirus Transmission

    • The primary mode of transmission for Poliovirus is through the fecal-oral route. It spreads through contaminated water and food, or close contact with infected individuals.

    Poliovirus Infection and Motor Neuron Death

    • The death of motor neurons in Poliovirus infection leads to paralysis, primarily affecting the limbs and respiratory muscles.

    Sabin Vaccine and Immune Response

    • The Sabin vaccine induces a humoral immune response, meaning it stimulates the production of antibodies that circulate in the bloodstream and protect against future infection.

    Immune Target in Hepatitis A Virus Infection

    • The primary target of immune attack in Hepatitis A virus infection is the liver.

    Viremia in Hepatitis A Virus Infection

    • Viremia in Hepatitis A virus infection is brief and transient. This means the virus circulates in the bloodstream for a short duration.

    Coxsackie Virus Transmission

    • The primary route of transmission for Coxsackie viruses is through the fecal-oral route.

    Coxsackie Virus Infection Site

    • Coxsackie viruses primarily infect the gastrointestinal tract.

    Rhinoviruses and Common Cold

    • A common disease caused by Rhinoviruses is the common cold.

    Coxsackie Virus B4 Complication

    • A possible complication of Coxsackie virus B4 infection is myocarditis, an inflammation of the heart muscle.

    Rhinovirus Destruction in Stomach

    • Rhinoviruses are destroyed in the stomach due to its acidic environment.

    Immune Response to Picornavirus Infection

    • The primary mechanism of immune response to Picornavirus infection is the production of antibodies.

    Treatment of Chronic Hepatitis B

    • Alpha interferon and lamivudine are used in treating chronic hepatitis B with the goal of suppressing viral replication and reducing liver damage.

    Hepatitis B Vaccine Immunogen

    • The component used as an immunogen in the hepatitis B vaccine is the Hepatitis B surface antigen (HBsAg).

    Non-RNA Virus with Linear Genome

    • The virus that does NOT belong to the group of RNA viruses with a linear, non-segmented, positive polarity genome is Hepatitis B virus. It is a DNA virus.

    Poliovirus Infection Responses

    • The range of responses to poliovirus infection varies. Some individuals may experience no symptoms or mild symptoms, while others may develop paralysis.

    Common Cold Virus Classification

    • The virus that causes the common cold, a Rhinovirus, belongs to the Picornaviridae family.

    Retrovirus Genome Uniqueness

    • The genome of Retroviruses is unique because it's composed of RNA but can be reverse transcribed into DNA.

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    Description

    Learn about the administration of immune globulin during the incubation period of Picornavirus, specifically Coxsackie Viruses, and the diseases they cause, including aseptic meningitis, myocarditis, and hand, foot, and mouth disease.

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