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CNS Infections: Poliovirus and Coxsackie Quiz

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24 Questions

What is the clinical feature that distinguishes aseptic meningitis from bacterial meningitis?

Normal cerebral function

Which virus is a leading cause of viral meningitis from the Picornaviridae family?

Enterovirus 71

What is a common symptom of acute meningitis characterized by headache, neck stiffness, vomiting, and photophobia?

Coma

Which population is most susceptible to viral infections causing aseptic meningitis?

Neonates

What parameter in the CSF sample is typically abnormal in cases of bacterial meningitis?

Low glucose levels

Which type of meningitis is described as acute community-acquired with negative CSF gram stain and culture?

Viral meningitis

Which viral infection causes symptoms such as urinary retention, dysaesthesia, and neuralgia?

Herpes simplex virus (HSV)

Which virus is a member of the Picornaviridae family and primarily targets anterior horn cells?

Poliovirus

Which of the following is NOT one of the symptoms of viral meningitis mentioned in the text?

Respiratory tract symptoms

Which type of viral infection typically shows elevated white blood cell count (WBC), mildly elevated protein, and normal or mildly reduced glucose in diagnostic tests?

Viral meningitis

Which country is NOT listed as one where polio transmission has never been interrupted?

Iraq

Which statement accurately describes poliovirus transmission?

'Infection by one confers protective immunity ONLY to that type'

What is the typical duration of the 'minor illness' phase in poliovirus infection?

2-3 days

Which group is at a significantly higher risk of developing OPV-associated disease?

Prepubertal males with B-cell deficiency

Which phase of poliovirus infection involves the development of type-specific antibodies?

Asymptomatic stage

Which of the following is NOT a risk factor for paralysis in poliovirus infection?

IM injections during the minor illness phase

Which neurological structures are most commonly affected by poliovirus infections?

Neurons throughout the grey matter of the spinal cord and motor nuclei of the medulla and pons

What percentage of poliovirus infections results in frank paralysis?

0.1%

Which of the following complications of polio involves muscle paralysis?

Respiratory compromise due to diaphragmatic and intercostal muscle paralysis

Which of the following viruses is NOT a differential diagnosis for polio?

Ebola

Which of the following tests is the gold standard for identifying poliovirus?

Viral identification by PCR or culture in CSF

Which of the following is NOT a recommended treatment for polio?

Specific antiviral therapy

Which of the following viruses can cause polio-like permanent paralysis?

Coxsackievirus A7

Which of the following is NOT a common symptom of polio?

Nausea and vomiting

Test your knowledge on the common causes of bacterial vs viral meningitis, viral structure, clinical effects, transmission, and patient populations of poliovirus and Coxsackie virus. Explore information on available vaccines and the symptoms of acute meningitis.

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