CNS Infections: Poliovirus and Coxsackie Quiz
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Questions and Answers

What is the clinical feature that distinguishes aseptic meningitis from bacterial meningitis?

  • Positive CSF gram stain
  • Presence of fever
  • Altered mental status
  • Normal cerebral function (correct)

Which virus is a leading cause of viral meningitis from the Picornaviridae family?

  • HSV2
  • Rhinovirus
  • Enterovirus 71 (correct)
  • Arbovirus

What is a common symptom of acute meningitis characterized by headache, neck stiffness, vomiting, and photophobia?

  • Confusion
  • Rash
  • Lethargy
  • Coma (correct)

Which population is most susceptible to viral infections causing aseptic meningitis?

<p>Neonates (C)</p> Signup and view all the answers

What parameter in the CSF sample is typically abnormal in cases of bacterial meningitis?

<p>Low glucose levels (D)</p> Signup and view all the answers

Which type of meningitis is described as acute community-acquired with negative CSF gram stain and culture?

<p>Viral meningitis (D)</p> Signup and view all the answers

Which viral infection causes symptoms such as urinary retention, dysaesthesia, and neuralgia?

<p>Herpes simplex virus (HSV) (D)</p> Signup and view all the answers

Which virus is a member of the Picornaviridae family and primarily targets anterior horn cells?

<p>Poliovirus (B)</p> Signup and view all the answers

Which of the following is NOT one of the symptoms of viral meningitis mentioned in the text?

<p>Respiratory tract symptoms (D)</p> Signup and view all the answers

Which type of viral infection typically shows elevated white blood cell count (WBC), mildly elevated protein, and normal or mildly reduced glucose in diagnostic tests?

<p>Viral meningitis (B)</p> Signup and view all the answers

Which country is NOT listed as one where polio transmission has never been interrupted?

<p>Iraq (B)</p> Signup and view all the answers

Which statement accurately describes poliovirus transmission?

<p>'Infection by one confers protective immunity ONLY to that type' (C)</p> Signup and view all the answers

What is the typical duration of the 'minor illness' phase in poliovirus infection?

<p>2-3 days (D)</p> Signup and view all the answers

Which group is at a significantly higher risk of developing OPV-associated disease?

<p>Prepubertal males with B-cell deficiency (C)</p> Signup and view all the answers

Which phase of poliovirus infection involves the development of type-specific antibodies?

<p>Asymptomatic stage (D)</p> Signup and view all the answers

Which of the following is NOT a risk factor for paralysis in poliovirus infection?

<p>IM injections during the minor illness phase (D)</p> Signup and view all the answers

Which neurological structures are most commonly affected by poliovirus infections?

<p>Neurons throughout the grey matter of the spinal cord and motor nuclei of the medulla and pons (C)</p> Signup and view all the answers

What percentage of poliovirus infections results in frank paralysis?

<p>0.1% (B)</p> Signup and view all the answers

Which of the following complications of polio involves muscle paralysis?

<p>Respiratory compromise due to diaphragmatic and intercostal muscle paralysis (C)</p> Signup and view all the answers

Which of the following viruses is NOT a differential diagnosis for polio?

<p>Ebola (A)</p> Signup and view all the answers

Which of the following tests is the gold standard for identifying poliovirus?

<p>Viral identification by PCR or culture in CSF (D)</p> Signup and view all the answers

Which of the following is NOT a recommended treatment for polio?

<p>Specific antiviral therapy (A)</p> Signup and view all the answers

Which of the following viruses can cause polio-like permanent paralysis?

<p>Coxsackievirus A7 (A)</p> Signup and view all the answers

Which of the following is NOT a common symptom of polio?

<p>Nausea and vomiting (C)</p> Signup and view all the answers

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