CNS Infections: Poliovirus and Coxsackie Quiz
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Questions and Answers

Which virus causes paralytic disease mainly targeting anterior horn cells?

  • Mumps virus
  • Herpes simplex virus (HSV)
  • Poliovirus (correct)
  • Influenza virus
  • What is the transmission route mainly associated with Poliovirus?

  • Respiratory droplets
  • Blood transfusion
  • Sexual contact
  • Faeco-oral (correct)
  • Which of the following viruses causes symptoms such as urinary retention, dysaesthesia, paraesthesiae, neuralgia, and motor weakness?

  • HIV
  • Herpes simplex virus (HSV) (correct)
  • Rabies virus
  • West Nile virus
  • What is the family to which Poliovirus belongs?

    <p>Picornaviridae</p> Signup and view all the answers

    Which age group is most commonly affected by Poliovirus infection?

    <p>Children aged 5-9 years</p> Signup and view all the answers

    What is the main target tissue of Poliovirus during epidemics?

    <p>Nervous system tissues</p> Signup and view all the answers

    Where does the CNS become infected in poliovirus cases?

    <p>Medulla and pons</p> Signup and view all the answers

    What is the incubation period for poliovirus from acquisition to prodrome?

    <p>8-12 days</p> Signup and view all the answers

    What are the risk factors for paralysis in poliovirus cases?

    <p>Tonsillectomy</p> Signup and view all the answers

    What percentage of poliovirus infections experience just the prodrome before becoming non-paralytic polio?

    <p>4-8%</p> Signup and view all the answers

    Which part of the body is most at risk for paralysis following IM injections in poliovirus cases?

    <p>Limb injected or injured</p> Signup and view all the answers

    What determines the clinical disease severity in cases of poliovirus infection?

    <p>Distribution of lesions</p> Signup and view all the answers

    Which of the following is a common clinical feature of aseptic meningitis?

    <p>Headache and neck stiffness</p> Signup and view all the answers

    What is the main characteristic of CSF findings in bacterial meningitis?

    <p>Neutrophil-predominant WBCs</p> Signup and view all the answers

    Which virus is not commonly associated with causing viral meningitis?

    <p>Influenza virus</p> Signup and view all the answers

    What is a distinguishing feature of aseptic meningitis compared to bacterial meningitis?

    <p>Presence of rash</p> Signup and view all the answers

    What is a common feature of viral meningitis caused by Picornaviridae viruses?

    <p>Mononuclear-predominant WBCs in CSF</p> Signup and view all the answers

    Which age group is more likely to present with insidious symptoms of bacterial meningitis?

    <p>Elderly</p> Signup and view all the answers

    What is the gold standard for diagnosing Polio?

    <p>CSF viral identification by PCR or culture</p> Signup and view all the answers

    Why is it important to identify the viral strain in areas of low Polio incidence?

    <p>To differentiate between wild-type and vaccine-related strains</p> Signup and view all the answers

    What is the most appropriate management for Polio?

    <p>Supportive care</p> Signup and view all the answers

    Which of the following symptoms is NOT associated with Polio?

    <p>Respiratory centre hyperactivity</p> Signup and view all the answers

    What is a common complication of Polio involving paralysis of the diaphragm and intercostal muscles?

    <p>Respiratory compromise</p> Signup and view all the answers

    In Polio diagnosis, where is the virus most likely to be detected in the first week of illness?

    <p>Throat sample</p> Signup and view all the answers

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