CNS Infections: Poliovirus and Coxsackie Quiz
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Questions and Answers

Which virus causes paralytic disease mainly targeting anterior horn cells?

  • Mumps virus
  • Herpes simplex virus (HSV)
  • Poliovirus (correct)
  • Influenza virus

What is the transmission route mainly associated with Poliovirus?

  • Respiratory droplets
  • Blood transfusion
  • Sexual contact
  • Faeco-oral (correct)

Which of the following viruses causes symptoms such as urinary retention, dysaesthesia, paraesthesiae, neuralgia, and motor weakness?

  • HIV
  • Herpes simplex virus (HSV) (correct)
  • Rabies virus
  • West Nile virus

What is the family to which Poliovirus belongs?

<p>Picornaviridae (D)</p> Signup and view all the answers

Which age group is most commonly affected by Poliovirus infection?

<p>Children aged 5-9 years (B)</p> Signup and view all the answers

What is the main target tissue of Poliovirus during epidemics?

<p>Nervous system tissues (C)</p> Signup and view all the answers

Where does the CNS become infected in poliovirus cases?

<p>Medulla and pons (B)</p> Signup and view all the answers

What is the incubation period for poliovirus from acquisition to prodrome?

<p>8-12 days (D)</p> Signup and view all the answers

What are the risk factors for paralysis in poliovirus cases?

<p>Tonsillectomy (C)</p> Signup and view all the answers

What percentage of poliovirus infections experience just the prodrome before becoming non-paralytic polio?

<p>4-8% (C)</p> Signup and view all the answers

Which part of the body is most at risk for paralysis following IM injections in poliovirus cases?

<p>Limb injected or injured (C)</p> Signup and view all the answers

What determines the clinical disease severity in cases of poliovirus infection?

<p>Distribution of lesions (B)</p> Signup and view all the answers

Which of the following is a common clinical feature of aseptic meningitis?

<p>Headache and neck stiffness (C)</p> Signup and view all the answers

What is the main characteristic of CSF findings in bacterial meningitis?

<p>Neutrophil-predominant WBCs (C)</p> Signup and view all the answers

Which virus is not commonly associated with causing viral meningitis?

<p>Influenza virus (D)</p> Signup and view all the answers

What is a distinguishing feature of aseptic meningitis compared to bacterial meningitis?

<p>Presence of rash (B)</p> Signup and view all the answers

What is a common feature of viral meningitis caused by Picornaviridae viruses?

<p>Mononuclear-predominant WBCs in CSF (C)</p> Signup and view all the answers

Which age group is more likely to present with insidious symptoms of bacterial meningitis?

<p>Elderly (A)</p> Signup and view all the answers

What is the gold standard for diagnosing Polio?

<p>CSF viral identification by PCR or culture (C)</p> Signup and view all the answers

Why is it important to identify the viral strain in areas of low Polio incidence?

<p>To differentiate between wild-type and vaccine-related strains (A)</p> Signup and view all the answers

What is the most appropriate management for Polio?

<p>Supportive care (D)</p> Signup and view all the answers

Which of the following symptoms is NOT associated with Polio?

<p>Respiratory centre hyperactivity (C)</p> Signup and view all the answers

What is a common complication of Polio involving paralysis of the diaphragm and intercostal muscles?

<p>Respiratory compromise (A)</p> Signup and view all the answers

In Polio diagnosis, where is the virus most likely to be detected in the first week of illness?

<p>Throat sample (A)</p> Signup and view all the answers

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