Chapter 44
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Chapter 44

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Questions and Answers

What is a major risk associated with NSAIDs?

  • Altered hemostasis (correct)
  • Increased appetite
  • Increased energy levels
  • Decreased risk of stroke

    • Which of the following conditions is a contraindication for NSAID use?

  • Asthma
  • Hypertension
  • Type 1 Diabetes
  • Peptic ulcer disease (correct)

    • What is the purpose of Misoprostol when used with NSAIDs?

  • To reduce cardiovascular risks
  • To increase the efficacy of NSAIDs
  • To enhance renal function
  • To prevent gastrointestinal bleeding (correct)

    • Which statement accurately reflects the cardiovascular risk associated with NSAIDs?

    <p>They increase the risk of adverse cardiovascular thrombotic events.</p> Signup and view all the answers

    NSAIDs can disrupt which physiological function that is crucial for renal health?

    <p>Prostaglandin function</p> Signup and view all the answers

    What therapeutic effect does aspirin provide at dosages of 81 mg or 325 mg?

    <p>Thromboprevention</p> Signup and view all the answers

    What complication can result from the use of NSAIDs in patients with dehydrated conditions?

    <p>Renal toxicity</p> Signup and view all the answers

    Which class of drug is considered an exception for the cardiovascular black box warning associated with NSAIDs?

    <p>Aspirin</p> Signup and view all the answers

    What is Reye's syndrome primarily associated with?

    <p>Salicylate therapy during viral illnesses</p> Signup and view all the answers

    What neurological effects can result from Reye's syndrome?

    <p>Permanent neurologic damage</p> Signup and view all the answers

    Which of the following is NOT a symptom of salicylate toxicity?

    <p>Weight gain</p> Signup and view all the answers

    What is the primary therapeutic use of ketorolac (Toradol)?

    <p>Short-term management of moderate to severe acute pain</p> Signup and view all the answers

    What is a significant risk when using ketorolac for more than 5 days?

    <p>Severe renal and GI effects</p> Signup and view all the answers

    What condition is ibuprofen primarily used to treat?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    Which of the following is NOT a common side effect of ketorolac?

    <p>Severe dizziness</p> Signup and view all the answers

    Which drug is used as an antidote for acetaminophen overdose?

    <p>Acetylcysteine</p> Signup and view all the answers

    Which of the following substances is NOT considered an endogenous compound involved in inflammation?

    <p>Aspirin</p> Signup and view all the answers

    What is one of the primary roles of COX-1 in the body?

    <p>Maintenance of GI mucosa</p> Signup and view all the answers

    Which nonsteroidal anti-inflammatory drug (NSAID) is known for its irreversible inhibition of COX-1?

    <p>Aspirin</p> Signup and view all the answers

    Which of the following is NOT considered a property of NSAIDs?

    <p>Immunosuppressive</p> Signup and view all the answers

    What effect do nonsteroidal anti-inflammatory drugs have on thromboxane A2 levels?

    <p>Inhibit formation of thromboxane A2</p> Signup and view all the answers

    Which drug class includes ibuprofen and naproxen?

    <p>Propionic Acid Derivatives</p> Signup and view all the answers

    In the context of myocardial infarction (MI), why is aspirin specifically administered?

    <p>To reduce cardiac death</p> Signup and view all the answers

    Which of the following NSAIDs is a derivative of acetic acid?

    <p>Ketorolac</p> Signup and view all the answers

    What is the primary therapeutic indication for Celecoxib (Celebrex)?

    <p>Osteoarthritis and rheumatoid arthritis</p> Signup and view all the answers

    Which of the following is considered a common adverse effect of NSAIDs?

    <p>Dyspepsia and heartburn</p> Signup and view all the answers

    In which situation should Ibuprofen be used with caution?

    <p>In patients with renal impairment</p> Signup and view all the answers

    What is the primary action of Allopurinol in the management of gout?

    <p>Prevents uric acid production</p> Signup and view all the answers

    Which type of adverse effect is specifically associated with Colchicine?

    <p>Leukopenia</p> Signup and view all the answers

    What should patients be advised not to do with enteric-coated tablets?

    <p>Crush or chew them</p> Signup and view all the answers

    What significant interaction does alcohol have concerning NSAID use?

    <p>Increased chance of gastrointestinal bleeding</p> Signup and view all the answers

    What is a potential consequence of treating children with salicylates?

    <p>Reye's syndrome</p> Signup and view all the answers

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