NSAIDs Pharmacology
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Questions and Answers

What is pain?

  • An unpleasant sensation that can range from mild, localized discomfort to agony. (correct)
  • A localized physical discomfort
  • An emotional response to injury
  • A response to nerve stimulation.

What is the primary cause of nociceptive pain?

  • Inflammation of the affected area
  • Direct stimulation of peripheral nerve endings by a noxious stimulus (correct)
  • Damage to nerve endings
  • Psychological factors such as anxiety and fear

What type of pain is characterized by diffuse discomfort, as seen in disorders like fibromyalgia?

  • Visceral pain
  • Neuropathic pain
  • Nociceptive pain (correct)
  • Somatic pain

What are the two main types of pain classified?

<p>Nociceptive and neuropathic (B)</p> Signup and view all the answers

What is not a characteristic of pain?

<p>Pleasant sensation (B)</p> Signup and view all the answers

What is the primary objective of learning outcome number 3?

<p>To explain the pharmacological actions of NSAIDs (C)</p> Signup and view all the answers

What is the common indication for the contraindication of non-selective COX inhibitors in patients with peptic ulcer?

<p>Gastrointestinal toxicity (A)</p> Signup and view all the answers

What is the primary objective of learning outcome number 7?

<p>To choose an appropriate NSAID for a given clinical condition (C)</p> Signup and view all the answers

What is the primary objective of learning outcome number 9?

<p>To apply the toxicokinetics of paracetamol and pathology of paracetamol poisoning (C)</p> Signup and view all the answers

Which of the following is NOT a condition where non-selective COX inhibitors are contraindicated?

<p>Children above 18 years of age (A)</p> Signup and view all the answers

What is the primary objective of learning outcome number 10?

<p>To list topical NSAIDs and analgesic combinations used in pain management (D)</p> Signup and view all the answers

What is paracetamol preferred for in reducing elevated body temperature in fever?

<p>Because it does not cause GI symptoms and doesn't cause Reye's syndrome in children (A)</p> Signup and view all the answers

What is used in mild cases of osteoarthritis?

<p>Paracetamol (C)</p> Signup and view all the answers

What is the drug of choice for acute rheumatic fever?

<p>Aspirin (D)</p> Signup and view all the answers

What is used to prevent cardiac complications in acute rheumatic fever?

<p>Long-acting penicillin (D)</p> Signup and view all the answers

What is the drug of choice in thromboembolic disorders?

<p>Aspirin (D)</p> Signup and view all the answers

What is used to close a patent ductus arteriosus (PDA)?

<p>Indomethacin or ibuprofen (A)</p> Signup and view all the answers

Why are salicylates contraindicated in children below 15 years?

<p>Because they can cause severe toxicity in children with viral fever (A)</p> Signup and view all the answers

What is the preferred medication in children?

<p>Paracetamol (B)</p> Signup and view all the answers

What is the effect of therapeutic dose aspirin on respiration?

<p>It stimulates respiration and produces hyperventilation (A)</p> Signup and view all the answers

What is the characteristic of salicylism?

<p>Headache, vertigo, tinnitus, hyperventilation, nausea, and vomiting (C)</p> Signup and view all the answers

What is the effect of a plasma level of 500 microgram to 1 mg of aspirin?

<p>It causes respiratory acidosis (A)</p> Signup and view all the answers

What is the potential consequence of chronic consumption of aspirin and other NSAIDs?

<p>Irreversible renal damage (D)</p> Signup and view all the answers

Why should NSAIDs be avoided in asthmatics?

<p>Due to increased production of leukotrienes (D)</p> Signup and view all the answers

What is a potential consequence of taking NSAIDs near term?

<p>Increased chances of post-partum hemorrhage (A)</p> Signup and view all the answers

What is a potential consequence of long-term use of aspirin?

<p>Decreased prothrombin levels (C)</p> Signup and view all the answers

What is the effect of aspirin on uric acid excretion?

<p>Decreases uric acid excretion (D)</p> Signup and view all the answers

What is a potential consequence of using aspirin in children with viral infections?

<p>Reye's syndrome (D)</p> Signup and view all the answers

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