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Pharmacology Quiz: Alpha Blockers and Vasodilators

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Pharmacology Quiz: Alpha Blockers and Vasodilators

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Questions and Answers

What is the mechanism of action of Sodium Nitroprusside?

Activates dopamine D1 receptors

Opens K+ channels in smooth muscle

Blocks insulin release

Increases cGMP to relax smooth muscle (correct)

What is a common side effect of Minoxidil?

Hyperglycemia

Hirsutism (correct)

Anorexia

Reflex tachycardia

What is the initial step in managing Heart Failure?

Prescribe diuretics

Restrict dietary sodium

Reduce workload of the heart (correct)

Restrict water intake

What is the effect of Diazoxide on blood pressure?

Decreases blood pressure only in arteries Signup and view all the answers

What is the mechanism of action of Fenoldopam?

Agonist of dopamine D1 receptors Signup and view all the answers

Which of the following vasodilators is used for long-term treatment of hypertension?

Hydralazine Signup and view all the answers

What is the main mechanism of action of methyldopa in reducing blood pressure?

It binds to α-adrenoceptors to modulate baroreceptor reflexes Signup and view all the answers

What is a common side effect of clonidine that is less pronounced with the transdermal patch?

Sedation Signup and view all the answers

What is the consequence of missing one or two doses of clonidine?

Hypertensive emergency Signup and view all the answers

Which of the following drugs share the same mechanism of action as clonidine but offer no advantages?

Guanabenz and Guanfacine Signup and view all the answers

What is the primary effect of ganglion blockers on the nervous system?

They block nicotinic cholinoceptors in both sympathetic and parasympathetic ganglia Signup and view all the answers

Why have ganglion blockers largely been abandoned in clinical practice?

They cause excessive orthostatic hypotension and other side effects Signup and view all the answers

What is the effect of Propranolol on renin production?

Inhibits renin production Signup and view all the answers

What is the benefit of using Propranolol with direct vasodilators in severe hypertension?

Prevents reflex tachycardia Signup and view all the answers

What is the mechanism of action of Prazosin?

Blocks a1-receptors in arterioles and venules Signup and view all the answers