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Questions and Answers
What is the primary objective of the lecture on drugs acting on the skeletal muscle system?
What is the primary objective of the lecture on drugs acting on the skeletal muscle system?
- To discuss the pathophysiology of muscle diseases
- To discuss the physiology of the skeletal muscle system
- To discuss the pharmacology of some drugs used to induce skeletal muscle paralysis, increase muscle strength, and treat Spastic disorders (correct)
- To discuss the pharmacology of drugs used to treat neurological disorders
What type of channels are stimulated by the release of Ach in the muscle?
What type of channels are stimulated by the release of Ach in the muscle?
- Gamma-aminobutyric acid (GABA) receptors
- Nicotinic Na+ channels (correct)
- Muscarinic K+ channels
- Voltage-sensitive Ca2+ channels
What is the result of the stimulation of the channels by the neurotranmitter in the cleft?
What is the result of the stimulation of the channels by the neurotranmitter in the cleft?
- Development of endplate potential (correct)
- Inhibition of muscle contraction
- Hyperpolarization of the muscle fiber
- Stimulation of the muscle spindle
Through which channels is the depolarization propagated down the muscle?
Through which channels is the depolarization propagated down the muscle?
What is the name of the YouTube video linked in the text?
What is the name of the YouTube video linked in the text?
What is the email address of Professor M. Gossell-Williams?
What is the email address of Professor M. Gossell-Williams?
What is the primary mechanism of action of succinylcholine?
What is the primary mechanism of action of succinylcholine?
Which of the following muscle relaxants is metabolized by pseudocholinesterases?
Which of the following muscle relaxants is metabolized by pseudocholinesterases?
What is the primary clinical application of dantrolene?
What is the primary clinical application of dantrolene?
What is the duration of action of mivacurium?
What is the duration of action of mivacurium?
What is the adverse effect of succinylcholine that results in uncontrolled skeletal muscle hypermetabolism?
What is the adverse effect of succinylcholine that results in uncontrolled skeletal muscle hypermetabolism?
What is the route of administration of pancuronium?
What is the route of administration of pancuronium?
What is the primary mechanism of action of Baclofen in preventing skeletal muscle excitation-contraction coupling?
What is the primary mechanism of action of Baclofen in preventing skeletal muscle excitation-contraction coupling?
Which of the following medications is known to cause significant sedation?
Which of the following medications is known to cause significant sedation?
What is the primary route of administration for Baclofen?
What is the primary route of administration for Baclofen?
What is the primary mechanism of action of Pyridostigmine?
What is the primary mechanism of action of Pyridostigmine?
What is the primary elimination pathway for Pyridostigmine?
What is the primary elimination pathway for Pyridostigmine?
What is a common side effect of Dantrolene?
What is a common side effect of Dantrolene?
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