Y1S2 005 III Pharmacology of Skeletal Muscle Systems

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the primary function of the drugs used to induce skeletal muscle paralysis?

  • To increase muscle strength
  • To stimulate muscle contraction
  • To relax muscles during surgical procedures (correct)
  • To treat Spastic disorders

Which type of channels are stimulated by the release of Ach during AP propagation?

  • Voltage-sensitive K+ channels
  • Voltage-sensitive Ca2+ channels
  • Muscarinic receptors
  • Nicotinic Na+ channels (correct)

What is the term for the development of a potential difference across the muscle membrane during AP propagation?

  • Action potential
  • Threshold potential
  • Depolarization
  • Endplate potential (correct)

What is the primary mechanism of AP propagation down the muscle?

<p>Through the stimulation of voltage-sensitive Na+ channels (B)</p> Signup and view all the answers

What is the role of the neurotranmitter released by the nerve during AP propagation?

<p>To stimulate the development of endplate potential (D)</p> Signup and view all the answers

What is the term for the potential difference that stimulates the contraction of muscle fibers?

<p>Threshold potential (D)</p> Signup and view all the answers

What is the primary mechanism of action of Succinylcholine?

<p>Persistent depolarization inhibiting the passage of action potential through voltage sodium channel (B)</p> Signup and view all the answers

Which of the following muscle relaxants is metabolized by pseudocholinesterases?

<p>Succinylcholine and Mivacurium (C)</p> Signup and view all the answers

What is the primary clinical application of Dantrolene?

<p>To relieve the spasticity occurring with conditions such as cerebral palsy (D)</p> Signup and view all the answers

What is the duration of action of Mivacurium?

<p>Ultra-short (5-10 minutes) (C)</p> Signup and view all the answers

What is the adverse effect of Succinylcholine that is associated with genetic disorder of skeletal muscle calcium regulation?

<p>Malignant hyperthermia (A)</p> Signup and view all the answers

Which of the following is a non-depolarizing muscle relaxant?

<p>Pancuronium (A)</p> Signup and view all the answers

What is the primary action of Baclofen at the pre-synaptic and post-synaptic receptors in the spinal cord?

<p>Reduce motor neuron activation (A)</p> Signup and view all the answers

What is the primary route of administration for Dantrolene?

<p>Oral (C)</p> Signup and view all the answers

What is the primary effect of Pyridostigmine on acetylcholinesterase?

<p>Reversible inhibition (D)</p> Signup and view all the answers

What is the primary elimination route of Pyridostigmine?

<p>Renal (D)</p> Signup and view all the answers

What is a common adverse effect of Diazepam?

<p>Sedation (B)</p> Signup and view all the answers

What is the approximate half-life of Baclofen?

<p>3-4 hours (A)</p> Signup and view all the answers

Flashcards are hidden until you start studying

Related Documents

More Like This

Use Quizgecko on...
Browser
Browser