Podcast
Questions and Answers
What is a characteristic of vinblastine?
What is a characteristic of vinblastine?
- It can cause bradycardia, hypotension, and edema (correct)
- It is used to treat filariasis
- It is a mucolytic agent
- It is a proton pump inhibitor
What is not a component of Cluviscol tablets?
What is not a component of Cluviscol tablets?
- Lansoprazole (correct)
- Vitamin D2 400 IU
- Cobalt 3mg
- Ferrous fumarate 15mg
What is true about N-acetylcysteine?
What is true about N-acetylcysteine?
- It is marketed as Cellcept
- It is indicated for the treatment of paracetamol poisoning intravenously (correct)
- It is used as a mucolytic agent
- It is used to treat lymphatic obstructive disease
Which agent is used to eradicate microfilaria in filariasis?
Which agent is used to eradicate microfilaria in filariasis?
What is true about Cellcept?
What is true about Cellcept?
Which of the following is not a cell cycle phase-specific antineoplastic agent?
Which of the following is not a cell cycle phase-specific antineoplastic agent?
What is a side effect of vinblastine?
What is a side effect of vinblastine?
Which of the following is a cell cycle phase-specific antineoplastic agent?
Which of the following is a cell cycle phase-specific antineoplastic agent?
What is the primary reason for using drug combinations in the treatment of TB?
What is the primary reason for using drug combinations in the treatment of TB?
Which of the following antibiotics exerts synergistic effects with beta-lactam antibiotics?
Which of the following antibiotics exerts synergistic effects with beta-lactam antibiotics?
What is the mechanism of action of certain antibiotics that bind to the 50s ribosomal subunit?
What is the mechanism of action of certain antibiotics that bind to the 50s ribosomal subunit?
Why are Staphylococci resistant to methicillin often resistant to aminoglycosides?
Why are Staphylococci resistant to methicillin often resistant to aminoglycosides?
Which of the following is an important adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide?
Which of the following is an important adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide?
Which of the following anticancer drugs is cell cycle nonspecific?
Which of the following anticancer drugs is cell cycle nonspecific?
What is a common mechanism of resistance to certain antibiotics?
What is a common mechanism of resistance to certain antibiotics?
What is true about the drug Pritor?
What is true about the drug Pritor?
What is the result of chronic exposure to a certain metal?
What is the result of chronic exposure to a certain metal?
Which toxin is produced by puffer fish?
Which toxin is produced by puffer fish?
What is another name for dimercaprol?
What is another name for dimercaprol?
What is a mixture of copper and arsenic salt used to control insects in the 1800s?
What is a mixture of copper and arsenic salt used to control insects in the 1800s?
What is a natural compound derived from Urginea maritime that is effective in controlling rodents?
What is a natural compound derived from Urginea maritime that is effective in controlling rodents?
Which polycyclic aromatic hydrocarbon is found in cigarette smoke?
Which polycyclic aromatic hydrocarbon is found in cigarette smoke?
What is produced by the mold Fusarium solani that infects sweet potatoes?
What is produced by the mold Fusarium solani that infects sweet potatoes?
What is the toxin produced by the mold Aspergillus flavus?
What is the toxin produced by the mold Aspergillus flavus?
Which of the following is a dopaminergic anti-parkinson's agent?
Which of the following is a dopaminergic anti-parkinson's agent?
What is the mechanism of action of milrinone lactate?
What is the mechanism of action of milrinone lactate?
Which of the following is NOT a protease inhibitor?
Which of the following is NOT a protease inhibitor?
What is a characteristic of alteplase?
What is a characteristic of alteplase?
Which of the following is an antiviral drug?
Which of the following is an antiviral drug?
What is the mechanism of action of Zocor?
What is the mechanism of action of Zocor?
Which of the following is NOT a characteristic of milrinone lactate?
Which of the following is NOT a characteristic of milrinone lactate?
Which of the following is an aminopenicillin?
Which of the following is an aminopenicillin?
Which of the following substances is associated with hypocalcemia?
Which of the following substances is associated with hypocalcemia?
Which of the following drugs is a common cause of toxic epidermal necrolysis?
Which of the following drugs is a common cause of toxic epidermal necrolysis?
What is the CNS toxin found in Artemisia absinthuim?
What is the CNS toxin found in Artemisia absinthuim?
What is the primary indication for whole bowel irrigation in poisoned patients?
What is the primary indication for whole bowel irrigation in poisoned patients?
Which of the following alkaloids is found in Strychnos nux-vomica?
Which of the following alkaloids is found in Strychnos nux-vomica?
What is the primary mechanism of action of calcitonin?
What is the primary mechanism of action of calcitonin?
Which of the following is not a common cause of hypocalcemia?
Which of the following is not a common cause of hypocalcemia?
Study Notes
Thyrotropin
- Thyrotropin exerts synergistic effects with beta-lactam antibiotics against selected organisms.
- Thyrotropin's antibacterial action involves binding to the 50s ribosomal subunit and subsequent inhibition of peptidyltransferase.
Clinical Resistance
- Clinical resistance occurs through plasmid-mediated formation of group transferase-inactivating enzymes.
- Staphylococci resistant to methicillin are usually resistant to aminoglycosides.
Cancer Chemotherapy
- MESNA is an important adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide to prevent urotoxicity.
- Pritor is of the same therapeutic class and indication as Hypace and Diovan.
Antibiotics
- Cidofovir is a protease inhibitor.
- Acyclovir is not a protease inhibitor.
- Nelfinavir is a protease inhibitor.
Vasopressin and Somatomedin
- Vasopressin and somatomedin exert synergistic effects with beta-lactam antibiotics against selected organisms.
Cancer Treatment
- The primary reason for the use of drug combinations in the treatment of TB is to delay the emergence of resistance.
Antineoplastic Agents
- Daunorubucin is an antineoplastic agent.
- Vincristine is an antineoplastic agent.
Filariasis and Lymphatic Obstructive Disease
- Filariasis is caused by Wuchereria bancrofti and Brugia malayi.
- Eradication of the microfilaria can be accomplished by the use of diethylcarbamazine.
Anti-Parkinson's Agents
- Ropinerole is a dopaminergic anti-parkinson's agent.
- Pergolide is a dopaminergic anti-parkinson's agent.
Cell Cycle Phase-Specific Agent
- Vinblastine is a cell cycle phase-specific agent.
N-Acetylcysteine
- N-acetylcysteine is used as a mucolytic agent.
- It is marketed as Acetadote, Fluimucil, and Hidonac.
Cluviscol Tablets
- Cluviscol tablets contain Vitamin D2 400 IU, Calcium 120mg, Ferrous fumarate 15mg, and Vitamin C 150mg.
Cancer Chemotherapy and Adjuvants
- MESNA is an important adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide to prevent urotoxicity.
Toxins and Metals
- Chronic exposure to arsenic results in hyperpigmentation and hyperkeratosis of the palms and soles.
- Saxitoxin is a toxin produced by puffer fish.
Insecticides and Pesticides
- Bordeaux is a mixture of copper and arsenic salt that is used to control insects.
- Pyrethrin is a natural compound derived from Urginea maritime and is effective in controlling rodents.
Vitamins and Toxins
- Exposure to vitamin A can cause hypocalcemia.
Toxic Epidermal Necrolysis
- Medications are causally implicated in 80-90% of toxic epidermal necrolysis cases.
Overdose Management
- Whole bowel irrigation is the most effective process for evacuating the intestinal tract in poisoned patients.
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Description
This quiz covers the mechanisms of action and characteristics of antibiotics, including their effects on cellular processes and interactions with other medications.
