Beta-Lactam Antibiotics: Pharmacology and Therapeutics
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Questions and Answers

What is the action of β-lactam antibiotics on bacteria?

  • They dissolve cell wall structures, leading to rupture and death (correct)
  • They interfere with cell membrane integrity
  • They inhibit DNA replication
  • They prevent protein synthesis

    • Where are β-lactam antibiotics primarily excreted?

  • In the feces
  • In the urine (correct)
  • In the breath
  • In the sweat

    • What is the drug of choice for the initial treatment of infections in horses and cattle?

  • Vancomycin
  • Penicillin (correct)
  • Erythromycin
  • Tetracycline

    • What does '1 unit' of penicillin represent?

    <p>Amount of Na penicillin that gave a standard zone of inhibition on a standard culture medium</p> Signup and view all the answers

    Why are some penicillins dosed based on units or IU?

    <p>The amount of drug needed to produce the desired effect varies</p> Signup and view all the answers

    What is the target of β-lactam antibiotics?

    <p>Growing &amp; metabolically active bacteria</p> Signup and view all the answers

    Where are a significant portion of β-lactam antibiotics metabolized?

    <p>Liver</p> Signup and view all the answers

    What does '1 unit' of penicillin represent?

    <p>Amount of Na penicillin that gave a standard zone of inhibition on a standard culture medium</p> Signup and view all the answers

    When did penicillin come into clinical use?

    <p>1940s</p> Signup and view all the answers

    'Pencillin G' is the drug of choice for the initial treatment of infections in which animals?

    <p>Horses and cattle</p> Signup and view all the answers

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