10 Questions
What is the action of β-lactam antibiotics on bacteria?
They dissolve cell wall structures, leading to rupture and death
Where are β-lactam antibiotics primarily excreted?
In the urine
What is the drug of choice for the initial treatment of infections in horses and cattle?
Penicillin
What does '1 unit' of penicillin represent?
Amount of Na penicillin that gave a standard zone of inhibition on a standard culture medium
Why are some penicillins dosed based on units or IU?
The amount of drug needed to produce the desired effect varies
What is the target of β-lactam antibiotics?
Growing & metabolically active bacteria
Where are a significant portion of β-lactam antibiotics metabolized?
Liver
What does '1 unit' of penicillin represent?
Amount of Na penicillin that gave a standard zone of inhibition on a standard culture medium
When did penicillin come into clinical use?
1940s
'Pencillin G' is the drug of choice for the initial treatment of infections in which animals?
Horses and cattle
Test your knowledge of beta-lactam antibiotics including penicillins, cephalosporins, carbapenems, and monobactams. Explore microbial resistance mechanisms like β-lactamases and their impact on bacterial enzymes. Understand the excretion and modification pathways of these antibiotics.
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