Pharmacology and Hormones Overview
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Pharmacology and Hormones Overview

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Questions and Answers

Match the medication with its primary indication or effect:

Magnesium sulfate = Decreased deep tendon reflexes Bismuth subsalicylate = Eliminates toxins Terbutaline = Preterm labor Sildenafil = Erectile dysfunction

Match the condition to its corresponding treatment:

Constipation = Psyllium mucilloid Duodenal ulcers = H2 receptor antagonists BPH symptoms = Tamsulosin Gastric erosion = Sucralfate

Match the vitamin deficiency with its cause:

Folic acid = Alcohol abuse Vitamin K = Malabsorption disorders Vitamin D = Pregnancy Vitamin C = Poor diet

Match the medication to its notable side effect:

<p>Norethindrone = Photosensitivity Ondansetron = QT interval prolongation Conjugated estrogen = Increased risk of blood clots Medroxyprogesterone = Thromboembolic events</p> Signup and view all the answers

Match the contraceptive with its specific guidance:

<p>Oral contraceptives = Effectiveness reduced by certain medications Testosterone patches = Rotate site every 7 days Emergency contraceptive = Choice based on time since intercourse TPN = Given deep IM, change tubing every 24 hours</p> Signup and view all the answers

Match the medication with its characteristics:

<p>PPI's = Inhibits gastric acid secretion Misoprostol = Prevention of peptic ulcers Stool softener = Increases water absorption in stool Antacids = Neutralize acids in the stomach</p> Signup and view all the answers

Match the following medications with their warnings or contraindications:

<p>Selective estrogen receptor modulators = Contraindicated in venous thromboembolism Terbutaline = Black box warning in pregnancy Sildenafil = Contraindicated with nitrates Hormone replacement therapy = Increased risk for MI</p> Signup and view all the answers

Match the therapeutic effects with the medications:

<p>Fluids = Required with psyllium mucilloid use Antibiotics = Reduce the effectiveness of oral contraceptives St. John Wart = Increases risk of breakthrough bleeding Zofran = Used prior to triggers for nausea</p> Signup and view all the answers

Match the medication with its route or method of administration:

<p>TPN = Central line with refrigeration Deep IM medication = Given every 3 months Ondansetron = Administered before triggers H2 receptor antagonists = For duodenal ulcer treatment</p> Signup and view all the answers

Match the medication with its primary use:

<p>Oxytocin = Causes uterine contractions during delivery Finasteride = Treats benign prostatic hyperplasia (BPH) Sulfasalazine = Used for ulcerative colitis Orlistat = Used to treat obesity</p> Signup and view all the answers

Match the medication with its associated side effect:

<p>Finasteride = Sexual dysfunction and impaired fertility Sulfasalazine = Hepatotoxicity Methylnaltrexone = Constipation relief in opioid users Alendronate = Esophageal ulceration and dysphagia</p> Signup and view all the answers

Match the use or characteristics of the medication:

<p>Emergency contraception = Based on time since intercourse Antacid = Neutralizes stomach acid for heartburn relief DMARDS = Slows disease progression and may cause infections 5 Alpha reductase inhibitors = Prevent conversion of testosterone</p> Signup and view all the answers

Match the drug with its special instructions or components:

<p>Alendronate = Must be taken with full glass of water and remain upright Oxytocin = Given during delivery to help regulate contractions Vitamin A = Safe in pregnancy but can cause malformation in excess Methylnaltrexone = Used for chronic constipation in advanced cancer</p> Signup and view all the answers

Match the description with the respective drug:

<p>Oxytocin = Prevents post-delivery hemorrhaging Orlistat = Inhibits fat absorption to aid weight loss Sulfasalazine = Cautious use in severe hepatic or renal impairment Finasteride = Decreases nocturia symptoms</p> Signup and view all the answers

Match the condition with its appropriate treatment:

<p>Chronic constipation = Methylnaltrexone Obesity = Orlistat Uterine contractions = Oxytocin Ulcerative colitis = Sulfasalazine</p> Signup and view all the answers

Match the drug with the outcome related to its use:

<p>DMARDS = Maintain joint function and pain relief Emergency contraception = Prevent unintended pregnancy Antacid = Temporary relief of heartburn symptoms Alendronate = Increase in bone density</p> Signup and view all the answers

Match the medication to its potential risks or considerations:

<p>Vitamin A = Fetal malformation if overdosed Finasteride = Possible sexual side effects Sulfasalazine = Risk of liver damage Methylnaltrexone = Avoids constipation from opioids</p> Signup and view all the answers

Match the drug with its pharmacological category or function:

<p>Oxytocin = Hormonal agent for labor 5 Alpha reductase inhibitors = Prostate treatment Alendronate = Bisphosphonate for osteoporosis DMARDS = Immunosuppressive therapy</p> Signup and view all the answers

Match the drug to its primary action:

<p>Oxytocin = Stimulates uterine contraction Orlistat = Inhibits fat digestion Sulfasalazine = Reduces gut inflammation Finasteride = Lowers prostate size</p> Signup and view all the answers

Match the medication with its primary use or side effect:

<p>Zofran = QT interval dysrhythmias PPI = Inhibits gastric acid production Isotonic fluids = Fluid replacement for GI loss Medroxyprogesterone = Increased thrombolytic risk with smoking</p> Signup and view all the answers

Match the condition with its related treatment or medication:

<p>Peptic Ulcer Disease = Misoprostol Chronic Constipation = Methylnaltrexone Benign Prostatic Hyperplasia = Finasteride Hyperkalemia = Dialysis</p> Signup and view all the answers

Match the medication with its administration-related instruction:

<p>TPN = Move from refrigerator before administration Magnesium Sulfate = Watch for skin flushing and confusion Crystalloids = Fluid replacement containing electrolytes Sodium bicarbonate = Monitor for metabolic alkalosis</p> Signup and view all the answers

Match the medication with its contraindication or warning:

<p>Conjugated estrogen = Uncontrolled uterine bleeding Norethindrone = Photosensitivity risk Sulfasalazine = Caution in severe renal impairment Terbutaline = Limit use to 48-72 hours</p> Signup and view all the answers

Match the medication with its side effect:

<p>Bismuth = Absorbs toxins for diarrhea Potassium = Monitor IV site for irritation Oxytocin = Causes rapid painful contractions Vitamin A = Night blindness risk</p> Signup and view all the answers

Match the medication with the therapeutic area:

<p>5-alpha reductase inhibitors = BPH treatment Oxytocin = Labor induction Colloids = Fluid retention in vessels Estradiol = Oral contraceptive</p> Signup and view all the answers

Match the fluid type with its characteristic:

<p>Hypertonic = Shifts fluid into vascular space Isotonic = No fluid shift Crystalloids = Contain electrolytes for replacement Colloids = Maintain fluid within vessels</p> Signup and view all the answers

Match the condition with its treatment approach:

<p>Active IBD = Reduce symptoms Severe acidosis = Use sodium bicarbonate Preterm labor = Administer terbutaline Hyperkalemia = Use calcium gluconate</p> Signup and view all the answers

Match the condition with the corresponding risk factor:

<p>Conjugated estrogen = Risk of thrombophlebitis over age 35 PPI long-term use = Increased fracture risk Smoking = Increased risk with medroxyprogesterone Nifedipine = Calcium channel blocker</p> Signup and view all the answers

Match the drug with its primary side effect:

<p>Magnesium Sulfate = Muscle weakness in overdose Finasteride = Sexual dysfunction Norethindrone = Decreased skin tolerance to sunlight Zofran = QT interval prolongation</p> Signup and view all the answers

Study Notes

Hormones and Reproductive Health

  • Oxytocin, produced by the pituitary gland, causes uterine contractions and is used during delivery and post-delivery to prevent hemorrhaging, commonly resulting in painful contractions.
  • Testosterone can be used in palliative care for breast cancer to reduce tumor size; patch applications require site rotation every 7 days.
  • Conjugated estrogen treats menopausal symptoms but increases risks of DVT, MI, and dementia; contraindicated in abnormal uterine bleeding.
  • Norethindrone is taken daily to maintain efficacy but may cause photosensitivity and increased risk of breakthrough bleeding with St. John’s Wort.

Treatments and Side Effects

  • Finasteride treats benign prostatic hyperplasia (BPH) and alleviates symptoms like nocturia but may cause sexual dysfunction and impaired fertility.
  • Sulfasalazine treats ulcerative colitis, with a risk of hepatotoxicity; caution advised for severe liver or renal impairment.
  • Methylnaltrexone helps with chronic constipation in cancer patients using opioids.
  • Medroxyprogesterone is a long-term contraceptive administered every 3 months but may lead to thromboembolic events if combined with St. John’s Wort or smoking.

Gastrointestinal and Metabolic Health

  • Antacids provide temporary relief from heartburn by neutralizing stomach acid; absorption may be affected by other medications.
  • H2 receptor antagonists treat duodenal ulcers and prevent recurrence by blocking stomach acid secretion.
  • Proton pump inhibitors (PPIs) inhibit acid production but can take several days for symptom relief; long-term use increases fracture risk.
  • Sucralfate does not affect acid secretion but coats gastric erosion to promote healing.

Pregnancy and Lactation Considerations

  • Vitamin A is safe in recommended amounts during pregnancy, but excessive intake can cause fetal malformations.
  • Folic acid deficiency due to pregnancy, alcohol abuse, or malabsorption requires supplementation.

Cardiovascular and Renal Health

  • Magnesium sulfate relaxes smooth muscle and may be used to delay preterm labor; overdose symptoms include confusion and decreased reflexes.
  • Terbutaline is effective for preterm labor but has a black box warning against use exceeding 72 hours due to potential harm to the fetus.

Miscellaneous

  • Bismuth subsalicylate binds and eliminates toxins, effective for treating diarrhea.
  • Oral contraceptives may become less effective when using certain antibiotics or anticonvulsants, which increase the risk of thrombolytic events.
  • Hyperkalemia treatment depends on kidney function, utilizing glucose, calcium gluconate, and dialysis as necessary.
  • Crystalloids, like Ringer's solution, are used for fluid replacement in hypovolemic shock, while colloids like dextran maintain vascular fluid.

Safety Guidelines

  • Always monitor for dehydration symptoms in enteral feedings and increase fluid intake when using psyllium mucilloid to treat constipation.
  • Avoid alcohol and certain medications to prevent interactions and side effects, especially in hormone replacement therapy (HRT) or contraceptive use.

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Description

Explore essential hormones and medications in this quiz. Learn about oxytocin's role in childbirth, finasteride for BPH symptoms, and treatments for ulcerative colitis. Test your knowledge on drug usage, side effects, and medical applications.

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