18 Questions
Which enzyme is responsible for catalyzing acetylation reactions?
Acetyl transferase
What is the active form of acetic acid involved in acetylation reactions?
Acetyl-CoA
What is the product of the reaction between sulphanilamide and acetic acid?
N-Acetylsulphanilamide
Which of the following compounds is not conjugated with acetic acid?
Nicotinamide
Where are the enzymes responsible for acetylation reactions mainly located?
Cytosol
What is the purpose of acetylation reactions in the body?
To facilitate the excretion of compounds
What is the primary method of detoxification of foreign substances in the human body?
Oxidation
What is the result of the oxidation of methanol?
Formaldehyde and then formic acid
Which of the following is NOT an example of oxidation?
Aspirin to acetic acid and salicylic acid
What is the result of the reduction of picric acid?
Picramic acid
What type of bond is hydrolyzed in the metabolism of aspirin?
Ester bond
Which of the following is an example of a psychoactive drug that undergoes hydrolysis?
Atropine
What is the primary function of Phase II biotransformation reactions?
To convert lipophilic compounds into water-soluble compounds
Which of the following types of Phase II reactions involves the transfer of a glucuronyl group from UDP-glucuronic acid?
Glucuronidation
What is the role of glucuronyl transferase in glucuronidation?
It acts as a catalyst for the reaction
Which of the following compounds is NOT conjugated with glucuronic acid?
Procaine
What is the purpose of conjugation reactions in Phase II biotransformation?
To convert lipophilic compounds into hydrophilic compounds
How many types of Phase II reactions are mentioned in the text?
6
Test your knowledge of pharmacology and biochemistry with this quiz on conjugation reactions, including sulfation and acetylation processes, and the compounds involved in these reactions. Learn about the enzymes and molecules that play a crucial role in these processes. Evaluate your understanding of pharmacological and biochemical concepts.
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