Pathway of Phospholipase A2 and Arachidonic Acid Metabolism Quiz
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Questions and Answers

What is the role of prostaglandins in the body?

  • Induce platelet aggregation and vasoconstriction
  • Contribute to allergic and inflammatory responses
  • Increase release of calcium from the endoplasmic reticulum
  • Promote airway constriction and inflammation (correct)

    • Which enzyme is involved in the conversion of arachidonic acid to leukotrienes?

  • Phospholipase A2
  • Cyclooxygenase
  • Epoxygenase
  • 5-lipoxygenase (correct)

    • What substances are generated by the pathway initiated by epoxygenase?

  • Leukotrienes
  • Arachidonic acid
  • Hydroxyeicosatetraenoic acid (HETE) and cis-epoxyeicosatrienoic acid (EET) (correct)
  • Prostaglandins and thromboxanes

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