Pathophysiology Exam 3 Review

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Questions and Answers

What is the primary process the body uses to restore tissues after injury?

  • Metaplasia
  • Apoptosis
  • Dysplasia
  • Inflammation (correct)

Which of the following best describes how cells respond to stress?

  • They stop producing proteins.
  • They become more susceptible to infections.
  • They undergo necrosis immediately.
  • They adapt to the stress and maintain function. (correct)

The immune response primarily protects the body against what?

  • Infection (correct)
  • Repair failure
  • Cellular hypertrophy
  • Inflammation

Which factor is NOT typically involved in the process of inflammation?

<p>Cellular apoptosis (B)</p> Signup and view all the answers

What is a common outcome when the immune system is unable to respond effectively to an infection?

<p>Chronic inflammation (D)</p> Signup and view all the answers

Which term describes the alteration of normal tissue structure due to prolonged stress or injury?

<p>Metaplasia (C)</p> Signup and view all the answers

In which scenario would you expect increased apoptosis to occur?

<p>In response to viral infections (C)</p> Signup and view all the answers

What is the primary purpose of tissue repair mechanisms?

<p>To restore tissue structure and function (B)</p> Signup and view all the answers

When discussing pathophysiology, what is a critical element that must be understood?

<p>Normal biological processes (C)</p> Signup and view all the answers

Chronic inflammation may lead to which of the following conditions?

<p>Fibrosis or scarring (A)</p> Signup and view all the answers

How do alterations in bowel motility primarily affect stool elimination?

<p>They can cause constipation or diarrhea. (C)</p> Signup and view all the answers

What is a key distinguishing feature between Type 1 and Type 2 diabetes?

<p>Type 1 diabetes requires insulin from diagnosis. (B)</p> Signup and view all the answers

Which complication of diabetes results from excessively high blood sugar levels over time?

<p>Macrovascular disease (C)</p> Signup and view all the answers

Which of the following symptoms is typically associated with diabetic ketoacidosis (DKA)?

<p>Severe dehydration and confusion (A), High levels of ketones in the urine (B)</p> Signup and view all the answers

What is a common non-pharmacological approach to managing Type 2 diabetes?

<p>Regular physical activity (A)</p> Signup and view all the answers

Which statement accurately describes Gestational diabetes?

<p>It typically resolves after childbirth. (D)</p> Signup and view all the answers

What is the primary reason why hypoglycemia can be dangerous?

<p>It can impair brain function. (C)</p> Signup and view all the answers

What physiological changes occur when the serum pH level becomes too acidic or too alkaline?

<p>Cellular functions may be impaired and can lead to organ failure. (A)</p> Signup and view all the answers

Which of the following best indicates the need for diagnosis of diabetes?

<p>Increased thirst and frequent urination (B)</p> Signup and view all the answers

Which buffer system primarily works in the blood to regulate pH levels?

<p>Bicarbonate buffer system (D)</p> Signup and view all the answers

What is a common physiological change seen in patients with diabetes regarding glucose processing?

<p>Inadequate insulin secretion (C)</p> Signup and view all the answers

The Somogyi effect is best described as:

<p>A response to low blood sugar levels during the night. (D)</p> Signup and view all the answers

What is the primary distinction between benign and malignant tumors?

<p>Malignant tumors invade surrounding tissues and can spread. (A)</p> Signup and view all the answers

Which of the following is not a characteristic of neoplastic cells?

<p>Increased cell cohesion (C)</p> Signup and view all the answers

What common age-related change is distinguished from pathological changes?

<p>Decrease in skin elasticity (C)</p> Signup and view all the answers

During the urine production process, what is the principal function of the glomerulus?

<p>Filtration of blood to form urine (D)</p> Signup and view all the answers

Which condition involves the inability to maintain normal urinary motility?

<p>Urinary incontinence (C)</p> Signup and view all the answers

What is the main role of the nephron in the kidneys?

<p>To filter blood and produce urine (A)</p> Signup and view all the answers

Which statement best describes carcinogens?

<p>Substances that promote cancer development through various mechanisms. (D)</p> Signup and view all the answers

Which of the following best illustrates the process of carcinogenesis?

<p>It is the combination of genetic predisposition and environmental influences. (C)</p> Signup and view all the answers

Flashcards

Physiologic pH

A range of pH values that maintain normal cellular function, from slightly acidic to slightly alkaline.

Proliferation

The process of cells dividing and increasing in number.

Differentiation

The process of cells becoming specialized and taking on specific functions.

Neoplasm

An abnormal mass of cells that grows uncontrollably and lacks a normal function.

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Carcinogenesis

The process by which normal cells transform into cancerous cells.

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Genetic Mutations

Changes in DNA sequence that can lead to cancer, caused by environmental factors or errors in DNA replication.

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Carcinogens

Factors that increase the risk of developing cancer, such as smoking, radiation, and certain chemicals.

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Cancer

A group of disorders characterized by uncontrolled growth and spread of abnormal cells.

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Nephron

The functional unit of the kidney, responsible for filtering blood and producing urine.

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Elimination

The process of the body eliminating waste products, primarily through urine and feces.

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Cell Stress Response

The way a cell responds to a harmful or stressful environment.

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Inflammation

A protective response by the body to injury or infection, involving redness, swelling, heat, and pain. It helps to remove the cause of injury and initiate healing.

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Tissue Repair

The process by which damaged or dead tissue is replaced with new tissue.

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Immune Response

The body's defense against infection and disease, involving specialized cells and molecules that identify and destroy harmful invaders.

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Infection

The process by which pathogens enter the body and cause infection.

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Body's Response to Infection

The body's reaction to infection, involving a range of symptoms like fever, pain, fatigue, and inflammation.

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Pathophysiology

The study of how disease processes affect the normal functioning of the body.

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Signs and Symptoms

The outward signs and symptoms of a disease that a doctor can observe or measure.

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Tests

Medical tests used to diagnose and monitor a disease. They can include blood tests, imaging scans, and biopsies.

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Treatment

Treatments aimed at managing or curing a disease. It can include medications, surgery, therapy, and lifestyle changes.

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Diabetes Mellitus

A condition where the body's blood sugar levels are consistently higher than normal. It can cause a wide range of complications.

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Type 1 Diabetes

Type 1 diabetes is an autoimmune disease where the body attacks and destroys the insulin-producing cells in the pancreas. This leads to an inability to produce insulin, and therefore, the body can't regulate blood sugar.

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Type 2 Diabetes

The pancreas can't produce enough insulin, or the body can't use insulin properly, leading to high blood sugar. It's often linked to lifestyle factors like obesity and lack of physical activity.

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Gestational Diabetes

Gestational diabetes develops during pregnancy. This is because hormones during pregnancy can make the body less sensitive to insulin.

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Hyperglycemia

Hyperglycemia is the medical term for high blood sugar. It can occur in people with diabetes or other conditions that affect glucose regulation.

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Hypoglycemia

Hypoglycemia refers to low blood sugar. It can be a serious condition, especially for people with diabetes.

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Diabetic Ketoacidosis (DKA)

Diabetic ketoacidosis (DKA) is a serious complication of diabetes. It occurs when the body produces excess ketones (acids) because it can't use sugar for fuel. DKA is a medical emergency.

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Hyperglycemic Hyperosmolar Nonketotic Syndrome (HHNK)

A serious diabetes complication that causes high blood sugar and dehydration. The body is unable to use glucose for fuel, leading to a build-up of sugar in the blood.

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Glucose Metabolism

A process by which the body converts glucose from food into energy.

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Insulin

A hormone produced by the pancreas that helps regulate blood sugar.

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Study Notes

Exam 3 Review Topics

  • Pathophysiology Exam 3: Covers chapters 9, 19, 7, 18, and 20 of the Applied Pathophysiology textbook.

Chapter 9: Altered Acid-Base Balance

  • Physiological pH: Understanding acidosis and alkalosis through serum (blood) pH levels.
  • Importance of pH: Maintaining physiologic pH is crucial for cell and tissue function.
  • Buffer Systems: The body uses three buffer systems to regulate pH. Details on how they work are needed.
  • Acidosis and Alkalosis: Identify the implications of deviations from the normal pH range on cells and tissues.

Chapter 19: Degenerative Changes in Aging

  • Aging vs. Pathophysiology: Differentiate between expected changes in aging and pathological changes.
  • Manifestations of Aging: Understand the various categories of aging manifestations, using figure 19.2 in the textbook as a guide.
  • Specific Models: Models of osteoporosis and Alzheimer's disease.

Chapter 7: Altered Cellular Proliferation and Differentiation

  • Proliferation vs. Differentiation: Key differences between these two processes (refer to chapter 2 for review).
  • Cancer Definition: Defining cancer and neoplastic cells; describing characteristics of cancer cells.
  • Carcinogenesis: Understand how cancer develops (include genetic mutations and how the body tries to fix them).
  • Cancerogenic Environments: Factors that contribute to the development of cancer (e.g., polymorphisms, epigenetic changes).
  • Cancer Formation and Carcinogens: Learn about carcinogens, how they work, and why they contribute to cancer development.

Chapter 18: Altered Elimination

  • Urine Production and Removal: Explain the function of the nephron and glomerulus, how the kidneys reabsorb and excrete substances.
  • Urine pathway: Describe the journey of urine from the kidneys to outside of the body

Chapter 20: Integrated Pathophysiologic Concepts (Glucose Regulation and Diabetes)

  • Glucose Regulation: Details of how glucose is processed in the body, including the role of insulin and the pancreas.

  • Understanding Diabetes: Understand type 1, type 2, and gestational diabetes, including causes, symptoms, diagnoses, and treatments for each.

  • Specific Complication of Diabetes: Understand complications like microvascular and macrovascular problems, hypoglycemia- issues surrounding DKA and HHNK, Somogyi effects, and dawn phenomenon.

General Studying Advice

  • Studying Techniques: Emphasize diverse study methods combining textbooks, notes, lecture videos, and concept maps.
  • Key Concepts: Learn fundamental concepts about cellular responses, inflammation, tissue repair, and immune system responses.
  • Focus on Core Concepts: Don't get bogged down in details, rather focus on understanding core principles of each disease process and how body functions when stressed.
  • Use real-world examples: Using real-world diagnoses and their breakdown into pathophysiology, clinical signs and symptoms, diagnostic tests, and treatment options to aid in understanding.

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