Podcast
Questions and Answers
What are the three classes of carcinogenic agents?
What are the three classes of carcinogenic agents?
Chemicals, radiant energy, microbial agents
What are the two stages of chemical carcinogenesis?
What are the two stages of chemical carcinogenesis?
Initiation and Promotion
What is the difference between direct-acting and indirect-acting agents?
What is the difference between direct-acting and indirect-acting agents?
Direct-acting agents require no metabolic conversion to become carcinogenic, while indirect-acting agents require metabolic conversion to an ultimate carcinogen before becoming active.
What are examples of indirect-acting agents?
What are examples of indirect-acting agents?
What is the main cause of carcinogenesis according to the text?
What is the main cause of carcinogenesis according to the text?
What is the multistep nature of carcinogenesis attributed to?
What is the multistep nature of carcinogenesis attributed to?
What is the primary target for chemical carcinogens?
What is the primary target for chemical carcinogens?
What type of radiation is derived from sunlight and has the ability to damage DNA by forming pyrimidine dimers?
What type of radiation is derived from sunlight and has the ability to damage DNA by forming pyrimidine dimers?
What is the essential first step in the process of initiation in carcinogenesis?
What is the essential first step in the process of initiation in carcinogenesis?
What type of UV is carcinogenic?
What type of UV is carcinogenic?
What is the mechanism by which UV rays damage DNA?
What is the mechanism by which UV rays damage DNA?
What provides the best evidence for the increased risk of skin cancer in sun-exposed parts of the body?
What provides the best evidence for the increased risk of skin cancer in sun-exposed parts of the body?
What is the role of initiators in the process of carcinogenesis?
What is the role of initiators in the process of carcinogenesis?
What is the effect of exposure to promoters on initiated cells?
What is the effect of exposure to promoters on initiated cells?
What is the primary effect of most chemical carcinogens?
What is the primary effect of most chemical carcinogens?
What is the mechanism by which ionizing radiation can lead to carcinogenesis?
What is the mechanism by which ionizing radiation can lead to carcinogenesis?
