Pathology Lecture 2: Inflammation
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Questions and Answers

What is the result of dilatation of lymphatics in inflammation?

  • No change in lymph flow
  • Lymph flow stops
  • Decreased lymph flow
  • Increased lymph flow (correct)

    • What are the two processes of cellular responses in acute inflammation?

  • Inflammation and repair
  • Exudation of platelets and erythrocytes
  • Exudation of leucocytes and phagocytosis (correct)
  • Lymphatic and blood flow regulation

    • What is the first step of leukocytic exudation?

  • Rolling
  • Emigration
  • Adhesion
  • Margination or pavementation (correct)

    • What type of molecules mediates the rolling of leukocytes?

    <p>Selectin</p> Signup and view all the answers

    What is the function of integrins in leukocytic exudation?

    <p>Firmly sticks leukocytes to endothelial cells</p> Signup and view all the answers

    What is the term for the passive passage of RBCs to the area of inflammation?

    <p>Diapedesis</p> Signup and view all the answers

    What is the term for the movement of motile white cells from the blood vessels to the perivascular tissue?

    <p>Emigration</p> Signup and view all the answers

    What is the term for the attraction of leucocytes towards the site of injury?

    <p>Chemotaxis</p> Signup and view all the answers

    What is the main purpose of delivering leukocytes and mediators to the site of injury?

    <p>To deliver leukocytes and mediators to the site of injury by the blood stream</p> Signup and view all the answers

    What is the result of the local vascular reaction in acute inflammation?

    <p>Transient vasoconstriction followed by vasodilatation</p> Signup and view all the answers

    What is the main cause of slowing of blood stream in acute inflammation?

    <p>All of the above</p> Signup and view all the answers

    What is the primary mechanism of formation of fluid exudate in acute inflammation?

    <p>All of the above</p> Signup and view all the answers

    What is the characteristic of the fluid inflammatory exudate in terms of protein content?

    <p>High protein content (4-8 gm%)</p> Signup and view all the answers

    What is the function of the fibrin network in the inflammatory response?

    <p>All of the above</p> Signup and view all the answers

    What is the result of contraction of endothelial cells in acute inflammation?

    <p>Increased vascular permeability</p> Signup and view all the answers

    What is the role of high fibrinogen in the inflammatory response?

    <p>To form a network that helps movement of acute inflammatory cells</p> Signup and view all the answers

    What is the primary goal of inflammation in response to an injury?

    <p>To eliminate or limit the spread of the injurious agent</p> Signup and view all the answers

    What is the main difference between acute and chronic inflammation?

    <p>Acute inflammation has a short duration, while chronic inflammation has a long duration</p> Signup and view all the answers

    Which of the following is an example of a physical agent that can cause inflammation?

    <p>Excessive heat</p> Signup and view all the answers

    What is the suffix used to denote inflammation in medical terminology?

    <p>itis</p> Signup and view all the answers

    What is the term for the immediate response of living tissue to an injury?

    <p>Acute inflammation</p> Signup and view all the answers

    What is the primary function of opsonins in phagocytosis?

    <p>Facilitation of attachment</p> Signup and view all the answers

    Which of the following is a characteristic of chronic inflammation?

    <p>Gradual onset</p> Signup and view all the answers

    What is the process of engulfment in phagocytosis characterized by?

    <p>Formation of pseudopods around the injurious agent</p> Signup and view all the answers

    What is the role of inflammation in achieving healing and repair?

    <p>It prepares the affected tissue for repair</p> Signup and view all the answers

    Which of the following is NOT a mechanism involved in killing and degradation of microorganisms in phagocytosis?

    <p>Chemotaxis</p> Signup and view all the answers

    What is the term for the fluid that accumulates at the site of inflammation as a result of increased permeability of blood vessels?

    <p>Exudate</p> Signup and view all the answers

    What is the term for the process of cell movement in response to chemical stimuli?

    <p>Chemotaxis</p> Signup and view all the answers

    What is the resulting structure formed after the fusion of a phagocytic vacuole with lysosomal granules?

    <p>Phagolysozome</p> Signup and view all the answers

    What is the role of C5a in leukocytic exudation?

    <p>Chemotactic factor</p> Signup and view all the answers

    What is the primary cause of redness in acute inflammation?

    <p>Vascular dilatation</p> Signup and view all the answers

    Which of the following is a result of leukocytosis?

    <p>Increased number of leukocytes</p> Signup and view all the answers

    What is the primary cause of pain in acute inflammation?

    <p>Direct action of chemical mediators on sensory nerve endings</p> Signup and view all the answers

    Which of the following is a characteristic of chronic infections?

    <p>Lymphocytosis</p> Signup and view all the answers

    What is the primary cause of fever in acute inflammation?

    <p>Action of cytokines on the thermoregulatory centre of the hypothalamus</p> Signup and view all the answers

    What is the result of resolution in acute inflammation?

    <p>Complete restoration of the inflamed area to the normal state</p> Signup and view all the answers

    What is the primary cause of anemia in acute inflammation?

    <p>Toxic depression of the bone marrow</p> Signup and view all the answers

    What is the result of reactive hyperplasia in acute inflammation?

    <p>Reactive hyperplasia of the draining lymph nodes</p> Signup and view all the answers

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