Pathology Cellular Degeneration and Necrosis

What is a characteristic microscopically observed in cellular swelling?

Which of the following necrosis types appears dry and crumbly?

What causes coagulation necrosis?

Which of the following is a description of the appearance of fat necrosis?

What microscopic feature indicates fatty change in cells?

Which necrosis type is typically associated with dying neutrophils?

What gross description fits coagulation necrosis?

What is NOT a cause of fat necrosis?

Cellular Degeneration

Cellular Swelling (Hydropic Degeneration):
- Macroscopically: No visible change, tissue bulges on sectioning
- Microscopically: Individual cells swollen, pale cytoplasm or small clear vacuoles, hydronic or vacuolar degeneration
Fatty Change:
- Macroscopically: Variable sized vacuoles from fat accumulation, cells pale, nuclei pushed to edge of cell, friable, greasy

Types of Necrosis

Coagulation Necrosis:
- Gross description: Firmer, drier on cut surface, resembling adjacent tissue outline, cells larger, outline lost, cytoplasm structure homogenous, nucleus lost, abscesses
- Cause/Examples: Bacterial toxins, infarction, viral replication
Liquefactive Necrosis:
- Gross description: Pus- usually has a capsule
- Cause/Examples: Progenic organisms, bacteria, dying neutrophils
Caseous Necrosis:
- Gross description: White to grey to yellow colour, dry and crumbly, mixture of coagulative and liquefactive areas, focal opacity, hard consistency
- Cause/Examples: Mycobacterium tuberculosis, fungi
Fat Necrosis:
- Gross description: Not detailed in this context.
- Cause/Examples: Pancreatitis, traumatic necrosis, diet related (deficient in antioxidants)

Explore the mechanisms and types of cellular degeneration and necrosis in this quiz. From hydropic degeneration to various forms of necrosis, test your knowledge on the distinctions and characteristics of these pathological processes. Ideal for students studying pathology or related fields.