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Questions and Answers
What is necrosis characterized by?
What is necrosis characterized by?
- Rapid repair of a tissue area
- Inflammatory response without tissue death
- Gradual decline in cellular function
- Rapid death of a limited area (correct)
Which term describes the entire process of cell degeneration and death?
Which term describes the entire process of cell degeneration and death?
- Pyknosis
- Karyolysis
- Necrosis
- Necrobiosis (correct)
Which characteristic is used to differentiate necrotic tissue from autolysis?
Which characteristic is used to differentiate necrotic tissue from autolysis?
- Increased vascularization
- Color variation within tissue
- Presence of a zone of inflammation (correct)
- Presence of ghost nuclei
What does pyknosis refer to in cellular characteristics of necrosis?
What does pyknosis refer to in cellular characteristics of necrosis?
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Which process implies sudden death of the nucleus?
Which process implies sudden death of the nucleus?
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What does karyolysis result in?
What does karyolysis result in?
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Study Notes
Necrosis Overview
- Necrosis involves rapid death of cells within a localized area, marking the final stage of irreversible degeneration.
- Necrobiosis refers to the complete process of cellular degeneration and ultimate death.
Gross Characteristics
- Affected tissue appears pale, soft, and friable, distinctly separated from viable tissue.
- Clear delineation exists between necrotic and healthy tissue, characterized by a zone of inflammation.
- The separation must be sharp, differentiating necrosis from autolysis.
Cellular Features of Necrosis
- Pyknosis: Occurs with nuclear chromatin condensing into a dark, round, homogeneous mass that is smaller than the original nucleus.
- Karyorrhexis: The nucleus splits into numerous smaller fragments, indicating a sudden, severe cellular death.
- Karyolysis: Involves the dissolution of nuclear chromatin, resulting in a large, hollow, ghost-like nucleus.
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