Parkinson's Disease: Symptoms, Epidemiology, and Prognosis

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Cell death in the substantia Nigra, leading to dopamine depletion

<p>Dopamine is the main driver of motor cortex activation</p> Signup and view all the answers

<p>It indicates that cell death has progressed beyond a critical point</p> Signup and view all the answers

<p>The typical age range for the onset of Parkinson's disease is over 60 years old, and the term for the condition if it occurs prior to the age of 50 is young onset-PD.</p> Signup and view all the answers

<p>The most common presenting symptom of Parkinson's disease is tremor, and about 30% of patients do not show tremor.</p> Signup and view all the answers

<p>The term for the slowed movement and loss of spontaneous movement characteristic of Parkinson's disease is akinesia (also known as bradykinesia), and it affects the ability to perform activities of daily living, leading to a loss of independence and quality of life.</p> Signup and view all the answers

<p>The brain region affected in Parkinson's disease is the basal ganglia, and its main components include the dorsal striatum, globus pallidus, substantia nigra, and subthalamic nucleus.</p> Signup and view all the answers

<p>Some of the non-motor symptoms of Parkinson's disease include psychiatric disturbances, autonomic disturbances, cognitive impairment, sleep disturbances, and cholinergic disturbances, and these symptoms can significantly impact quality of life, leading to decreased independence, mood changes, and cognitive decline.</p> Signup and view all the answers